Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Udaiyappan Janakiraman"'
Autor:
Chinnasamy Dhanalakshmi, Udaiyappan Janakiraman, Aubin Moutal, Kohji Fukunaga, Rajesh Khanna, Mark A. Nelson
Publikováno v:
Neurobiology of Disease, Vol 149, Iss , Pp 105224- (2021)
The TATA-box binding protein associated factor 1 (TAF1) is part of the TFIID complex that plays a key role during the initiation of transcription. Variants of TAF1 are associated with neurodevelopmental disorders. Previously, we found that CRISPR/Cas
Externí odkaz:
https://doaj.org/article/6560230f9d8d4f378bb584cb8eece685
Autor:
Udaiyappan Janakiraman, Chinnasamy Dhanalakshmi, Jie Yu, Aubin Moutal, Lisa Boinon, Kohji Fukunaga, Rajesh Khanna, Mark A. Nelson
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 105006- (2020)
T-type calcium channels, in the central nervous system, are involved in the pathogenesis of many neurodegenerative diseases, including TAF1 intellectual disability syndrome (TAF1 ID syndrome). Here, we evaluated the efficacy of a novel T-type Ca2+ ch
Externí odkaz:
https://doaj.org/article/1b01b6572c2646a2a8f997925067b9a0
Autor:
Udaiyappan Janakiraman, Jie Yu, Aubin Moutal, Dhanalakshmi Chinnasamy, Lisa Boinon, Shelby N. Batchelor, Annaduri Anandhan, Rajesh Khanna, Mark A. Nelson
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
TAF1/MRSX33 intellectual disability syndrome is an X-linked disorder caused by loss-of-function mutations in the TAF1 gene. How these mutations cause dysmorphology, hypotonia, intellectual and motor defects is unknown. Mouse models which have embryon
Externí odkaz:
https://doaj.org/article/9296e3a70d0f4deda2ad7f38e7164540
Autor:
Mark A. Nelson, Kohji Fukunaga, Udaiyappan Janakiraman, Chinnasamy Dhanalakshmi, Aubin Moutal, Lisa Boinon, Jie Yu, Rajesh Khanna
Publikováno v:
Neurobiology of Disease, Vol 143, Iss, Pp 105006-(2020)
Neurobiol Dis
Neurobiol Dis
T-type calcium channels, in the central nervous system, are involved in the pathogenesis of many neurodegenerative diseases, including TAF1 intellectual disability syndrome (TAF1 ID syndrome). Here, we evaluated the efficacy of a novel T-type Ca2+ ch