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Publikováno v:
Brain Research Bulletin. 172:120-128
A modulatory role has been reported for the isoflavone, genistein, on voltage-gated Na+ channels in the trigeminal ganglion in vitro. However, the acute effects of genistein in vivo, particularly on nociceptive transmission in the trigeminal system,
Publikováno v:
NeuroToxicology. 84:208-217
Methamphetamine is used extensively around the world as a psychostimulant. The complications related to methamphetamine include methamphetamine-induced neurotoxicity, mainly involving intraneuronal processes, such as oxidative stress and excitotoxici
Autor:
Angelika Langsch, Rainer Otter, Christine Palermo, Sander van den Driesche, Serena Shoker, Fiona Inglis
Publikováno v:
van den Driesche, S, Shoker, S, Inglis, F, Palermo, C, Langsch, A & Otter, R 2020, ' Systematic Comparison of the Male Reproductive Tract in Fetal and Adult Wistar Rats exposed to DBP and DINP in utero during the Masculinisation Programming Window ', Toxicology Letters . https://doi.org/10.1016/j.toxlet.2020.10.006
This study investigates possible effects of in utero exposure of rats to a low dose (125 mg/kg bw/day) and a high dose (750 mg/kg bw/day) of Diisononyl phthalate (DINP) during the masculinisation programming window (MPW) which is embryonic days 15.5-
Publikováno v:
Reproductive Toxicology. 98:92-98
The synthetic food preservative sodium benzoate (SB) is widely used in both food and pharmaceutical industries. A growing body of evidence highlights the adverse effects of SB on human health; however, effect of the prolonged intake of SB on the repr
Publikováno v:
Toxicology Letters. 333:97-104
Proton pump inhibitors (PPIs) have wide pleiotropic action in addition to their therapeutic potential in gastroesophageal reflux diseases. Conversely, recent reports revealed a significant incidence of toxic events of PPIs including nephritis, osteop
Autor:
Nikolaos Mpalantes, Despoina Papageorgouli, Nikolaos Pitsikas, Panagiota Fallon, Alkiviadis Papageorgoulis
Publikováno v:
Nitric Oxide. 99:1-6
Sodium nitroprusside (SNP) is a nitric oxide (NO) donor which actually is under assessment as a potential candidate for the treatment of schizophrenia. It is well documented that anxiety symptoms are a prominent future in various psychiatric diseases
Publikováno v:
Revista Internacional de Andrología. 18:55-62
Introduction and objectives Testicular ischemia/reperfusion (I/R) injury develops after torsion and following detorsion of the testis. Reactive oxygen species were produced and oxidative damage begins to occur due to I/R process. Nimesulide, which is
Autor:
Hiroshi Nakagawa, Masahiro Ohishi, Kensyo Matsuda, Hideaki Katsuyama, Kazuhiko Nishimura, Arisa Hirabayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 523:54-59
Promotion of erythropoietin (EPO) production is important for erythropoiesis as well as cell viability. The most effective inducing factor for EPO production is hypoxia. Hypoxia inducible factor (HIF), a regulator of EPO production, is increased unde
Autor:
Juergen Pauluhn
Publikováno v:
Toxicology Letters. 316:94-108
The toxic effects resulting from inhalation exposure depend on both the concentration (C) of the inhaled substance and the exposure duration (t), including the assumptions that the exposure-limiting toxic effect is linearly linked with the accumulate
Autor:
Joseph Ngakou Mukam, Idrice Kamtchouing, Paul Aimé Noubissi, René Kamgang, Michel Archange Fokam Tagne, Angèle Foyet Fondjo, Adela Ngwewondo, Henri Wambe, Gaëtan Olivier Fankem
Publikováno v:
Journal of Integrative Medicine. 17:438-445
Infectious diseases such as typhoid fever lead to the formation of free radicals which can damage the body. Many medicinal plants have antioxidant molecules that neutralize free radicals. The present work evaluated the antioxidant activity and histop