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Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. (3):391-399
Oxidative stress promotes endothelial cell senescence and endothelial dysfunction, important early steps in atherogenesis. To investigate potential antioxidant effects of IGF-1 we treated human aortic endothelial cells (hAECs) with 0–100 ng/mL IGF-
Publikováno v:
Biochimica et Biophysica Acta
Astrocytes play a crucial role in proper iron handling within the central nervous system. This competence can be fundamental, particularly during neuroinflammation, and neurodegenerative processes, where an increase in iron content can favor oxidativ
Autor:
Shirley ShiDu Yan, Heng Du
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. (1):198-204
Amyloid beta (Abeta) plays a critical role in the pathophysiology of Alzheimer's disease. Increasing evidence indicates mitochondria as an important target of Abeta toxicity; however, the effects of Abeta toxicity on mitochondria have not yet been fu