Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sinu, P."'
Autor:
Kabir Sardana, MD, DNB, Surabhi Sinha, MD, DNB, Amlendu Yadav, MD, Desh Deepak, MD, Sanjeet Panesar, MBBS, MD, Sinu Rose Mathachan, MD, DNB
Publikováno v:
JAAD International, Vol 8, Iss , Pp 10-15 (2022)
Background: Varied cutaneous manifestations of COVID-19 have been described, but most studies are based on photographic or application-based observations, without a direct observed-based evaluation by dermatologists. Objective: To study the types of
Externí odkaz:
https://doaj.org/article/5750f7477c6641df9d6676cdc884a70e
Autor:
Sinu P. John, Anju Singh, Jing Sun, Makheni Jean Pierre, Lulwah Alsalih, Crystal Lipsey, Ziann Traore, Shenavia Balcom-Luker, Clinton J. Bradfield, Jian Song, Tovah E. Markowitz, Margery Smelkinson, Marc Ferrer, Iain D.C. Fraser
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111441- (2022)
Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify sev
Externí odkaz:
https://doaj.org/article/06f3747de2c641e5be2280b4ab2b1065
Akademický článek
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Publikováno v:
Journal of Asia-Pacific Biodiversity, Vol 12, Iss 2, Pp 311-315 (2019)
Predation is an important selective force that determines breeding success in all animals. Animals adopt a range of antipredatory strategies to overcome predation pressure in the breeding site, which is also a major predation ground. Birds mitigate t
Externí odkaz:
https://doaj.org/article/c870d70072d743c39e9e54af711e3962
Akademický článek
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Autor:
Sinu P. John, Jing Sun, Rebecca J. Carlson, Binh Cao, Clinton J. Bradfield, Jian Song, Margery Smelkinson, Iain D.C. Fraser
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 95-106.e6 (2018)
Summary: Activation of the TLR4 signaling pathway by lipopolysaccharide (LPS) leads to induction of both inflammatory and interferon-stimulated genes, but the mechanisms through which these coordinately activated transcriptional programs are balanced
Externí odkaz:
https://doaj.org/article/1d901e420dc14605a801e970fd481093
Autor:
George Savidis, William M. McDougall, Paul Meraner, Jill M. Perreira, Jocelyn M. Portmann, Gaia Trincucci, Sinu P. John, Aaron M. Aker, Nicholas Renzette, Douglas R. Robbins, Zhiru Guo, Sharone Green, Timothy F. Kowalik, Abraham L. Brass
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 232-246 (2016)
The flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we completed orthologous functional genomic screens using RNAi and CRISPR/Cas
Externí odkaz:
https://doaj.org/article/69f8be84e6a64743bebffa1e93abc54a
Autor:
Jian Zhu, Teresa Davoli, Jill M. Perriera, Christopher R. Chin, Gaurav D. Gaiha, Sinu P. John, Frederic D. Sigiollot, Geng Gao, Qikai Xu, Hongjing Qu, Thomas Pertel, Jennifer S. Sims, Jennifer A. Smith, Richard E. Baker, Louise Maranda, Aylwin Ng, Stephen J. Elledge, Abraham L. Brass
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 752-766 (2014)
RNAi screens have implicated hundreds of host proteins as HIV-1 dependency factors (HDFs). While informative, these early studies overlap poorly due to false positives and false negatives. To ameliorate these issues, we combined information from the
Externí odkaz:
https://doaj.org/article/b80c3f7209634aecb2d5e9756a0d87f6
Autor:
Tsai-Yu Lin, Christopher R. Chin, Aaron R. Everitt, Simon Clare, Jill M. Perreira, George Savidis, Aaron M. Aker, Sinu P. John, David Sarlah, Erick M. Carreira, Stephen J. Elledge, Paul Kellam, Abraham L. Brass
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 895-908 (2013)
The IFITMs inhibit influenza A virus (IAV) replication in vitro and in vivo. Here, we establish that the antimycotic heptaen, amphotericin B (AmphoB), prevents IFITM3-mediated restriction of IAV, thereby increasing viral replication. Consistent with
Externí odkaz:
https://doaj.org/article/f5e7ef117daf469eac6a2181bd278b4f
Autor:
Jian Zhu, Gaurav D. Gaiha, Sinu P. John, Thomas Pertel, Christopher R. Chin, Geng Gao, Hongjing Qu, Bruce D. Walker, Stephen J. Elledge, Abraham L. Brass
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 807-816 (2012)
HIV-1 depends on many host factors for propagation. Other host factors, however, antagonize HIV-1 and may have profound effects on viral activation. Curing HIV-1 requires the reduction of latent viral reservoirs that remain in the face of antiretrovi
Externí odkaz:
https://doaj.org/article/c79ff68d377844489f7b58a07affe3be