Zobrazeno 1 - 10
of 85
pro vyhledávání: '"35"'
Autor:
Fang Wang, Xi Chen, Haiting Mao, Shengnan Hao, Ying He, Wenjuan Gao, Zhonghua Zhao, Jia Liu, Qianqian Shao, Dong Sun
Publikováno v:
Cytokine. 108:43-52
IL-35, a novel IL-12 family member, is a potent inhibitory cytokine predominantly produced by regulatory T and B lymphocytes that exerts optimal suppression in immune response. However, it remains unclear whether IL-35 plays an inhibitory role on hum
Publikováno v:
Clinica Chimica Acta. 462:90-95
Early onset sepsis (EOS) remains a major cause of morbidity and mortality in newborns; however, current diagnostic tools are inadequate. We evaluated the accuracy of a novel cytokine, interleukin (IL)-35, for the diagnosis of EOS in comparison with o
Publikováno v:
Cytokine. 75:389-402
The aim of the study was to characterize and to quantify peripheral and tissue. IL-35- and IL-37-producing cells in Inflammatory Bowel Disease (IBD) patients. We studied a total of 38 active UC, 31 inactive UC, 17 active CD, and 13 inactive CD and 50
Autor:
Rui Jia, Haiting Mao, Chuanxin Wang, Shaoshui Chen, Zhonghua Zhao, Mianli Li, Shengnan Hao, Xi Chen, Nana Wang
Publikováno v:
Cytokine. 89:76-81
Interleukin-35 (IL-35) is a recently discovered inhibitory cytokine, which is firstly discovered to be produced by regulatory T cells (Tregs) and proposed as a key effector molecule of Treg function. This study aims to analyze the correlation between
Autor:
Li Wang, Fanpeng Zhao, Ying Zhu, Shi Liu, Linbai Ye, Shengli Zhu, Jian Feng, Tao Han, Gang Xu, Yinglong She
Publikováno v:
Journal of Biological Chemistry
Interleukin-35 (IL-35) is a newly described member of the IL-12 family. It has been reported to inhibit inflammation and autoimmune inflammatory disease and can increase apoptotic sensitivity. Little is known about the role of IL-35 during viral infe
Publikováno v:
Cytokine. 81:23-27
Postinfluenza pneumococcal pneumonia is an important cause of global morbidity and mortality. What causes this increased susceptibility is not well elucidated. IL-35 is a newly described cytokine in infectious tolerance. A murine model was establishe
Autor:
Shu Meng, Xinyuan Li, Xiaojin Sha, Xiaofeng Yang, Hang Xi, Huimin Shan, Hong Wang, Xiaohua Jiang, Massimo Maddaloni, David W. Pascual
Publikováno v:
Journal of Biological Chemistry. 290:19307-19318
Vascular response is an essential pathological mechanism underlying various inflammatory diseases. This study determines whether IL-35, a novel responsive anti-inflammatory cytokine, inhibits vascular response in acute inflammation. Using a mouse mod
Autor:
Klára Prajzlerová, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt, Hana Hulejová, David Veigl, Zdenka Vernerová, Mária Filková
Publikováno v:
Cytokine. 73:36-43
Objective Interleukin-35 (IL-35) is a heterodimeric member of the IL-12 family consisting of p35/IL-12a and EBI3/IL-27b subunits. Expressed in murine Treg cells, IL-35 controls inflammatory diseases in mouse models. However, human IL-35 is expressed
Autor:
Naveen Arora, Vikram K Jain, Shakuntala Lavasa, Bharti Arora, Swati Sharma, Shailendra Nath Gaur
Publikováno v:
Molecular Immunology. 137:84-93
Background Prosopis juliflora is a clinically relevant allergic sensitizer worldwide and shares cross-reactivity with allergens from several tree pollen and food. The present study aims to purify and immunobiochemically characterize a major allergen
Autor:
Dlzar Dlshad, Ghafoor
Publikováno v:
Cytokine. 161:156082
This study aims to estimate the level of malondialdehyde (MDA) as oxidative stress marker and reduced glutathione (GSH) as antioxidant and correlate them to different inflammatory markers as interleukins (IL-6, IL-8, IL-10) and tumor necrosis factor