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Publikováno v:
Biochemical and Biophysical Research Communications. 577:6-11
Premature ovarian failure (POF) is defined by amenorrhea, hypoestrogenism, elevated gonadotropin levels, and infertility. Chemotherapeutic agents are the most gonadotoxic agents that lead to POF. Although some previous studies have presented that mes
Autor:
Bo Zhu, Shengkun Wang, Sijia Lu, Shaoning Yu, Huayan Yang, Junbiao Chang, Shouning Yang, Lihong Liu
Publikováno v:
International Journal of Biological Macromolecules. 191:192-200
When nanoparticles (NPs) come into contact with bioenvironments, a protein corona forms on the NP surface. Previous reports showed that the constituents of the corona change with time. However, how different protein corona compositions influence cell
Autor:
Jinqi Wang, Haozhen Lv, Xuanhao Zeng, Yating Liu, Qi Zhang, Jinhua Xu, Weiling Lian, Kelu Wei
Publikováno v:
Biochemical and Biophysical Research Communications. 573:151-157
Although surgical interventions have become optional for refractory vitiligo, grafting related injuries is inevitable. Embryonic stem cell (ESC) derivatives can be used in transplantation to address this issue, but the immune rejection due to allogen
Autor:
Karen E. Brown, Amanda G. Fisher
Publikováno v:
Current Opinion in Genetics & Development. 70:15-23
The conversion of differentiated cells to a pluripotent state through somatic cell nuclear transfer provided the first unequivocal evidence that differentiation was reversible. In more recent times, introducing a combination of key transcription fact
Publikováno v:
Semin Cell Dev Biol
Congenital Heart Disease (CHD), malformations of the heart present at birth, is the most common class of life-threatening birth defect (Hoffman (1995) [1] , Gelb (2004) [2] , Gelb (2014) [3] ). A major research challenge is to elucidate the genetic d
Publikováno v:
Journal of Bioscience and Bioengineering. 132:390-398
The dynamic migratory behavior of human mesenchymal stem cells (hMSCs) has a significant impact on the epigenetic profiles that determine fate choice and lineage commitment during differentiation. Here we report a novel approach to enhance repeated m
Autor:
Atsushi Tsuchida, Hirai Kakuro, Sayaka Sekiya, Kenji Yoshida, Akiyoshi Kishino, Saito Hikaru, Atsushi Nakane, Masaharu Kiyama, Jun Takahashi, Shizu Takeda, Kunio Ohyama, Toru Kimura, Hiroko Hanzawa, Midori Kato
Publikováno v:
Journal of Bioscience and Bioengineering. 132:381-389
To improve cell production efficacy, it is important to evaluate cell conditions during culture. Extracellular vesicles (EVs) secreted from various cells are involved in stem cell differentiation. As EVs carry information about their source cells, we
Publikováno v:
Dev Biol
Human organoids stand at the forefront of basic and translational research, providing experimentally tractable systems to study human development and disease. These stem cell-derived, in vitro cultures can generate a multitude of tissue and organ typ
Autor:
Andrew J. Lund, Istvan Mody, John Huang, Inma Cobos, William E. Lowry, Marcos Otero-Garcia, Justin Langerman, Ranmal A. Samarasinghe, Kathrin Plath, Damon Polioudakis, Shan Sabri, Xiaofei Wei, Bennett G. Novitch, Daniel H. Geschwind, Thomas F. Allison
Publikováno v:
Stem cell reports, vol 16, iss 10
Stem Cell Reports
Stem Cell Reports
Summary The specification of inhibitory neurons has been described for the mouse and human brain, and many studies have shown that pluripotent stem cells (PSCs) can be used to create interneurons in vitro. It is unclear whether in vitro methods to pr
Autor:
Mikael Wiberg, Paul J. Kingham, Maria Brohlin, Peyman Kelk, Rebecca Wiberg, Anne Therese Lauvrud, Rojda Gümüscü
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 74:2759-2767
Summary Introduction Water jet-assisted liposuction has gained popularity due to favourable fat grafting outcomes. In this study, we compared stem cells obtained from fat isolated with manual or the water jet-assisted procedure. Methods Liposuction o