Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ron H.N. van Schaik"'
Autor:
Stefan A.J. Buck, Marinda Meertens, Frederiek M.F. van Ooijen, Esther Oomen-de Hoop, Evert de Jonge, Marieke J.H. Coenen, Andries M. Bergman, Stijn L.W. Koolen, Ronald de Wit, Alwin D.R. Huitema, Ron H.N. van Schaik, Ron H.J. Mathijssen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115890- (2023)
Extragonadal androgens play a pivotal role in prostate cancer disease progression on androgen receptor signaling inhibitors (ARSi), including abiraterone and enzalutamide. We aimed to investigate if germline variants in genes involved in extragonadal
Externí odkaz:
https://doaj.org/article/6d3d5ec4ff3b487a8575fbe70cc76c22
Autor:
G.D. Marijn Veerman, Rene J. Boosman, Merel Jebbink, Esther Oomen-de Hoop, Anthonie J. van der Wekken, Idris Bahce, Lizza E.L. Hendriks, Sander Croes, Christi M.J. Steendam, Evert de Jonge, Stijn L.W. Koolen, Neeltje Steeghs, Ron H.N. van Schaik, Egbert F. Smit, Anne-Marie C. Dingemans, Alwin D.R. Huitema, Ron H.J. Mathijssen
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101955- (2023)
Summary: Background: Central nervous system (CNS) metastases are present in approximately 40% of patients with metastatic epidermal growth factor receptor-mutated (EGFRm+) non-small cell lung cancer (NSCLC). The EGFR-tyrosine kinase inhibitor osimert
Externí odkaz:
https://doaj.org/article/3a9954ccf1454c0c889fa14273839a4e
Autor:
Bram C. Agema, Sanne M. Buijs, Sebastiaan D.T. Sassen, Thomas E. Mürdter, Mathias Schwab, Birgit C.P. Koch, Agnes Jager, Ron H.N. van Schaik, Ron H.J. Mathijssen, Stijn L.W. Koolen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114369- (2023)
Background: Tamoxifen is important in the adjuvant treatment of breast cancer. A plasma concentration of the active metabolite endoxifen of > 16 nM is associated with a lower risk of breast cancer-recurrence. Since inter-individual variability is hig
Externí odkaz:
https://doaj.org/article/2396b06ab4c94959a7fe50d0e9284b90
Autor:
Mirjam de With, Leni van Doorn, Demi C. Maasland, Tessa A.M. Mulder, Esther Oomen-de Hoop, Bianca Mostert, Marjolein Y.V. Homs, Samira El Bouazzaoui, Ron H.J. Mathijssen, Ron H.N. van Schaik, Sander Bins
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114232- (2023)
Aim of the study: Occurrence of hand-foot syndrome (HFS) during capecitabine treatment often results in treatment interruptions (26 %) or treatment discontinuation (17 %), and can severely decrease quality of life. In this study, we investigated whet
Externí odkaz:
https://doaj.org/article/22d712ca5f2d4b6f9d5ea8fc0cd5da1f
Autor:
Milan Macek, Ming T.M. Lee, Vita Dolzan, Christina Mitropoulou, David Neil Cooper, Athanassios Vozikis, Alessio Squassina, Federico Innocenti, Barbara Prainsack, Ron H.N. van Schaik, Bauke Ylstra, George P. Patrinos, Domenica Taruscio, Marc S. Williams, Effy Vayena, Paolo Fortina, Angela Brand, Fahd Al-Mulla, Konstantinos Mitropoulos
Publikováno v:
Genomic Medicine in Emerging Economies: Genomics for Every Nation, 173-188
STARTPAGE=173;ENDPAGE=188;TITLE=Genomic Medicine in Emerging Economies: Genomics for Every Nation
Cooper, D N, Mitropoulou, C, Brand, A, Dolzan, V, Fortina, P, Innocenti, F, Lee, M T M, Macek, M, Mitropoulos, K, Al-Mulla, F, Prainsack, B, van Schaik, R H, Squassina, A, Taruscio, D, Vayena, E, Vozikis, A, Williams, M S, Ylstra, B & Patrinos, G P 2018, The Genomic Medicine Alliance : A Global Effort to Facilitate the Introduction of Genomics into Healthcare in Developing Nations . in Genomic Medicine in Emerging Economies: Genomics for Every Nation . Genomic Medicine in Emerging Economies: Genomics for Every Nation, Elsevier, pp. 173-188 . https://doi.org/10.1016/B978-0-12-811531-2.00008-4
Cooper, D N, Mitropoulou, C, Brand, A, Dolzan, V, Fortina, P, Innocenti, F, Lee, M T M, Macek, M, Mitropoulos, K, Al-Mulla, F, Prainsack, B, van Schaik, R H, Squassina, A, Taruscio, D, Vayena, E, Vozikis, A, Williams, M S, Ylstra, B & Patrinos, G P 2018, The genomic medicine alliance: A global effort to facilitate the introduction of genomics into healthcare in developing nations . in Genomic Medicine in Emerging Economies: Genomics for Every Nation . Genomic Medicine in Emerging Economies: Genomics for Every Nation, Elsevier, pp. 173-188 . https://doi.org/10.1016/B978-0-12-811531-2.00010-2
STARTPAGE=173;ENDPAGE=188;TITLE=Genomic Medicine in Emerging Economies: Genomics for Every Nation
Cooper, D N, Mitropoulou, C, Brand, A, Dolzan, V, Fortina, P, Innocenti, F, Lee, M T M, Macek, M, Mitropoulos, K, Al-Mulla, F, Prainsack, B, van Schaik, R H, Squassina, A, Taruscio, D, Vayena, E, Vozikis, A, Williams, M S, Ylstra, B & Patrinos, G P 2018, The Genomic Medicine Alliance : A Global Effort to Facilitate the Introduction of Genomics into Healthcare in Developing Nations . in Genomic Medicine in Emerging Economies: Genomics for Every Nation . Genomic Medicine in Emerging Economies: Genomics for Every Nation, Elsevier, pp. 173-188 . https://doi.org/10.1016/B978-0-12-811531-2.00008-4
Cooper, D N, Mitropoulou, C, Brand, A, Dolzan, V, Fortina, P, Innocenti, F, Lee, M T M, Macek, M, Mitropoulos, K, Al-Mulla, F, Prainsack, B, van Schaik, R H, Squassina, A, Taruscio, D, Vayena, E, Vozikis, A, Williams, M S, Ylstra, B & Patrinos, G P 2018, The genomic medicine alliance: A global effort to facilitate the introduction of genomics into healthcare in developing nations . in Genomic Medicine in Emerging Economies: Genomics for Every Nation . Genomic Medicine in Emerging Economies: Genomics for Every Nation, Elsevier, pp. 173-188 . https://doi.org/10.1016/B978-0-12-811531-2.00010-2
The primary goal of genomic medicine is to make use of an individual's genomic information to support the clinical decision-making process. At present, several international organizations and research consortia exist, which aim to support the transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f847386313dfb30d8823e6b677f4531
https://research.vumc.nl/en/publications/e1e18d3e-cb51-40c4-86b4-ff96710469f3
https://research.vumc.nl/en/publications/e1e18d3e-cb51-40c4-86b4-ff96710469f3
Autor:
Geert J.L.H. van Leenders, Ron H.N. van Schaik, Xiaoye Zhu, Ewout W. Steyerberg, Monique J. Roobol, Fritz H. Schröder, Chris H. Bangma
Publikováno v:
European Urology, 63(4), 627-633. Elsevier
Background Inconclusive test results often occur after prostate-specific antigen (PSA)–based screening for prostate cancer (PCa), leading to uncertainty on whether, how, and when to repeat testing. Objective To develop and validate a prediction too
Pharmacogenetics is the discipline that translates information on genetic variability into prediction of the pharmacokinetics and pharmacodynamics effects of drugs. It was hoped that patients would receive the best drug in the correct dose and experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4462da1fd883085550994d05ce94ff
https://doi.org/10.1016/b978-0-12-800885-0.00005-9
https://doi.org/10.1016/b978-0-12-800885-0.00005-9
Autor:
Daniel Baron, Julia Beck, Stein Bergan, Heike Bittersohl, Sara Bremer, Sophie Brouard, Amitava Dasgupta, Magali Giral, Kamisha L. Johnson-Davis, Philipp Kanzow, Otto Kollmar, Loralie Langman, Gwendolyn A. McMillin, Michael C. Milone, Michael Oellerich, Jessica Schmitz, Ekkehard Schütz, Maria Shipkova, Werner Steimer, Teun van Gelder, Ron H.N. van Schaik, Nils Tore Vethe, Philip D. Walson, Eberhard Wieland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9fa260144757f0bb7e6552d6b6d19f
https://doi.org/10.1016/b978-0-12-800885-0.00019-9
https://doi.org/10.1016/b978-0-12-800885-0.00019-9
Autor:
Peter de Bruijn, Walter J. Loos, Anne-Joy M. de Graan, Mei-Ho Lam, Ron H.J. Mathijssen, Ron H.N. van Schaik, Erik A.C. Wiemer, Marianne van Fessem
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis, 54(2), 387-394. Elsevier
A rapid and sensitive ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method has been developed and validated for the simultaneous quantitative determination of dextromethorphan (DM) and its metabolites dextrorphan (DX),
Autor:
Helmut Klocker, Joep Kurstjens, Jasmin Bektic, Mark F. Wildhagen, Georg Bartsch, Chris H. Bangma, Ron H.N. van Schaik, Flip H. Jansen, Monique J. Roobol, Wolfgang Horninger
Publikováno v:
European Urology, 57(6), 921-927. Elsevier
Background: Novel markers for prostate cancer (PCa) detection are needed. Total prostate-specific antigen (tPSA) and percent free prostate-specific antigen (%fPSA = tPSA/fPSA) lack diagnostic specificity. Objective: To evaluate the use of prostate-sp