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Autor:
Naim Alkhouri, Stephen A. Harrison, Rohit Loomba, Jerry R. Colca, Bo Hyun Lee, Kenneth Cusi, Orville G. Kolterman, Christopher L. Edwards, Gad Cotter, Arun J. Sanyal, Beth A. Davison, Howard C. Dittrich
Publikováno v:
Journal of Hepatology. 72:613-626
Background & Aims MSDC-0602K is a novel insulin sensitizer designed to preferentially target the mitochondrial pyruvate carrier while minimizing direct binding to the transcriptional factor PPARγ. Herein, we aimed to assess the efficacy and safety o
Autor:
Radwan Massoud, Rihab Nasr, Rami Mahfouz, Raafat Alameddine, Jean El Cheikh, Nathalie K. Zgheib, Ammar Zahreddine, Ali Bazarbachi
Publikováno v:
Current Research in Translational Medicine. 68:51-58
To evaluate polymorphisms in genes of drug metabolizing enzymes and transporters involved in cyclosporine and/or voriconazole disposition among patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT).DNA from forty patients was g
Publikováno v:
Revista Internacional de Andrología. 18:55-62
Introduction and objectives Testicular ischemia/reperfusion (I/R) injury develops after torsion and following detorsion of the testis. Reactive oxygen species were produced and oxidative damage begins to occur due to I/R process. Nimesulide, which is
Autor:
Edith Carton, Yohann Loriot, Grégoire Marret, Karim Fizazi, Pernelle Lavaud, Giulia Baciarello, Stéphane Culine, Emeline Colomba, Christophe Massard, Olivier Huillard, Laurence Albiges, Jérôme Alexandre
Publikováno v:
European Journal of Cancer. 129:117-122
Background Abiraterone acetate (abiraterone) combined with prednisone is a standard of care in metastatic castration-resistant prostate cancer. Recently, benefit in overall survival was reported in metastatic castration-sensitive prostate cancer also
Publikováno v:
Journal of Surgical Research. 247:1-7
Background Reactive oxygen species–induced cell injury has been considered to be one of the main etiologic factors in ischemia-reperfusion injury (IRI). As a potential antioxidant agent, epigallocatechin gallate (EGCG) was examined in skeletal musc
Publikováno v:
The Journal of Nutrition
Background 25-Hydroxycholecalciferol [25(OH)D] is the predominant circulating metabolite of vitamin D and serves as the precursor for 1α,25-dihydroxycholecalciferol [1,25(OH)2D], the hormonally active form. The presence of 1α-hydroxylase (1α-OHase
Publikováno v:
Toxicology Letters. 320:9-18
Pranoprofen (PPF) is a wildly used anti-inflammatory ophthalmic drug. It was reported that PPF could decrease early epithelialization of scrape wounds in rabbit cornea and could reduce cell activities of cultured human corneal endothelial cells. Howe
Autor:
Hiroshi Nakagawa, Masahiro Ohishi, Kensyo Matsuda, Hideaki Katsuyama, Kazuhiko Nishimura, Arisa Hirabayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 523:54-59
Promotion of erythropoietin (EPO) production is important for erythropoiesis as well as cell viability. The most effective inducing factor for EPO production is hypoxia. Hypoxia inducible factor (HIF), a regulator of EPO production, is increased unde
Publikováno v:
European Neuropsychopharmacology. 31:131-144
Amitriptyline is prescribed for treating the symptoms of neuroinflammatory disorders including neuropathic pain and fibromyalgia. As amitriptyline has evidence of modulating the neuroimmune interface; the effects of amitriptyline treatment on T-cell
Publikováno v:
Poultry Science
Poultry Science, Vol 99, Iss 1, Pp 95-100 (2020)
Poultry Science, Vol 99, Iss 1, Pp 95-100 (2020)
This present experiment was performed to investigate the effects of dietary supplementation of chitosan (CS) on immune function in growing Huoyan geese. A total of 320 28-day-old healthy growing Huoyan geese (sex balance) with similar body weight wer