Zobrazeno 1 - 10
of 1 303
pro vyhledávání: '"Li Qian"'
Autor:
Paige Takasugi, Li Qian
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114085- (2024)
Bioengineering of a functional human heart continues to face many challenges, including the production of distinct cardiac cell types. Now, in Cell Stem Cell, Ye et al.1 develop AVC-like cardiomyocytes through timing- and concentration-specific activ
Externí odkaz:
https://doaj.org/article/3ec2ad9dd6224897ab33c46bac780f57
Autor:
Lei Chu, Li Qian, Yu Chen, Shengnan Duan, Ming Ding, Wu Sun, Wei Meng, Juanjuan Zhu, Quanyi Wang, Haiping Hao, Chen Wang, Shufang Cui
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113870- (2024)
Summary: The cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) is essential to elicit type I interferon cascade response; thus, the activity of cGAS must be strictly regulated to boost the antiviral innate immunity. Here, we report that cGAS is res
Externí odkaz:
https://doaj.org/article/4cc5a93da21b4583ba228463183b646c
Publikováno v:
Environment International, Vol 180, Iss , Pp 108232- (2023)
Blue carbon ecosystems (BCEs), located at the land-sea interface, provide critical ecological services including the buffering of anthropogenic pollutants. Understanding the interactions between trace element (TE) loads in BCEs and socioeconomic deve
Externí odkaz:
https://doaj.org/article/55b252bbfb42478aa930c7a06c9ff403
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102204- (2023)
Summary: Direct cardiac reprogramming refers to the conversion of fibroblasts into cardiomyocyte-like cells (iCMs) without going through an intermediate progenitor stage. Here, we present a protocol for direct cardiac reprogramming in mice using Ascl
Externí odkaz:
https://doaj.org/article/4ff20ddf6f9647baa40d1eb9ed661b8a
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 113-119 (2021)
Objective: To investigate the epidemiological dynamics, transmission patterns, and the clinical outcomes of Coronavirus disease 2019 (COVID-19) in familial cluster patients in Wuhan, China. Methods: Between January 22, 2020, and February 4, 2020, we
Externí odkaz:
https://doaj.org/article/6e355f208ffc47a3b990d921fa8ce4eb
Autor:
Jian Yang, Xiaoyan He, Li Qian, Binbin Zhao, Yajuan Fan, Fengjie Gao, Bin Yan, Feng Zhu, Xiancang Ma
Publikováno v:
EBioMedicine, Vol 78, Iss , Pp 103948- (2022)
Summary: Background: Childhood neurodevelopmental disorders, including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD), and Tourette syndrome (TS), comprise a major cause of health-related disabilities in children. How
Externí odkaz:
https://doaj.org/article/0f60a99358dc4c92800e1e606315a156
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102365- (2021)
Cardiovascular disease, until now, is still the leading cause of death in the United States. Due to the limited regenerative capacity of adult hearts, the damage caused by heart injury cannot be reversed and eventually progress into heart failure. In
Externí odkaz:
https://doaj.org/article/684e38437a054f62b735d17e3d6c583b
Publikováno v:
IDCases, Vol 23, Iss , Pp e00998- (2021)
Rabies remains endemic in China and continues to pose a major threat to public health with a nearly 100 % case fatality rate in humans. We confirmed a case of human rabies in Wuhan, in May 2018. The patient had got a dog bite wound 3 years before sym
Externí odkaz:
https://doaj.org/article/b0313460edec4b9badac726d0e4e720a
Publikováno v:
STAR Protocols, Vol 1, Iss 1, Pp 100010- (2020)
Summary: Direct cardiac reprogramming, the conversion of fibroblasts into cardiomyocyte-like cells (iCMs), is an attractive approach to heal the injured heart. Here we present a new approach to human cardiac reprogramming that utilizes a polycistroni
Externí odkaz:
https://doaj.org/article/2da7444fe0eb4975baa953138aa9853a
Autor:
Kimberly Sauls, Todd M. Greco, Li Wang, Meng Zou, Michelle Villasmil, Li Qian, Ileana M. Cristea, Frank L. Conlon
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1913-1922 (2018)
Summary: Direct reprogramming of fibroblasts into cardiomyocyte-like cells (iCM) holds great potential for heart regeneration and disease modeling and may lead to future therapeutic applications. Currently, application of this technology is limited b
Externí odkaz:
https://doaj.org/article/bac189e50a6e49b39170ff11cfe6e043