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pro vyhledávání: ''
Autor:
Peter J. Kneuertz, Morgan Fitzgerald, Desmond M. D’Souza, Mahmoud Abdel-Rasoul, Robert E. Merritt
Publikováno v:
Clinical Lung Cancer. 22:e574-e583
Background Stage I non–small-cell lung cancer (NSCLC) is potentially curable with surgical resection. Significant proportions of patients may still experience recurrence and death despite undergoing curative surgery. This study describes predictive
Autor:
Toshihide Yokoyama, Takashi Yokoi, Satoru Miura, Shunsuke Teraoka, Shuji Murakami, Kazushige Wakuda, Yuko Oya, Motohiro Tamiya, Atsushi Nakamura, Takaaki Tokito, Keisuke Tomii, Kenichi Yoshimura, O. Yamaguchi, Nobuyuki Yamamoto, Satoshi Watanabe, Hiroshige Yoshioka, Tetsuhiko Asao, Shoichi Itoh, D. Fujimoto, Akihiro Tamiya, Hiroshi Yokouchi, Koji Haratani
Publikováno v:
European Journal of Cancer. 150:63-72
Introduction Despite the extensive use of the combination of cytotoxic chemotherapy and programmed cell death protein 1/programmed death-ligand 1 checkpoint inhibitors for cancer treatment, the incidence and characteristics of pneumonitis caused by t
Autor:
Rebecca Fahy, Moritz Kleine, Tim Reese, Bernd Feyerabend, Kim C Wagner, Karl J. Oldhafer, Mareike Ehmke, Mirco Küchler, Richard Drexler
Publikováno v:
Pancreatology. 21:170-179
Background Transcriptional enhanced associated domain (TEAD) transcription factors are nuclear effectors of several oncogenic signalling pathways including Hippo, WNT, TGF-s and EGFR pathways that interact with various cancer genes. The subcellular l
Autor:
Thomas Tsitsias, Tom Routledge, John Pilling, Lukacs Veres, Lawrence Okiror, Juliet King, Karen Harrison-Phipps, Andrea Bille
Publikováno v:
Lung Cancer. 151:84-90
Objective to validate the proposed N descriptor revision on a large cohort of patients and assess the impact of tumour location on the distribution pattern of lymph node metastases for patients with NSCLC. Methods This is a retrospective review of a
Autor:
Norihiro Sato, Keiji Hirata, Toshiyuki Nakayama, Shiro Kohi, Yasuhiro Adachi, Yuzan Kudo, Hirotsugu Noguchi, Atsuhiro Koga, Takao Amaike
Publikováno v:
Pancreatology. 20:1479-1485
Background Abnormal metabolism of hyaluronan (HA), a major component of extracellular matrix, is a hallmark of cancer. Our previous studies have shown the importance of enzymes responsible for HA degradation in the aggressive phenotype of pancreatic
Publikováno v:
Pancreatology. 20:1502-1510
Background Pancreatic cancer remains one of the most lethal cancers. Objective This study aimed to analyze T cell-related biomarkers and their molecular network in pancreatic cancer. Methods RNAseq sequencing data and clinical data of pancreatic canc
Autor:
Sang Hoon Ahn, Beom Kyung Kim, Seung Hoon Beom, Hye Won Lee, Kwang Hyub Han, Do Young Kim, Hwa Kyung Byun, Hye Jin Choi, Jun Yong Park, Seung Up Kim, Jinsil Seong
Publikováno v:
Ann Transl Med
Purpose Although sorafenib as a standard of care for advanced hepatocellular carcinoma (HCC) prolongs overall survival (OS), its efficacy is limited owing to its unsatisfactory objective response and marginal survival benefit. To counter these limita
Autor:
Chisako Ito, Tomonori Nakazato, Masahiro Akimoto, Yuriko Nishiyama-Fujita, Aki Sakurai, Yuki Osada, Shinji Ogura, Yoshinobu Aisa
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 20:122-129
The ABO blood group is reported to be associated with survival for several types of malignancy. We conducted a retrospective study to evaluate the prognostic significance of the ABO blood group in patients with malignant lymphoma.A total of 523 patie
Autor:
Marilyn Heng, Abha Gupta, Peter W. Chung, John H. Healey, Max Vaynrub, Peter S. Rose, Matthew T. Houdek, Patrick P. Lin, Andrew J. Bishop, Francis J. Hornicek, Yen-Lin Chen, Santiago Lozano-Calderon, Ginger E. Holt, Ilkyu Han, David Biau, Xiaohui Niu, Nicholas M. Bernthal, Peter C. Ferguson, Jay S. Wunder, Takafumi Ueda, Shigeki Kakunaga, Akira Kawai, Hideshi Sugiura, Teruki Kidani, Toshiyuki Kunisasa, Toshifumi Ozaki, Keisuke Ae, Akihito Nagano, Takatoshi Ohno, Koji Hiraoka, Norio Yamamoto, Hiroyuki Tsuchiya, Yoshihiro Matsumoto, Takashi Yanagawa, Robart Nakayama, Hideo Morioka, Tadahiko Kubo, Shoji Simose, Yoshiki Yamagami, Tetsuji Yamamoto, Motohiro Kawasaki, Tomoaki Torigoe, Yasuo Yazawa, Toru Akiyama, Tabu Gokita, Jun Manabe, Mitsunori Kaya, Makoto Emori, Tomoki Nakamura, Akihiko Matsumine, Shinsuke Sugihara, Masahiro Yokouchi, Setsuro Komiya, Yoshiyuki Suehara, Tatsuya Takagi, Teruya Kawamoto, Junji Wasa, Tsukasa Yonemoto, Takeshi Ishii, Ichiro Baba, Manabu Hoshi, Kenichiro Hamada, Norifumi Naka, Tsukasa Sotobori, Nobuhito Araki, Tomotake Okuma, Takahiro Goto, Hiroshi Kobayashi, Hirotaka Kawano, Masami Hosaka, Hiroyuki Futani, Hiroaski Hiraga, Yoshihiro Nishida, Anthony Griffin, Albiruni R.Abdul Razak, David Benjamin Shultz, Charles Catton, Steven Robinson, Shreyaskumar R. Patel, Valerae O. Lewis, B. Ashleigh Guadagnolo, Thomas DeLaney, Haotong Wang, Kevin Raskin, Alexandra K. Callan, Robert Henshaw, Marc Isler, Sophie Mottard, Wei-Ming Chen, Frank Traub, Tom Wei-Wu Chen, Robert E. Turcotte, Darin Davidson, Per-Ulf Tunn, Herbert Loong, Michelle Ghert, Joel Werier, Paul Clarkson, John A. Abraham
Publikováno v:
Eur J Cancer
Purpose The role of chemotherapy (CT) and radiotherapy (RT) for management of extraskeletal osteosarcoma (ESOS) remains controversial. We examined disease outcomes for ESOS patients and investigated the association between CT/RT with recurrence and s
Publikováno v:
Clin Lymphoma Myeloma Leuk
Background Myelofibrosis (MF), a rare disorder characterized by bone marrow fibrosis, has been implicated as a cause of pulmonary hypertension (PH). To date, studies examining this association have not looked at the impact of PH on survival in MF. We