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Autor:
Gulce Naz Yazici, Halis Suleyman, Ercument Keskin, Mehmet Gül, Abdullah Erdogan, Mukadder Sunar
Publikováno v:
Revista Internacional de Andrología. 20:S17-S23
This study aimed to biochemically and histopathologically investigate the effect of sunitinib on oxidative testicular damage induced by ischemia/reperfusion in rats.Experimental animals were divided into three groups of six rats each: testicular tors
Autor:
Charles D. Varnell, Veronica Taylor, Meredith Harris, Bin Zhang, Elif Erkan, Susan Tulley Nehus
Publikováno v:
J Ren Nutr
Objective Hypervitaminosis A is well-described but overlooked in chronic kidney disease (CKD) and has been associated with hypercalcemia, contributing to mineral bone disease. Our objective is to assess prevalence of hypervitaminosis A and its associ
Autor:
Daniel M. Berney, Jonathan Shamash, T. Oliver, Anju Sahdev, S. J. Harland, Andrew Gogbashian, Constantine Alifrangis, Gordon J. S. Rustin, Samita Agarwal, Marina Milic, Sarah Duncan, Sara Stoneham, Shafi Chowdhury, Anand Sharma, Michelle Lockley, Peter Wilson
Publikováno v:
European Journal of Cancer. 164:105-113
Background Radiotherapy and cisplatin-based combination chemotherapy are accepted standard-of-care treatments for metastatic seminoma with excellent survival outcomes but with established short- and long-term morbidity. Carboplatin monotherapy may be
Autor:
Liming Liang, Prescott G. Woodruff, Michimasa Fujiogi, Zhaozhong Zhu, Eugene P. Rhee, Kohei Hasegawa, Yoshihiko Raita, Carlos A. Camargo
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Infants with bronchiolitis are at increased risk for developing asthma. Growing evidence suggests bronchiolitis is a heterogeneous condition. OBJECTIVE: To identify biologically-distinct subgroups based on the metabolome signatures (metab
Autor:
Armen N. Akopian, Paulino Barragán-Iglesias, Andi Wangzhou, Galo L. Mejia, Stephanie Shiers, Diana Tavares-Ferreira, Salim Megat, Ishwarya Sankaranarayanan, Gregory Dussor, Ruta Uttarkar, Pradipta R. Ray, Theodore J. Price
Publikováno v:
Biol Psychiatry
BackgroundThere are clinically relevant sex differences in acute and chronic pain mechanisms, but we are only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed sex differe
Autor:
Xin Zhou, Jiaxian Chen, Wen Hu, Jin Tian, Lulu He, Tingting Feng, Baoju Wang, Keke Ren, Yingyan Lu, Lingling Yang, Shaoli You, Zhanglu An, Bing Zhu, Jun Li, Jing Jiang, Xingping Zhou, Beibei Guo, Peng Li, Tan Li, Li Jiaqi, Jinjin Luo, Shaojie Xin, Dongyan Shi, Hui Yang, Xin Chen, Suwan Sun, Xiaojun Jin, Qun Cai, Xi Liang, Li Jiang, Jiaojiao Xin, Tianzhou Wu
Publikováno v:
Journal of Hepatology. 75:1104-1115
BACKGROUND & AIMS Early determination of the prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is important to guide clinical management and decrease mortality. The aim of this study was to develop a new s
Autor:
Peter J. Sterk, Michel van Weeghel, Tamara Dekker, Abilash Ravi, Annika W.M. Goorsenberg, Jouke T. Annema, Nick H. T. ten Hacken, Frédéric M. Vaz, Annemiek Dijkhuis, Yanaika S. Sabogal Piñeros, Pallav L. Shah, Barbara Dierdorp, René Lutter, Peter I. Bonta
Publikováno v:
Journal of Allergy and Clinical Immunology, 148(5), 1236-1248. MOSBY-ELSEVIER
Background: Asthma is a heterogeneous disease with differences in onset, severity, and inflammation. Bronchial epithelial cells (BECs) contribute to asthma pathophysiology.Objective: We determined whether transcriptomes of BECs reflect heterogeneity
Autor:
Hui Min Leung, Lael M. Yonker, Guillermo J. Tearney, Anika L. Marand, Grace Park, Lauren B. Guthrie, Hanna T. Pinsky, Daniel Irimia, Sinan K. Muldur, Alex Hopke, Bryan P. Hurley, Denis De la Flor
Publikováno v:
J Cyst Fibros
BACKGROUND: Excessive neutrophil inflammation is the hallmark of cystic fibrosis (CF) airway disease. Novel technologies for characterizing neutrophil dysfunction may provide insight into the nature of these abnormalities, revealing a greater mechani
Publikováno v:
Brazilian Journal of Otorhinolaryngology v.87 n.6 2021
Brazilian Journal of Otorhinolaryngology
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
Brazilian Journal of Otorhinolaryngology, Volume: 87, Issue: 6, Pages: 702-710, Published: 06 DEC 2021
Brazilian Journal of Otorhinolaryngology, Vol 87, Iss 6, Pp 702-710 (2021)
Brazilian Journal of Otorhinolaryngology
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
Brazilian Journal of Otorhinolaryngology, Volume: 87, Issue: 6, Pages: 702-710, Published: 06 DEC 2021
Brazilian Journal of Otorhinolaryngology, Vol 87, Iss 6, Pp 702-710 (2021)
Introduction: Functions attributed to androgens have increased, ranging from the role in hypothalamic-pituitary-gonadal axis and reproductive behaviors to modulation of cognition, mood and some other functions. Sex differences and changes in circulat
Publikováno v:
The American Journal of Clinical Nutrition. 114:1360-1370
Background S-adenosylmethionine (SAM) as methyl donors participates in methylation and is converted into S-adenosylhomocysteine (SAH), which is a precursor of homocysteine. Increased plasma SAH and homocysteine are associated with increased risk of c