Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yue Zhou"'
Publikováno v:
Brain Research Bulletin. 163:40-48
Melatonin (Mel) has neuroprotective effects; however, its roles in hypoxic-ischemic brain damage (HIBD) and the underlying mechanisms remain unknown. We aimed to explore its roles and mechanisms in a HIBD rat model. We found that exogenous Mel treatm
Publikováno v:
Neuroscience. 408:349-360
Oxysterol derived from cholesterol metabolism is involved in the inflammatory activation, and consequently in development of major chronic diseases. Multiple cytokines have been found to induce the expression of cholesterol metabolism-related enzymes
Autor:
Jifeng Wang, Hongyang Liu, Yifa Zhou, Junjie Hou, Zhangjing Niu, Yue Zhou, Wen Zhong, Fuquan Yang, Miaomiao Xue, Zonghong Li, Tao Xu
Publikováno v:
Molecular & Cellular Proteomics. 17:2119-2131
Chronic hyperlipidemia causes the dysfunction of pancreatic β-cells, such as apoptosis and impaired insulin secretion, which are aggravated in the presence of hyperglycemia. The underlying mechanisms, such as endoplasmic reticulum (ER) stress, oxida
Autor:
Xiangliang Tang, Mang Sun, Bin Tan, Shengde Wu, Xining Cao, Lianju Shen, Chunlan Long, Guanghui Wei, Yue Zhou, Yi Wei
Publikováno v:
Reproductive Toxicology. 81:17-27
As an environmental endocrine disruptor, Di-(2-ethylhexyl) phthalate (DEHP) affects blood-testis barrier (BTB)-associated proteins expression, which compromises BTB integrity and causes infertility. Notably, DEHP-induced testicular toxicity is relate
Autor:
Yan-Hong Zhou, Golam Jalal Ahammed, Xiao-Jian Xia, Hua Fang, Qihao Zhang, Yue Zhou, Jing-Quan Yu, Jiayin Hou
Publikováno v:
Environmental Pollution. 240:227-234
Brassinosteroids (BRs), a group of steroid phytohormones, are involved in multiple aspects of plant growth, development and stress responses. Despite recent studies on BRs-promoted pesticide metabolism in plants, the underlying mechanisms remain poor
Publikováno v:
Journal of Molecular and Cellular Cardiology. 121:266-276
Aims MiR-101a is reported to reduce post-infarction myocardial fibrosis through targeting c-FOS and TGFbr1. However the actions of miR-101a within the TGF-β signaling pathway are largely unknown. We demonstrate the mechanisms underlying mutual inhib
Autor:
Hongzhong Zhang, Yue Zhou, Hanfei Zhai, Rongrong Zhang, Xiaojing Zhang, Peng Zhaoxue, Siyu Zhao
Publikováno v:
Chemosphere. 200:412-418
In this study, the effect of Fe (II) on Anaerobic Ammonium Oxidation (ANAMMOX) process was investigated by step-wise increasing the Fe (II) in influent from 1 to 50 mg L−1. The nitrogen removal, biofilm property and the microbial community were ana
Publikováno v:
Biomedicine & Pharmacotherapy. 100:191-197
In the present study, the effects of Silybum marianum oil (SMO) on hepatic steatosis and oxidative stress were investigated during the development of nonalcoholic fatty liver disease (NAFLD) in high fat diet (HFD)-fed mice. The results showed that bo
Autor:
Sahar El-Mekkawy, Yoshihiro Hayakawa, Hiroaki Sakurai, Aki Kohyama, Akane Yamada, Yue Zhou, Satoru Yokoyama, Meselhy R. Meselhy, Yuji Matsuya, Amira A. Abdellatef
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss, Pp 111737-(2021)
Guggulsterone (GS) [4,17(20)-pregnadiene-3,16-dione], is the main active phytosterol constituent in guggul, the gum resin of Commiphora wightii (Arnott.) Bhand./Commiphora mukul Engl. tree, and is known for its medicinal effects. In this study, we re
Autor:
Jianhe Wei, Xiaopo Zhang, Fuchao Ma, Peng Guo, Chongming Wu, Quanyang Zhang, Xin Li, Shuai Wang, Yue Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 7, Iss 4, Pp 453-460 (2017)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Syringaresinol-4-O-β-d-glucoside (SSG), a furofuran-type lignan, was found to modulate lipid and glucose metabolism through an activity screen of lipid accumulation and glucose consumption, and was therefore considered as a promising candidate for t