Zobrazeno 241 - 250
of 7 780
pro vyhledávání: ''
Autor:
Qiang Gao, Yu Wu, Dawei Wang, Hao Zhong, Qiu-Li Wu, Cong Xing, Guangzhi Ning, Shiqing Feng, Bo Li, Haodong Qu, Shibo Zhu, Ru‐Sen Zhu
Publikováno v:
Biochemical and Biophysical Research Communications. 526:793-798
Low-intensity pulsed ultrasound (LIPUS) is widely used to regulate stem cell proliferation and differentiation. However, the effect of LIPUS stimulation on neural stem cells (NSCs) is not well documented. In this study, we have identified the optimal
Publikováno v:
Magnetic Resonance Imaging. 68:75-82
Background and purpose We develop a method of imaging exosomes in vivo according to the vital role of exosomes in intercellular communication. This study aims to design a new label method that allows the visualization of labeled exosomes with magneti
Autor:
Jonathan Malola, Huan-Tian Zhang, Jie Yang, Xiao-Zhen Zhan, Jogendra Singh Pawar, Zhengang Zha, Zhen-Yan Li
Publikováno v:
Differentiation. 113:38-48
Thy-1 is a 25–37 kDa glycophosphatidylinositol (GPI)-anchored cell surface protein that was discovered more than 50 years ago. Recent findings have suggested that Thy-1 is expressed on thymocytes, mesenchymal stem cells (MSCs), cancer stem cells, h
Publikováno v:
Journal of Bioscience and Bioengineering. 129:632-637
Transplantation of stem cell-derived myoblasts is a promising approach for the treatment of skeletal muscle function loss. Myoblasts directly converted from somatic cells that bypass any stem cell intermediary stages can avoid the problem of tumor fo
Autor:
Natalie Weber, Kathrin Kowalski, Tim Holler, Ante Radocaj, Martin Fischer, Stefan Thiemann, Jeanne de la Roche, Kristin Schwanke, Birgit Piep, Neele Peschel, Uwe Krumm, Alexander Lingk, Meike Wendland, Stephan Greten, Jan Dieter Schmitto, Issam Ismail, Gregor Warnecke, Urs Zywietz, Boris Chichkov, Joachim Meißner, Axel Haverich, Ulrich Martin, Bernhard Brenner, Robert Zweigerdt, Theresia Kraft
Publikováno v:
Stem Cell Reports
Summary Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) represent an attractive model to investigate CM function and disease mechanisms. One characteristic marker of ventricular specificity of human CMs is expression of the ventricular,
Autor:
Phillippa J. Carling, William James, Rowan Flynn, Walther Haenseler, Monika Stegmann, Jane Vowles, Heyne Lee, Sally A. Cowley, Francesca J. Nicholls, Ishta Sharma, Emma R. Haberman, Richard Wade-Martins
Publikováno v:
Stem Cell Reports
Summary The Parkinson's disease-associated gene, LRRK2, is also associated with immune disorders and infectious disease and is expressed in immune subsets. Here, we characterize a platform for interrogating the expression and function of endogenous L
Publikováno v:
Stem Cell Reports
Summary Engineered CRISPR/Cas9-based transcriptional activators can potently and specifically activate endogenous fate-determining genes to direct differentiation of pluripotent stem cells. Here, we demonstrate that endogenous activation of the PAX7
Autor:
Kyle S. Coots, Kevin T. Nella, Christian B. Roque, Hsiang-Tsun Chang, Akihiro J. Matsuoka, Rachel A. Heuer, Tammy L. McGuire, Andrew M. Oleksijew
Publikováno v:
Acta Biomater
Although the application of human embryonic stem cells (hESCs) in stem cell-replacement therapy remains promising, its potential is hindered by a low cell survival rate in post-transplantation within the inner ear. Here, we aim to enhance the in vitr
Publikováno v:
Biochemical and Biophysical Research Communications. 525:563-569
Supercentenarians (≥110-year-old, SC) are a uniquely informative population not only because they surpass centenarians in age, but because they appear to age more slowly with fewer incidences of chronic age-related disease than centenarians. We rep
Publikováno v:
Biochemical and Biophysical Research Communications. 525:1038-1045
Human trophoblast stem cells (TSCs) play a key role in the placenta. These cells are proliferative, undifferentiated, and can differentiate into mature trophoblast cell types. However, primary human TSCs are difficult to obtain. In our previous study