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Autor:
Cliff-Lawrence Ibeh, Samuel Shin, Eugenia Awuah Boadi, Bok-Eum Choi, Bidhan C. Bandyopadhyay, Sanjit K. Roy
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 531-548 (2022)
Proximal tubule (PT) transports most of the renal Ca2+, which was usually described as paracellular (passive). We found a regulated Ca2+ entry pathway in PT cells via the apical transient receptor potential canonical 3 (TRPC3) channel, which initiate
Autor:
Hikaru Saito, Yoichi Shimada, Koji Nozaka, Hiroyuki Tsuchie, Ryo Shoji, Kazunobu Abe, Naohisa Miyakoshi, Yuji Kasukawa, Chiaki Sato
Publikováno v:
Osteoporosis and Sarcopenia, Vol 7, Iss 4, Pp 121-126 (2021)
Osteoporosis and Sarcopenia
Osteoporosis and Sarcopenia
Objectives The purpose of this study is to investigate the stage of chronic kidney disease (CKD) in adenine-induced CKD model rats by serum analyses, and to examine bone mineral density (BMD), bone strength, and microstructure of trabecular and corti
Autor:
Hongyu Li, Yuhang Jiang, Yanfeng Wu, Huiyong Shen, Rujia Mi, Mengjun Ma, Yixuan Lu, Wen Yang, Xin Shen, Wenzhou Liu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 135-147 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
N-acetyltransferase 10 (NAT10) is the key enzyme for N4-acetylcytidine (ac4C) modification of mRNA, which participates in various cellular processes and is related to many diseases. Here, we explore the relationships among osteoblast differentiation,
Publikováno v:
Poultry Science, Vol 99, Iss 12, Pp 7084-7091 (2020)
Poultry Science
Poultry Science
Cage layer fatigue (CLF), which is commonly caused by calcium deficiency in the feed, leads to loss of structural bone and increase of bone fragility. In order to investigate the influence of low-calcium diets on bone quality and strength, histopatho
Autor:
Yohei Okubo
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 2, Pp 83-88 (2020)
Astrocytes generate robust intracellular Ca2+ signals that are assumed to be key regulators of astrocytic function. Among various Ca2+ mobilization mechanisms, Ca2+ release from the endoplasmic reticulum (ER) via the inositol 1,4,5-trisphosphate rece
Publikováno v:
Poultry Science, Vol 99, Iss 10, Pp 4914-4928 (2020)
Poultry Science
Poultry Science
Calcium has the capacity to interact with phytate-P to form Ca-phytate complexes and decrease the ability of exogenous phytase to degrade phytic acid. This study investigated the hypothesis that high dietary Ca would impair gut permeability, phytate
Autor:
Madalena M. Dias, Ana Cristina Pinheiro, Raquel Filipa Silva Gonçalves, Maria Filomena Barreiro, Andreia Ribeiro, Yaidelin A. Manrique, José Carlos B. Lopes
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Vitamin E is a lipophilic vitamin playing an essential role in human health. Due to oxidative instability, it presents fast degradation and bioactivity loss. In this study, vitamin E-loaded Pickering emulsions stabilized by nano-hydroxyapatite (n-HAp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc2482fbc35e51f784b356ec37719df
https://hdl.handle.net/1822/74593
https://hdl.handle.net/1822/74593
Autor:
Mariana Ford, Adriana Cassina, Nikita Peramsetty, Celia M. Santi, Rossana Sapiro, Juan J. Ferreira, Santiago Pietroroia, Pilar Irigoyen, Rafael Radi
Publikováno v:
Redox Biology, Vol 48, Iss, Pp 102176-(2021)
Redox Biology
Redox Biology
To fertilize an oocyte, sperm must undergo several biochemical and functional changes known as capacitation. A key event in capacitation is calcium influx through the cation channel of sperm (CatSper). However, the molecular mechanisms of capacitatio
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats
Autor:
Xiaofang Cheng, Ram Kumar Manthari, Jinming Wang, Huimiao Xu, Yangfei Zhao, Jiarong Yang, Junjiang Fan, Haojie Li, Jundong Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 226, Iss, Pp 112851-(2021)
Long-term excessive intake of fluoride (F) can cause osseous and non-osseous damage. The kidney is the main fluoride excretion organ of the body. This study aimed to explore whether dietary calcium (Ca) supplementation can alleviate kidney damage cau
Autor:
Alma Serrano, María Victoria Magallanes, Pedro Arango Sancho, María I. Luis Yanes, Víctor Manuel García Nieto, Germán Pérez Suárez
Publikováno v:
Nefrología (English Edition), Vol 40, Iss 2, Pp 190-196 (2020)
Introduction: There is much debate about whether idiopathic hypercalciuria (IH) affects kidney water management. For the first time in the literature, we carried out a longitudinal study of kidney water management (KWM) in patients diagnosed with IH