Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna M. Krichevsky"'
Autor:
Yanhong Zhang, Rosalia Rabinovsky, Zhiyun Wei, Rachid El Fatimy, Evgeny Deforzh, Bai Luan, Leonid Peshkin, Erik J. Uhlmann, Anna M. Krichevsky
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 265-275 (2023)
MicroRNA-10b (miR-10b) is an essential glioma driver and one of the top candidates for targeted therapies for glioblastoma and other cancers. This unique miRNA controls glioma cell cycle and viability via an array of established conventional and unco
Externí odkaz:
https://doaj.org/article/10a4b48db9e44e428e91f68ba2b1e1e6
Autor:
Ailiang Zeng, Zhiyun Wei, Rosalia Rabinovsky, Hyun Jung Jun, Rachid El Fatimy, Evgeny Deforzh, Ramil Arora, Yizheng Yao, Shun Yao, Wei Yan, Erik J. Uhlmann, Alain Charest, Yongping You, Anna M. Krichevsky
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101420- (2020)
Summary: Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant g
Externí odkaz:
https://doaj.org/article/affd28779865474595993f92557b0b03
Autor:
Zhiyun Wei, Xingjun Meng, Rachid El Fatimy, Bowen Sun, Dongmei Mai, Junfang Zhang, Ramil Arora, Ailiang Zeng, Pingyi Xu, Shaogang Qu, Anna M. Krichevsky, Dennis J. Selkoe, Shaomin Li
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
As the most common cause of progressive cognitive decline in humans, Alzheimer's disease (AD) has been intensively studied, but the mechanisms underlying its profound synaptic dysfunction remain unclear. Here we confirm that exposing wild-type mice t
Externí odkaz:
https://doaj.org/article/0555bcd7882b4d0fb94610581f5138af
Autor:
Rocco Lucero, Valentina Zappulli, Alessandro Sammarco, Oscar D. Murillo, Pike See Cheah, Srimeenakshi Srinivasan, Eric Tai, David T. Ting, Zhiyun Wei, Matthew E. Roth, Louise C. Laurent, Anna M. Krichevsky, Xandra O. Breakefield, Aleksandar Milosavljevic
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2065-2074.e4 (2020)
Summary: Glioblastoma (GBM) is characterized by aberrant vascularization and a complex tumor microenvironment. The failure of anti-angiogenic therapies suggests pathways of GBM neovascularization, possibly attributable to glioblastoma stem cells (GSC
Externí odkaz:
https://doaj.org/article/fc3e84da265140dfa24968d38eea26a6
Autor:
Erik R. Abels, Sybren L.N. Maas, Lisa Nieland, Zhiyun Wei, Pike See Cheah, Eric Tai, Christy-Joy Kolsteeg, Sophie A. Dusoswa, David T. Ting, Suzanne Hickman, Joseph El Khoury, Anna M. Krichevsky, Marike L.D. Broekman, Xandra O. Breakefield
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3105-3119.e7 (2019)
Summary: Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their microenvironment, communicating with and reprogramming surro
Externí odkaz:
https://doaj.org/article/77fbde4a03344664a5847ccb72526d8d
Autor:
Aron Gyuris, Jose Navarrete-Perea, Ala Jo, Simona Cristea, Shuang Zhou, Kyle Fraser, Zhiyun Wei, Anna M. Krichevsky, Ralph Weissleder, Hakho Lee, Steve P. Gygi, Al Charest
Publikováno v:
Cell Reports, Vol 27, Iss 13, Pp 3972-3987.e6 (2019)
Summary: Cancer extracellular vesicles (EVs) are highly heterogeneous, which impedes our understanding of their function as intercellular communication agents and biomarkers. To deconstruct this heterogeneity, we analyzed extracellular RNAs (exRNAs)
Externí odkaz:
https://doaj.org/article/5034af0a55cc44c5902e50df63b76e17
Autor:
Khairul I. Ansari, Daisuke Ogawa, Arun K. Rooj, Sean E. Lawler, Anna M. Krichevsky, Mark D. Johnson, E. Antonio Chiocca, Agnieszka Bronisz, Jakub Godlewski
Publikováno v:
Cell Reports, Vol 11, Iss 6, Pp 902-909 (2015)
In aggressive, rapidly growing solid tumors such as glioblastoma multiforme (GBM), cancer cells face frequent dynamic changes in their microenvironment, including the availability of glucose and other nutrients. These challenges require that tumor ce
Externí odkaz:
https://doaj.org/article/4fbd66bf70fc41a6bd5a2a571c94c805
Autor:
Wei Yan, Shun Yao, Zhiyun Wei, Rosalia Rabinovsky, Ramil Arora, Yizheng Yao, Anna M. Krichevsky, Alain Charest, Hyun Jung Jun, Evgeny Deforzh, Ailiang Zeng, Erik J. Uhlmann, Yongping You, Rachid El Fatimy
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101420-(2020)
iScience
iScience
Summary Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant gr