Zobrazeno 81 - 90
of 1 280
pro vyhledávání: '"35"'
Publikováno v:
Laboratory Investigation. 102:691-701
Gliomas are the most common primary intracranial tumor, accounting for more than 70% of brain malignancies. Studies indicate that highly upregulated in liver cancer (HULC), a long noncoding RNA (lncRNA), functions as an oncogene in gliomas. However,
Publikováno v:
Biochemical and Biophysical Research Communications. 427:606-610
Endothelin Converting Enzyme-1 (ECE-1) is essential for the production of the potent vasoconstrictor Endothelin-1 (ET-1). The activation of Protein Kinase C (PKC) by phorbol 12-myristate 13-acetate (PMA) can increase ECE-1 phosphorylation, which in t
Autor:
Lisa G. Shaffer, Lynda J. Campbell, Theresa C. Brown, Marilyn L. Slovak, Aubry Furrow, Jin Yeong Han, Roger A. Schultz, Meaghan Wall, Blake C. Ballif, Kathryn A. Kolquist
Publikováno v:
Cancer Genetics. 204:603-628
The myelodysplastic syndromes (MDS) are a heterogeneous group of clonal disorders characterized by ineffective hematopoiesis, cytopenias, and a risk of transformation to acute myeloid leukemia (AML). However, only approximately 50% of primary MDS pat
Publikováno v:
Journal of Biological Chemistry. 286:32002-32010
The physiological roles of taurine, a product of cysteine degradation and one of the most abundant amino acids in the body, remain elusive. Taurine deficiency leads to heart dysfunction, brain development abnormalities, retinal degradation, and other
Autor:
P.Y. Loung, C.W. Cheng, W.Y. Tse, L.M. Wong, Y.Y. Lam, S.C. Tiu, Angel O.K. Chan, K.L. Ng, C.Y. Lee, W.M. But, Ruth Charlton, K.F. Lee, Ian R. Berry, C.C. Shek, Rebecca Brown, Y.C. Ho
Publikováno v:
Steroids. 76:1057-1062
Background Congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency (21OHD) is an autosomal recessive disorder due to mutation in the CYP21A2 gene. Objective To elucidate the genetic basis of 21-hydroxylase-deficient CAH in Hong Kong
Autor:
Arash Grakoui, Marlène Dreux, Nishi R. Sharma, Gregory B. Melikyan, Guaniri Mateu, François-Loïc Cosset
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (35), pp.30361-30376. ⟨10.1074/jbc.M111.263350⟩
Journal of Biological Chemistry, 2011, 286 (35), pp.30361-30376. ⟨10.1074/jbc.M111.263350⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (35), pp.30361-30376. ⟨10.1074/jbc.M111.263350⟩
Journal of Biological Chemistry, 2011, 286 (35), pp.30361-30376. ⟨10.1074/jbc.M111.263350⟩
International audience; Hepatitis C virus (HCV) entry into permissive cells is a complex process that involves interactions with at least four co-factors followed by endocytosis and low pH-dependent fusion with endosomes. The precise sequence of rece
Publikováno v:
Toxicology in Vitro. 25:545-554
The PR CALUX® cell line is a stably transfected human U2-OS cell line expressing the human PR and a luciferase reporter construct containing three progesterone-responsive elements coupled to a minimal promoter. The validity of this assay has been st
Publikováno v:
Blood Cells, Molecules, and Diseases. 45:313-316
The aim of this study was to investigate whether a single nucleotide polymorphism (SNP) +874T/A of interferon-gamma (IFN-γ) correlates with response to immunosuppressive therapy. Amplification refractory mutation system-polymerase chain reaction was
Autor:
Changgong Wu, Andrew M. Parrott, Mohit Jain, Tong Liu, Cexiong Fu, Hong Li, Wei Chen, Shinichi Oka, Junichi Sadoshima, Ahmet Tarik Baykal
Publikováno v:
Molecular & Cellular Proteomics : MCP
Transnitrosylation and denitrosylation are emerging as key post-translational modification events in regulating both normal physiology and a wide spectrum of human diseases. Thioredoxin 1 (Trx1) is a conserved antioxidant that functions as a classic
Publikováno v:
Journal of Biological Chemistry. 285:19854-19864
Metabolic labeling with [(35)S]cysteine was used to characterize early events in CaSR biosynthesis. [(35)S]CaSR is relatively stable (half-life approximately 8 h), but maturation to the final glycosylated form is slow and incomplete. Incorporation of