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Autor:
Reza Norouzirad, Asghar Ghasemi, Hamideh Afzali, Mohammad Khaksari, Khosrow Kashfi, Sajad Jeddi
Publikováno v:
Nitric Oxide. 103:20-28
Decreased nitric oxide bioavailability in skin contributes to impaired wound healing in type 2 diabetes (T2D). This study aims at determining effects of acidified nitrite on wound closure as well as inflammatory and antioxidants markers in wound tiss
Publikováno v:
Nitric Oxide
Activation of renin-angiotensin- system, nitric oxide (NO•) bioavailability and subsequent sympathoexcitation plays a pivotal role in the pathogenesis of many cardiovascular diseases, including hypertension. Previously we have shown increased prote
Autor:
Denisa Rusu, Silvanna Verlezza, Hong Long, Claire-Dominique Walker, Barbara Woodside, Emily A. Opala
Publikováno v:
Neuroscience. 417:95-106
Reproductive experience is associated with morphological and functional plasticity in brain areas important for cognitive and emotional responses, including the infralimbic (IL) medial prefrontal cortex (mPFC). Here we examined whether suboptimal con
Publikováno v:
Bone
There is currently an unmet clinical need for improved treatments for skeletal diseases such as osteoporosis and cancer-induced bone disease. This is due in part to a paucity of novel targets and an incomplete understanding of the mechanisms of actio
Autor:
Iulia Glovaci, C. Andrew Chapman
Publikováno v:
Cell Calcium. 80:103-111
The entorhinal cortex plays an important role in temporal lobe processes including learning and memory, object recognition, and contextual information processing. The alteration of the strength of synaptic inputs to the lateral entorhinal cortex may
Publikováno v:
Physiol Behav
Objective This report reflects a meta-analysis that systematically reviewed the literature on intravenous self-administration (IVSA) of nicotine in female and male rats. The goal was to determine if sex differences in nicotine IVSA exist, estimate th
Publikováno v:
Peptides. 115:1-7
26RFa is an endogenous ligand for the QRFP receptor. We previously found that intracerebroventricular injection of 26RFa produces an analgesic effect in a rat formalin test. In the present study, we directly tested the hypothesis that the analgesic e
Autor:
Lindsey Boman, Maxine De Butte
Publikováno v:
Behavioural Brain Research. 363:155-160
Despite substantial increases in the use of antipsychotics to treat various psychiatric conditions in children, there is a lack of literature regarding long-term effects of early treatment. Some studies have indicated that early administration result
Publikováno v:
Pharmacology Biochemistry and Behavior. 179:89-97
The Gateway Hypothesis is based on epidemiological data and states there is a progression of drug use from use of a softer drug (e.g., nicotine) to use of a harder drug (e.g., morphine). It has been suggested that this sequence is causal and is relev
Publikováno v:
Prostaglandins & Other Lipid Mediators. 141:1-10
We recently reported that celecoxib, a selective cyclooxygenase-2 (COX2) inhibitor, counteracts the adverse circulatory and renal actions of cyclosporine (CSA). Despite the seemingly advantageous nature of this interaction particularly in clinical se