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Publikováno v:
Genes & Diseases. 10:542-553
Periodontitis is an oral chronic inflammatory disease. Inhibiting tissue destruction and promoting tissue regeneration are important means for the treatment of periodontitis. Metformin not only has hypoglycemic effect but also has anti-inflammatory e
Autor:
Ramachandregowda Sowbhagya, Sindhaghatta Kariyappa Anupama, Muthu Thiruvengadam, Abdulelah Aljuaid, Sumreen Sultana, Mazen Almehmadi, Tekupalli Ravikiran, Ahmed H. Qasem, Mohammad N. Alomary, Saad Alghamdi, Shital Manohar Punekar, Thimmappa R. Lakshmeesha, Santosh Anand, Mohammad Azam Ansari
Publikováno v:
South African Journal of Botany. 151:25-33
Aging is associated with functional decline and structural deteriorations of the myocardium and plays a crucial role in cardiovascular ailments. Decalepis hamiltonii (Dh) is well known medicinal plant used in traditional medicine and exhibits potent
Publikováno v:
Journal of Controlled Release. 349:634-648
Tau-specific immunotherapy is an attractive therapeutic strategy for the treatment of Alzheimer’s disease and other tauopathies. However, targeting tau effectively remains a considerable challenge due to the restrictive nature of the blood-brain ba
Autor:
Hong-Hao Zhou, Song-Xia Zhang, Zhi-Rong Tan, Li-jie Chen, Wei Zhang, Yao Chen, Yu-ligh Liou, Ying Xu, Jing Guo, Xiao-ping Chen
Publikováno v:
Journal of Advanced Research. 39:319-332
Pharmacokinetic variability in disease state is common in clinical practice, but its underlying mechanism remains unclear. Recently, gut microbiota has been considered to be pharmacokinetically equivalent to the host liver. Although some studies have
Publikováno v:
Genes & Diseases. 9:959-972
Recently, cardiovascular diseases (CVDs) were identified as the leading cause of mortality, imposing a heavy burden on health care systems and the social economy. Nicotinamide adenine dinucleotide (NAD+), as a pivotal co-substrate for a range of diff
Autor:
Minxia Huang, Wang Biye, Jun Liu, Jin Jiahua, Yuanyuan Xuan, Liqin Ding, Shengwen Li, Tian Lan, Guizhi Yang
Publikováno v:
Liver Research. 6:93-102
Background and aim Liver fibrosis resulting from persistent liver injury represents a major healthcare problem globally. Traditional Chinese medicine has played an essential role in the treatment of liver fibrosis in recent years. Thus, this study ai
Autor:
Hilmy Ramadhan Wicaksono, Thessy Dewi Anisari, Didit Erwin Saputra, Dimas Adhi Pradana, Asih Triastuti, Namira Lianika, Sitarina Widyarini
Publikováno v:
Journal of Traditional and Complementary Medicine. 12:219-224
Background and aim Plantago major has long been used for medical purposes in Indonesia. However, reports on the anti-arthritic activities of P. major are limited. Experimental procedure The anti-arthritic properties of an n-hexane-insoluble fraction
Autor:
Mariana Elizabeth Troncoso, María F. García Bustos, María José Germanó, Carlos Gamarra Luques, Esteban Sebastián Lozano, Diego Esteban Cargnelutti
Publikováno v:
Journal of Traditional and Complementary Medicine. 12:281-286
Background and aim Prosopis strombulifera (Lam.) Benth is a rhizomatous shrub native from different zones of Argentine Republic. P. strombulifera aqueous extract (PsAE) has different effects and several biological activities have been reported. The g
Autor:
Mathieu J.F. Crupi, Douglas J. Mahoney, Rebecca C. Auer, Sarah Tucker, Adrian Pelin, D. William Cameron, Taylor R Jamieson, Ricardo Marius, John C. Bell, Réjean Lapointe, Kyle Potts, Nikolas T. Martin, Zaid Taha, Ragunath Singaravelu, Taha Azad, Jean-François Cailhier, Joanna Poutou, Bradley Austin, Jean-Simon Diallo, Emily E.F. Brown, Jack Whelan, Christiano Tanese de Souza, Sarwat T. Khan, Reza Rezaei, Julia Petryk, Carolina S. Ilkow, Stephen Boulton, Jonathan B. Angel, Jaahnavi Dave, Xiaohong He, Abera Surendran
Publikováno v:
Molecular Therapy
The coronavirus disease 2019 (COVID-19) pandemic requires the continued development of safe, long-lasting, and efficacious vaccines for preventive responses to major outbreaks around the world, and especially in isolated and developing countries. To
Publikováno v:
Journal of Ginseng Research. 46:435-443
Background Post-traumatic stress disorder (PTSD) is a psychiatric disease that develops following exposure to a traumatic event and is a stress-associated mental disorder characterized by an imbalance of neuroinflammation. Korean red ginseng (KRG) is