Zobrazeno 1 - 10
of 651
pro vyhledávání: '"Lipids"'
Autor:
Seiya Murakawa, Naoko Adachi, Takehiko Ueyama, Haruki Hirakawa, Kei Taguchi, Sohma Noguchi, Kana Harada, Norio Sakai, Masaya Asano, Izumi Hide, Shigeru Tanaka, Satoshi Kikkawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 1, Pp 187-195 (2022)
Flurbiprofen, a nonsteroidal anti-inflammatory drug, reportedly exhibits chemical chaperone activity. Herein, we investigated the role of flurbiprofen in regulating serotonin transporter (SERT) function via membrane trafficking. We used COS-7 cells t
Autor:
Evelyn Seelow, Eberhard Hildt, Denna Tabari, Kathrin Woytinek, David Heiler Martín, Catharina Scholl, Julia C. Stingl, Mira Choi, Benjamin Schmidt, Mirco Glitscher
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 159-180 (2021)
Cellular and Molecular Gastroenterology and Hepatology : CMGH 12, 159-180 (2021). doi:10.1016/j.jcmgh.2021.02.002
Cellular and Molecular Gastroenterology and Hepatology, 12(1):159-180
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology : CMGH 12, 159-180 (2021). doi:10.1016/j.jcmgh.2021.02.002
Cellular and Molecular Gastroenterology and Hepatology, 12(1):159-180
Cellular and Molecular Gastroenterology and Hepatology
Background and aims The Hepatitis E virus hijacks the endosomal system for its release. These structures are highly dependent on cholesterol. Hence, this study investigates the impact of HEV on cholesterol-metabolism, the effect of intracellular chol
Autor:
Alya Alruwaili, Leen Ghonem, Hadeel Alkofide, Aljwhara K. Alrasheed, Abdullah M Alhammad, Abdullah A. Alhifany, Khalid Eljaaly, Rehab Almutairi, Thamer A. Almangour, Aynaa Alsharidi
Publikováno v:
International Journal of Infectious Diseases, Vol 108, Iss, Pp 406-412 (2021)
Objective To compare the effectiveness and safety of aerosolized (AER) plus intravenous (IV) colistin with IV colistin alone in patients with nosocomial pneumonia (NP) due to multidrug-resistant (MDR) Gram-negative bacteria. Methods This was a retros
Autor:
Dan Chen, Tiantian Tan, Jiaxing Feng, Juan Zhao, Xu Song, Yao Fu, Ling Xiang, Qin Yang, Tao Gong
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 4, Pp 508-518 (2021)
Asian Journal of Pharmaceutical Sciences
Asian Journal of Pharmaceutical Sciences
Chondroitin sulfate-mediated albumin corona nanoparticles were readily prepared without any chemical reaction, and their active tumor targeting and therapeutic effects were examined. Negatively charged chondroitin sulfate (CS) and positively charged
Autor:
Sonoko Harada, Hitoshi Sasano, Tomohito Takeshige, Kazuhisa Takahashi, Fumihiko Makino, Ayako Ishimori, Hisaya Akiba, Jun Ito, Yuuki Sandhu, Kei Matsuno, Ryo Atsuta, Yoko Katsura, Norihiro Harada
Publikováno v:
Allergology International, Vol 70, Iss 3, Pp 343-350 (2021)
Background Previous reports have shown that pathogen-associated patterns (PAMPs) induce the production of interleukin (IL)-1β in macrophages. Moreover, studies using mouse models also suggest that chitin, which acts as a PAMP, induces adjuvant effec
Autor:
Esraa Aly, Willias Masocha
Publikováno v:
IBRO Neuroscience Reports, Vol 10, Iss, Pp 109-118 (2021)
IBRO Neuroscience Reports
IBRO Neuroscience Reports
Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP). There is a dearth of drugs or therapeutic modalities that can alleviate HIV-NP. Smoked cannabis has been report
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 6, Pp 609-620 (2019)
Asian Journal of Pharmaceutical Sciences
Asian Journal of Pharmaceutical Sciences
Cyclodextrin complexation is a wise strategy to enhance aqueous solubility of water-insoluble drugs. However, the aggregation mechanism of drug-cyclodextrin complexes is still unclear. This research aimed to investigate the molecular aggregation mech
Publikováno v:
Journal of Orthopaedic Translation, Vol 27, Iss, Pp 67-76 (2021)
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation
Objective The present work was aimed to evaluate the effect of valproic acid (VPA),Parathyroid hormone (1–34) (PTH)+VPA on Ti rods osseointegration in ovariectomized rats and further investigation of the possible mechanism. Methods The MC3T3-E1 c
Autor:
Mona Alonazi, Tarfa Albrahim
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111831-(2021)
Obesity is a global epidemic disease that is closely associated with various health problems as Diabetes mellitus, cardiovascular, and metabolic disorders. Lycopene (LYC), a red-colored carotenoid, has demonstrated various promising therapeutic effec
Autor:
Andreas G. Tzakos, Christina Papaemmanouil, Christos M. Chatzigiannis, Zoe Cournia, Sofia Kiriakidi, Thomas Mavromoustakos
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 110-120 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Hypertension, mediated by the Angiotensin II receptor type 1 (AT1R), is still the major cause of premature death despite the discovery of novel therapeutics, highlighting the importance of an in depth understanding of the drug
Hypertension, mediated by the Angiotensin II receptor type 1 (AT1R), is still the major cause of premature death despite the discovery of novel therapeutics, highlighting the importance of an in depth understanding of the drug