Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maria Diaz"'
Autor:
Diana Rommelfanger-Konkol, Peter Selby, Timothy Kottke, Elizabeth Ilett, Kevin J. Harrington, Karishma Rajani, Shane Zaidi, Hardev Pandha, Jose S. Pulido, O Donnelly, Alan Melcher, Richard G. Vile, Rosa Maria Diaz, Vanesa Alonso-Camino, Jill Thompson
Publikováno v:
Molecular Therapy. 22(11):1936-1948
Previously, we showed that vesicular stomatitis virus (VSV) engineered to express a cDNA library from human melanoma cells (ASMEL, Altered Self Melanoma Epitope Library) was an effective systemic therapy to treat subcutaneous (s.c.) murine B16 melano
Autor:
Alan Melcher, Feorillo Galivo, Jill Thompson, Kevin J. Harrington, Steven M. Albelda, Rosa Maria Diaz, Timothy Kottke, Phonphimon Wongthida, Candice Willmon, Richard G. Vile
Publikováno v:
Molecular Therapy. 19(1):140-149
Despite having potent oncolytic activity, in vitro, direct intratumoral injection of oncolytic vesicular stomatitis virus (VSV) into established AE17ova mesothelioma tumors in C57Bl/6 mice had no therapeutic effect. During studies to combine systemic
Autor:
Jill Thompson, Rosa Maria Diaz, Phonphimon Wongthida, Timothy Kottke, Alan Melcher, Feorillo Galivo, Richard G. Vile
Publikováno v:
Molecular Therapy. 19:150-158
We show here, for the first time to our knowledge, that the antitumor therapy of oncolytic vesicular stomatitis virus (VSV) in the B16ova model depends upon signaling through myeloid differentiation primary response gene 88 (MyD88) in host cells. VSV
Autor:
Scott E. Strome, Timothy Kottke, Phonphimon Wongthida, Candice Willmon, Feorillo Galivo, Richard G. Vile, Jose S. Pulido, John D. Chester, Alan Melcher, Kevin J. Harrington, Rosa Maria Diaz, Peter Selby, Karen M. Kaluza, Glen N. Barber, Jill Thompson
Publikováno v:
Molecular Therapy. 16(12):1910-1918
To protect viral particles from neutralization, sequestration, nonspecific adhesion, and mislocalization following systemic delivery, we have previously exploited the natural tumor-homing properties of antigen-specific CD8+ T cells. Thus, OT-I T cell
Autor:
Ahmad Al-Sabbagh, Celia Aparecida Almeida Chaves Garcia, Cristiane Zaccarias, Blanca Maria Diaz-Bardales, Leonilda M.B. Santos, J. K. Sakurada
Publikováno v:
Experimental Parasitology. 89:304-311
Some autoimmune diseases are thought to arise after an infection. Infectious agents can initiate a chronic inflammatory response associated with autoimmune reactions. Chagas disease, caused by the intracellular parasite Trypanosoma cruzi, is an excel
Autor:
Kevin G. Shim, Vanesa Alonso-Camino, Jill Thompson, Laura Evgin, Elizabeth Ilett, Richard G. Vile, Karishma Rajani, Amanda L. Huff, Jose S. Pulido, Rosa Maria Diaz, Alan Melcher, Tim Kottke, Kevin J. Harrington, Shane Zaidi, Peter Selby, Hardev Pandha
Publikováno v:
Molecular Therapy. 24:S28
We showed previously that expressing tumor-associated antigens (TAA) from Vesicular Stomatitis Virus (VSV) eradicates established tumors. We show here that truncation of TAA expressed from VSV can occur to preserve the ability of the virus to replica
Publikováno v:
Molecular Therapy. 11:S280-S281
Low levels of gene delivery in vivo using non-replicating retroviral vectors has severely limited their application for clinical protocols. Therefore, we have investigated the potential of replication-competent retroviruses for cancer gene therapy. T