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Publikováno v:
Microvascular Research. 65:56-60
Tumor blood flow (TBF) plays a fundamental role in tumor growth and treatment, and is characterized by spatial and temporal heterogeneities. Here we show that the interstitial fluid pressure (IFP), which is higher in tumoral tissue than in normal tis
Publikováno v:
Microvascular Research. 53:128-141
The growth of tumors and their response to treatment are determined by delivery of diffusible substances to cancer cells and hence by their blood supply. Relative to most normal tissues, tumor blood flow is highly heterogeneous. Several hypotheses ha