Zobrazeno 1 - 10
of 126
pro vyhledávání: ''
Autor:
Keith W. Caldecott, Zhengping Shao, Kouji Hirota, Annie A. Demin, Shan Zha, Jan Brazina, Hana Hanzlikova, Shunichi Takeda, Marek Adamowicz, Masataka Tsuda, William Gittens, Richard Hailstone, Ilona Kalasova, Hiroyuki Sasanuma
Publikováno v:
Molecular Cell
Summary Mammalian DNA base excision repair (BER) is accelerated by poly(ADP-ribose) polymerases (PARPs) and the scaffold protein XRCC1. PARPs are sensors that detect single-strand break intermediates, but the critical role of XRCC1 during BER is unkn
Autor:
Lorenzo Botta, Fabiola Ciccosanti, Francesca Colavita, Gian Maria Fimia, Fabrizio Manetti, Martina Di Rienzo, Concetta Castilletti, Alessandra Romagnoli, Giuseppe Ippolito, Annalaura Brai, Giulia Refolo, Mauro Piacentini, Maria Rosaria Capobianchi, Chiara Agrati
Publikováno v:
Antiviral Research
COVID-19 is currently a highly pressing health threat and therapeutic strategies to mitigate the infection impact are urgently needed. Characterization of the SARS-CoV-2 interactome in infected cells may represent a powerful tool to identify cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217b3ebf478516ed3ffc9ca4461d86b2
http://hdl.handle.net/11573/1572508
http://hdl.handle.net/11573/1572508
Autor:
Nikos K. Karamanos, Maurizio Onisto, Marco Franchi, Eirini Riti, Zoi Piperigkou, Valentina Masola
Publikováno v:
Matrix Biology Plus, Vol 6, Iss, Pp 100026-(2020)
Matrix Biology Plus
Matrix Biology Plus
Cancer cell invasion into the surrounding extracellular matrix (ECM) takes place when cell-cell junctions are disrupted upon epithelial-to-mesenchymal transition (EMT). Both cancer cell-stroma and cell-cell crosstalk are essential to support the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26776a5aa1dcdff99a065ddaa8f649c
http://hdl.handle.net/11577/3352417
http://hdl.handle.net/11577/3352417
Autor:
Roberto Gambari, Elisabetta D'Aversa, Alessia Finotti, Giulia Breveglieri, Monica Borgatti, Jessica Gasparello
Publikováno v:
International Immunopharmacology
One of the major clinical features of COVID-19 is a hyperinflammatory state, which is characterized by high expression of cytokines (such as IL-6 and TNF-α), chemokines (such as IL-8) and growth factors and is associated with severe forms of COVID-1
Autor:
Ping Jiang, Xianwei Wang, Mi Wang, Zhongbao Song, Yufeng Li, Zhi-Jian Wang, Qianyu Liu, Juan Bai, Chang-Meng Xu
Publikováno v:
Virus Research
Highlights • Vimentin was a restriction factor on the replication of PCV2 in PK-15 cells. • Vimentin could interact with PCV2 Cap protein during PCV2 infection. • Vimentin affected NF-κB signaling pathways during PCV2 infection. • Vimentin u
Autor:
Wei Li
Publikováno v:
Biophysical Chemistry
One notable feature of the SARS-CoV-2 genome, the spike (S) protein of SARS-CoV-2 has a polybasic furin cleavage site (FCS) at its S1-S2 boundary through the insertion of 12 nucleotides encoding four amino acid residues PRRA. Quite intriguingly, this
Autor:
Lucia Micale, Gian Maria Fimia, Gabriella Maria Squeo, Carmela Fusco, Barbara Mandriani, Eva Sjøttem, Martina Di Rienzo, Dario Cocciadiferro, Natascia Malerba, Bartolomeo Augello, Giuseppe Merla, Ashish Jain, Maria Teresa Pellico, Terje Johansen
Autophagy is a catabolic process needed for maintaining cell viability and homeostasis in response to numerous stress conditions. Emerging evidence indicates that the ubiquitin system has a major role in this process. TRIMs, an E3 ligase protein fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8543169120d73e5a9cde29475041d
http://hdl.handle.net/11573/1410993
http://hdl.handle.net/11573/1410993
Publikováno v:
Virus Research
Highlights • Coronavirus replication induces ER stress and the unfolded protein response (UPR). • Several coronavirus proteins modulate coronavirus-induced UPR. • During coronavirus infection, PERK is pro-apoptotic and IRE1 is anti-apoptotic.
Publikováno v:
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Universidad del Rosario
instacron:Universidad del Rosario
Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Analysis of our Plasmodium falciparum malaria parasite peptides’ 1H-NMR database in the search for H-bonds and ?-interactions led us to correlate their presence or absence with a peptide's particular immunological behavior. It was concluded that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9415296bde3e1826b4f21414e0b019b6
https://repository.urosario.edu.co/handle/10336/23516
https://repository.urosario.edu.co/handle/10336/23516
Climate change and increasing temperatures are global concerns. Camel (Camelus dromedarius) lives most of its life under high environmental stress in the desert and represent ideal model for studying desert adaptation among mammals. Catalase plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839d01e9296cb52ecc93d1db649c9b16
https://hdl.handle.net/20.500.12403/453
https://hdl.handle.net/20.500.12403/453