Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Richard A, Koup"'
Publikováno v:
Methods. 154:118-124
Bispecific (bs) antibodies (Abs, bsAbs) are engineered immunoglobulins that contain two different antigen-binding sites in one molecule. bsAbs can be divided in two molecular formats; the IgG-like and non-IgG like. The structural elements of each for
Autor:
Celia Santos, Peter D. Kwong, Wing-Pui Kong, Baoshan Zhang, Yi Zhang, Amy Ransier, Robert T. Bailer, Kwanyee Leung, Richard A. Koup, Sam Darko, Tatsiana Bylund, Sandeep N. Narpala, Hadi M. Yassine, Ulrich Baxa, Cinque Soto, Rebecca A. Gillespie, M. Gordon Joyce, Julie E. Ledgerwood, Xueling Wu, Lawrence Shapiro, Madhu Prabhakaran, Adam K. Wheatley, Ivelin S. Georgiev, Kanta Subbarao, Chen-Hsiang Shen, Adrian B. McDermott, Gwo-Yu Chuang, Yumiko Matsuoka, Mangaiarkarasi Asokan, James C. Mullikin, Yaroslav Tsybovsky, Lingshu Wang, Paul V. Thomas, Jeffrey C. Boyington, Aliaksandr Druz, James R R Whittle, Daniel C. Douek, Eun Sung Yang, Mario Roederer, Masaru Kanekiyo, John R. Mascola, Barney S. Graham, Christopher R. Lees
Publikováno v:
Cell. 166:609-623
Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza vaccine trial, we sorted hemagglutinin cross-reactive memory B cells a
Autor:
Edward K Sarfo, Nicole A. Doria-Rose, Diana G. Scorpio, Raffaello Verardi, Sijy O'Dell, Michael Worobey, Yaroslav Tsybovsky, Kathryn E. Foulds, Gwo-Yu Chuang, Frank J. Arnold, Cheng Cheng, Tongqing Zhou, Li Ou, Hui Geng, Winston Wu, Kevin Liu, John Paul Todd, Alexander J. Jafari, Michael Chambers, Richard A. Koup, Adrian B. McDermott, Peter D. Kwong, Xuejun Chen, Kurt R. Hill, Hongying Duan, Rui Kong, Shuishu Wang, Vrc Production Program, Yiran Wang, Anita Changela, Lawrence Shapiro, Angela R. Corrigan, Kai Xu, John R. Mascola
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107981-(2020)
Summary: The HIV fusion peptide (FP) is a promising vaccine target. FP-directed monoclonal antibodies from vaccinated macaques have been identified that neutralize up to ∼60% of HIV strains; these vaccinations, however, have involved ∼1 year with
Autor:
John R. Mascola, Srinivas S. Rao, Takuya Yamamoto, Ulrich Baxa, Barney S. Graham, John Paul Todd, Jeffrey I. Cohen, Richard A. Koup, Michael G. Rossmann, Adrian B. McDermott, Gary J. Nabel, Geng Meng, M. Gordon Joyce, Wei Bu, Masaru Kanekiyo, James R R Whittle, Sandeep Narpala
Publikováno v:
Cell
SummaryEpstein-Barr virus (EBV) represents a major global health problem. Though it is associated with infectious mononucleosis and ∼200,000 cancers annually worldwide, a vaccine is not available. The major target of immunity is EBV glycoprotein 35