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Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):216-222
Lung surfactant protein B (SP-B) is a lipophilic protein critical to lung function at ambient pressure. KL(4) is a 21-residue peptide which has successfully replaced SP-B in clinical trials of synthetic lung surfactants. CD and FTIR measurements indi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (6):772-780
Solid-state NMR spectroscopic techniques were used to investigate the secondary structure of the transmembrane peptide phospholamban (TM-PLB), a sarcoplasmic Ca(2+) regulator. (13)C cross-polarization magic angle spinning spectra of (13)C carbonyl-la
Autor:
Dieter Baurecht, U. P. Fringeli, Gerald Reiter, René Hunziker, Alfred Karpfen, Beate I. Escher, Alexandra Simperler, Monira Siam
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):88-99
Trichlorophenols are weak acids of high hydrophobicity and are able to transport protons across the mitochondrial membrane. Thus the proton motive force is dissipated and the ATP production decreased. In situ Fourier Transform Infrared-Attenuated Tot
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (9):1976-1986
The membrane location of two fragments in two different K(+)-channels, the KvAP (from Aeropyrum pernix) and the HsapBK (human) corresponding to the putative "paddle" domains, has been investigated by CD, fluorescence and NMR spectroscopy. Both domain
Autor:
Michael E. Herbig, Ursina Fromm, Annette G. Beck-Sickinger, Jeannine Leuenberger, Hans P. Merkle, Ulrike Krauss
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):197-211
Cell-penetrating peptides (CPPs) are able to translocate problematic therapeutic cargoes across cellular membranes. The exact mechanisms of translocation are still under investigation. However, evidence for endocytic uptake is increasing. We investig
Autor:
Ronald G. Larson, Senthil K. Kandasamy
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (9):1274-1284
The effect of salt on the binding of the antimicrobial peptide magainin to POPC lipid bilayers is studied by 40–50 ns molecular dynamics simulations of a POPC bilayer in the presence of different concentrations of Na+ and Cl− ions, corresponding
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):213-221
Cardiolipin (CL) is a phospholipid found in the energy-transducing membranes of bacteria and mitochondria and it is thought to be involved in relevant biological processes as apoptosis. In this work, the mixing properties of CL and 1-palmitoyl-2-oleo
Autor:
Ariel Alcides Petruk, Maria Rosaria Coscia, Sonia Varriale, Umberto Oreste, Antonello Merlino, Lelio Mazzarella
Publikováno v:
Elsevier science 1828 (2013): 2637–2645. doi:10.1016/J.BBAMEM.2013.07.019
info:cnr-pdr/source/autori:Ariel Alcides Petruka, Sonia Varriale, Maria Rosaria Coscia, Lelio Mazzarellab, Antonello Merlino, Umberto Oreste./titolo:THE STRUCTURE OF THE CD3 ZZ TRANSMEMBRANE DIMER IN POPC AND RAFT-LIKE LIPID BILAYER: A MOLECULAR DYNAMICS APPROACH./doi:10.1016%2FJ.BBAMEM.2013.07.019/rivista:Elsevier science/anno:2013/pagina_da:2637/pagina_a:2645/intervallo_pagine:2637–2645/volume:1828
info:cnr-pdr/source/autori:Ariel Alcides Petruka, Sonia Varriale, Maria Rosaria Coscia, Lelio Mazzarellab, Antonello Merlino, Umberto Oreste./titolo:THE STRUCTURE OF THE CD3 ZZ TRANSMEMBRANE DIMER IN POPC AND RAFT-LIKE LIPID BILAYER: A MOLECULAR DYNAMICS APPROACH./doi:10.1016%2FJ.BBAMEM.2013.07.019/rivista:Elsevier science/anno:2013/pagina_da:2637/pagina_a:2645/intervallo_pagine:2637–2645/volume:1828
Plasma membrane lipids significantly affect assembly and activity of many signaling networks. The present work is aimed at analyzing, by molecular dynamics simulations, the structure and dynamics of the CD3 ζζ dimer in palmitoyl-oleoyl-phosphatidyl