Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kevin J Harrington"'
Autor:
Fiona Taylor, Manish Monga, Makoto Tahara, Stefan Kasper, Francis P. Worden, Michael DeRosa, Caroline Even, Everett E. Vokes, Lisa Licitra, Robert L. Ferris, Robert I. Haddad, George R. Blumenschein, Kim Cocks, Jérôme Fayette, James W. Shaw, Nabil F. Saba, Naomi Kiyota, Laura Morrissey, Joël Guigay, Maura L. Gillison, Mark Lynch, A. Dimitrios Colevas, Kevin J. Harrington, Viktor Grünwald
Publikováno v:
The Lancet Oncology. 18:1104-1115
Summary Background Patients with platinum-refractory recurrent or metastatic squamous cell carcinoma of the head and neck have few treatment options and poor prognosis. Nivolumab significantly improved survival of this patient population when compare
Autor:
Shreerang Bhide, Aisha Miah, Sarah L. Gulliford, James P Morden, Kevin J. Harrington, Shane Zaidi, Katie L. Newbold, Emma Hall, Christopher M. Nutting
Publikováno v:
Clinical Oncology (Royal College of Radiologists (Great Britain)
Aims To establish whether there is a difference in recovery of salivary function with bilateral superficial lobe parotid-sparing intensity-modulated radiotherapy (BSLPS-IMRT) versus contralateral parotid-sparing IMRT (CLPS-IMRT) in patients with loca
Autor:
Katie L. Newbold, Kevin J. Harrington, Punita Lal, Ulrike Schick, Joanna Lynch, Shreerang Bhide, Christopher M. Nutting
Publikováno v:
Oral Oncology. 50:901-906
Summary Background Ipsilateral radiotherapy is an established technique for treating well-lateralised tonsillar tumours. Concerns exist regarding the risk of contralateral nodal failure, particularly in patients with ipsilateral nodal involvement at
Autor:
Melanie Valenti, Suzanne A. Eccles, Gary Box, Kevin J. Harrington, Alexis De Haven Brandon, Bissan Al-Lazikani, Anna Wilkins, Susanne J. Rogers, Marta Mendiola, Carol Box, Sharon Gowan
Publikováno v:
European Journal of Cancer. 49:2512-2521
Background Acquired resistance to tyrosine kinase inhibitors (TKIs) is becoming a major challenge in the treatment of many cancers. Epidermal growth factor receptor (EGFR) is overexpressed in squamous carcinomas, notably those of the head and neck (H
Autor:
S. Gupta, Katie L. Newbold, Ulrike Schick, Kevin J. Harrington, Anna Wilkins, N. Rosenfelder, Khin Thway, S.A. Bhide, Christopher M. Nutting
Publikováno v:
Oral Oncology. 49:615-619
Background: Carboplatin can be substituted for cisplatin in concomitant chemoradiation (CRT) for locally advanced squamous cell carcinoma of the head and neck (LASCCHN) when the latter is contraindicated. This matched-pair study aimed to compare the
Autor:
Catharine H. Clark, Aisha Miah, A. Margaret Bidmead, Jennifer Hickey, Robyn Nicol, Yolanda Barbachano, M. Teresa Guerrero-Urbano, Suzanne St. Rose, Kevin J. Harrington, Roger A'Hern, Shreerang Bhide, Kate Newbold, Mary Anne Lagmay Tanay, Christopher M. Nutting
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 82:539-547
Purpose To determine the safety and outcomes of induction chemotherapy followed by dose-escalated intensity-modulated radiotherapy (IMRT) with concomitant chemotherapy in locally advanced squamous cell cancer of the larynx and hypopharynx (LA-SCCL/H)
Publikováno v:
European Journal of Cancer. 47:520-529
Vascular endothelial growth factors (VEGF-C and VEGF-A) play important roles in tumour-induced lymphangiogenesis and angiogenesis, respectively, key processes implicated in promoting tumour growth and metastatic spread. Previous work from our laborat
Autor:
Sarah L. Gulliford, Katie L. Newbold, Christopher M. Nutting, Shreerang Bhide, Jack F. Fowler, Kevin J. Harrington, Nicola Rosenfelder
Publikováno v:
Radiotherapy and Oncology. 97:86-91
Purpose: This study describes the acute response of oral and pharyngeal mucosa to chemo-IMRT schedules using different doses per fraction. Materials and methods: Patients, treated in prospective trials of concomitant chemo-IMRT with 2.17 Gy, 2.25 Gy
Autor:
Cheryl Richardson, S. Brennan, Angela Riddell, Merina Ahmed, K. Burke, Mark R. Davies, Christopher M. Nutting, Christine Kong, Kevin J. Harrington, Maria A. Schmidt, Aslam Sohaib, Kate Newbold, Marianne Usher
Publikováno v:
Radiotherapy and Oncology. 94:161-167
Introduction Magnetic resonance imaging (MRI) provides superior diagnostic accuracy over computed tomography (CT) in oropharyngeal tumours. Precise delineation of the gross tumour volume (GTV) is mandatory in radiotherapy planning when a GTV boost is
Autor:
Raghav C. Dwivedi, Christopher M. Nutting, Rehan Kazi, Shailesh Khode, Kapila Manikantan, Rajan Palav, Peter Rhys-Evans, Kevin J. Harrington
Publikováno v:
Cancer Treatment Reviews. 35:744-753
Follow-up in patients treated for head and neck cancer (HNC) is aimed at early detection of recurrence, metastases and second primary tumours. Various modalities for the routine follow-up of patients with HNC have been proposed and studied in the lit