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Autor:
Jiarui Wang, Xianqin Zhang, Tingting Zou, Dazhi Zhang, Wenqiang Liu, Zhenxing Liu, Xuejie Peng, Zhengyi Ni, Yang Tan, Meiqi Hou, Mi Zhou, Chao Yuan, Xiaopei Zhou
Publikováno v:
Biochemical and Biophysical Research Communications. 591:124-129
Mendelian susceptibility to mycobacterial disease (MSMD) is a rare monogenetic disease, which is characterized by susceptibility to some weakly virulent mycobacteria. Here, we explored the pathogenic genes and molecular mechanisms of MSMD patients. W
Autor:
Muhammad Nadeem, Syed Sarim Imam, May Bin-Jumah, Imran Kazmi, Sadaf Jamal Gilani, Sultan Alshehri
Publikováno v:
International Journal of Biological Macromolecules. 194:338-346
Presented research aimed to develop a spray drying process without the use of organic solvents for the preparation of novel Karaya gum polymer microparticles (MPs) of Ganoderma lucidum polysaccharide (GLP). The prepared microparticles were characteri
Autor:
Rafael C. Dutra, Jaíne Ferrareis Menegasso, Tatiana Pineda Vásquez, Nayara Alves Celinca Moraes, Regina Vasconcellos Antônio, Francielly Andressa Felipetti
Publikováno v:
International Journal of Biological Macromolecules. 194:402-411
The main objective of this study was to investigate the effects of bacterial cellulose hydrogel (BCH) incorporated into montmorillonite (MMT) and its underlying mechanisms of action on a skin wound healing mouse model following pressure injury model.
Autor:
Ruyi Xue, Shengxian Li, Ji-Cheng Li, Lai-Xi Wang, W.W. Zhang, Youping Li, T.Y. Mi, X.L. Yin, Yueming Zhang, Hai-Tao Wang, Xu Shen, Yan Zhang
Publikováno v:
Biochemical and Biophysical Research Communications. 586:121-128
Postoperative fatigue (POF) is the most common and long-lasting complication after surgery, which brings heavy burden to individuals and society. Recently, hastening postoperative recovery receives increasing attention, but unfortunately, the mechani
Autor:
Li Li, Glenda C. Gobe, David A. Vesey, Christudas Morais, Rajagopalan Prasanna, Evan P. Owens, Hossam Kamli
Publikováno v:
Biochemical and Biophysical Research Communications. 586:42-48
Sunitinib is one of the first-line multi-tyrosine kinase inhibitors for metastatic renal cell carcinoma, and resistance to sunitinib continues to be a limiting factor for the successful treatment. As interleukin-6 (IL-6) is overexpressed in sunitinib
Autor:
Xue Liu, Qian Xu, Qiuhua Wu, Yang Wu, Cheng Jiamin, Yulin Liu, Bhavesh D. Kevadiya, Manling Chen, Yang Li, Guolin Zhang, Avnesh S. Thakor
Publikováno v:
Acta Biomaterialia. 136:485-494
Carbon nanodots based on L-arginine (L-Arg) were developed for enhanced nitric oxide (NO) gas therapy for cancer. The L-Arg-based carbon nanodots (Arg-dots) produced high levels of NO in the tumor environment rich in endogenous H2O2. In vitro cell ex
Autor:
Vikas Rana, Radhika Sharma
Publikováno v:
International Journal of Biological Macromolecules. 193:1301-1312
In present work, a film forming gel (FFG) was developed through ingenious amalgamation of polymers: Pullulan, Terminalia catappa and Carbopol®971P ® for cutaneous delivery of clotrimazole (CTZ) employing D-optimal mixture design. The developed FFG
Autor:
Hossein Ghafouri, Samad Muhammadnejad, H. Delavari, Nastaran Moradi, Mohammad Ali Oghabian, Negin Pournoori
Publikováno v:
International Journal of Biological Macromolecules. 192:72-81
The conjugation of monoclonal antibodies with superparamagnetic iron oxide nanoparticles (SPIONs) has appeared as a potential multifunctional clinical tool, which can effectively diagnose cancers and monitor their treatment, specifically. Despite the
Publikováno v:
International Journal of Biological Macromolecules. 192:241-249
Intestinal epithelial cells (IECs) offer a primary physical barrier against commensal and pathogenic microorganisms in the gastrointestine. However, the influence of IECs on the development and regulation of mucosal immunity to infection is unknown.
Autor:
Sommaya M. Sharaf, Ibrahim M. El-Sherbiny, El-Sayed M. El-Sayed, Saif El-Din Al-Mofty, Ahmed S. Abo Dena, Amina Omar
Publikováno v:
International Journal of Biological Macromolecules. 193:2029-2037
Every year, about 1 out of 9 get burnt in Egypt, with a mortality rate of 37%, and they suffer from physical disfigurement and trauma. For the treatment of second-degree burns, we aim at making a smart bandage provided with control of drug release (u