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Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
Viroporins comprise a family of non-structural proteins that play significant and diverse roles during the replication cycle of many animal viruses. Consequently, they have become promising targets for inhibitory drug and vaccine development. Structu
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
The 63 amino acid polytopic membrane protein, p7, encoded by hepatitis C virus (HCV) is involved in the modulation of electrochemical gradients across membranes within infected cells. Structural information relating to p7 from multiple genotypes has
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
Membrane fusion and fission underlie two limiting steps of enveloped virus replication cycle: access to the interior of the host-cell (entry) and dissemination of viral progeny after replication (budding), respectively. These dynamic processes procee
Autor:
Liao Y. Chen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (8):1786-1793
Among aquaglyceroporins that transport both water and glycerol across the cell membrane, Escherichia coli glycerol uptake facilitator (GlpF) is the most thoroughly studied. However, one question remains: Does glycerol modulate water permeation? This
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):348-354
Distributions of lysopalmitoylphosphatidylcholine (LPPC), palmitic acid (PA) and their 1:1 mixtures between water and dipalmitoylphosphatidylcholine (DPPC) bilayer were determined using a fluorescence probe that selectively detects only the solutes i
Autor:
Gerald W. Feigenson
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):47-52
Understanding the phase behavior of biological membranes is helped by the study of more simple systems. Model membranes that have as few as 3 components exhibit complex phase behavior that can be well described, providing insight for biological membr
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):216-222
Lung surfactant protein B (SP-B) is a lipophilic protein critical to lung function at ambient pressure. KL(4) is a 21-residue peptide which has successfully replaced SP-B in clinical trials of synthetic lung surfactants. CD and FTIR measurements indi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (10):2635-2645
The oxygen permeability coefficient across the membrane made of the total lipid extract from the plasma membrane of calf lens was estimated from the profile of the oxygen transport parameter (local oxygen diffusion-concentration product) and compared
Autor:
Alexander I. Greenwood, Stephanie Tristram-Nagle, Richard M. Epand, John F. Nagle, Thalia T. Mills, Jianjun Pan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (4):1120-1130
This study uses low-angle (LAXS) and wide-angle (WAXS) X-ray synchrotron scattering, volume measurements and thin layer chromatography to determine the structure and interactions of SOPC, SOPC/cholesterol mixtures, SOPC/peptide and SOPC/cholesterol/p
Autor:
Javier L. Baylon, Emad Tajkhorshid, Aditi Das, Yelena V. Grinkova, Jared A. Hammernik, Daryl D. Meling, Daniel R. McDougle, Amogh Kambalyal
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (10):2460-2470
CYP2J2 epoxygenase is an extrahepatic, membrane bound cytochrome P450 (CYP) that is primarily found in the heart and mediates endogenous fatty acid metabolism. CYP2J2 interacts with membranes through an N-terminal anchor and various non-contiguous hy