Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tamura A"'
Autor:
Masaki Ibe, Shinobu Tamura, Hideki Kosako, Yusuke Yamashita, Masamichi Ishii, Masaoh Tanaka, Hiroyuki Mishima, Akira Kinoshita, Sadahiro Iwabuchi, Shuhei Morita, Ko-ichiro Yoshiura, Shinichi Hashimoto, Naoyuki Nakao, Shigeaki Inoue
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 40, Iss , Pp 101107- (2024)
Schwannomatosis (SWN) is a rare genetic condition characterized by the risk of developing multiple benign peripheral nerve sheath tumors; however, the risk of developing malignant tumors in patients with SWN remains unclear. This study described the
Externí odkaz:
https://doaj.org/article/d6bb4a2d41504e64bfdb214d0388fb23
Autor:
Takaya Yamasaki, Akira Nishiyama, Nagomi Kurogi, Koutarou Nishimura, Shion Nishida, Daisuke Kurotaki, Tatsuma Ban, Jordan A. Ramilowski, Keiko Ozato, Atsushi Toyoda, Tomohiko Tamura
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114107- (2024)
Summary: The production of type 1 conventional dendritic cells (cDC1s) requires high expression of the transcription factor IRF8. Three enhancers at the Irf8 3′ region function in a differentiation stage-specific manner. However, whether and how th
Externí odkaz:
https://doaj.org/article/e862e22127f7412a8cc2e0bd07f50fc5
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113320- (2023)
Summary: In response to environmental cues, such as nutrient starvation, living organisms modulate gene expression through mechanisms involving histone modifications. Specifically, nutrient depletion inactivates the TOR (target of rapamycin) pathway,
Externí odkaz:
https://doaj.org/article/1fdb89b471944332834da69d4e4e12c3
Autor:
Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto, Daisuke Kurotaki, Koutarou Nishimura, Akira Nishiyama, Tomohiko Tamura, Takashi Kamatani, Tatsuhiko Tsunoda, Miyako Murakawa, Yasuhiro Asahina, Yoshihiro Hayashi, Hironori Harada, Yuka Harada, Asumi Yokota, Hideyo Hirai, Takao Seki, Makoto Kuwahara, Masakatsu Yamashita, Shigeyuki Shichino, Masato Tanaka, Kenichi Asano
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112165- (2023)
Summary: Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors, or growth factors remain elusive. In this study we find that Ym1+Ly6Chi monocytes,
Externí odkaz:
https://doaj.org/article/341ed34a2efa4c75818a16d64f9f1412
Autor:
Yukari Ando, Kazuya Kusama, Kazuhiro Tamura, Akito Kuroda, Takeshi Matsutani, Akihisa Matsuda
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100967-(2021)
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100967-(2021)
Obesity-induced endoplasmic reticulum (ER) stress contributes to low-grade chronic inflammation in adipose tissue and may cause metabolic disorders such as diabetes mellitus and dyslipidemia. Identification of high serpina A1 (alpha-1 antitrypsin, A1
Autor:
Kenji Inagaki, Takashi Tamura, Masaya Saito, Masaki Kitagawa, Yuya Matsumoto, Hitoshi Kusakabe, Katsumi Imada, Nanako Ito
Publikováno v:
Journal of Structural Biology: X, Vol 5, Iss, Pp 100044-(2021)
Journal of Structural Biology: X
Journal of Structural Biology: X
Graphical abstract
Highlights • The suppression mechanism of activity by propeptide remains unclear for most LAAOs. • The crystal structures of the LysOX precursor (prLysOX) have been determined. • The propeptide indirectly changes the act
Highlights • The suppression mechanism of activity by propeptide remains unclear for most LAAOs. • The crystal structures of the LysOX precursor (prLysOX) have been determined. • The propeptide indirectly changes the act
Autor:
Seigo Usuki, Noriko Tamura, Tomohiro Tamura, Shigeki Higashiyama, Kunikazu Tanji, Susumu Mitsutake, Asuka Inoue, Junken Aoki, Katsuyuki Mukai, Yasuyuki Igarashi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 17, Iss , Pp 132-138 (2019)
Previously, we proposed the following mechanism for konjac ceramide (kCer)-mediated neurite outgrowth inhibition: kCer binds to Nrp as a Sema3A agonist, resulting in Nrp1/PlexA complex formation and activation of the Sema3A signaling pathway to induc
Externí odkaz:
https://doaj.org/article/835577ace0db4a7ca050f7661c6f0a7a
Autor:
Yosuke Nakazawa, Miki Aoki, Yuri Doki, Naoki Morishita, Shin Endo, Noriaki Nagai, Megumi Funakoshi-Tago, Hiroomi Tamura
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100885- (2021)
Presbyopia is one of the most well-known diseases of the eye, predominantly affecting the adult population after 50 years’. Due to hardening of the lens and failure of accommodative change, patients lose the ability to focus on near objects. This e
Externí odkaz:
https://doaj.org/article/7fa02452be86457da63ad5c48ca11679
Autor:
Tatsuya Ohhata, Kazuki Yamazawa, Asuka Miura-Kamio, Saori Takahashi, Satoshi Sakai, Yuka Tamura, Chiharu Uchida, Kyoko Kitagawa, Hiroyuki Niida, Ichiro Hiratani, Hisato Kobayashi, Hiroshi Kimura, Anton Wutz, Masatoshi Kitagawa
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108912- (2021)
Summary: The fine-scale dynamics from euchromatin (EC) to facultative heterochromatin (fHC) has remained largely unclear. Here, we focus on Xist and its silencing initiator Tsix as a paradigm of transcription-mediated conversion from EC to fHC. In mo
Externí odkaz:
https://doaj.org/article/4b9d9f2858de47159760643071866902
Autor:
Masaki Kitagawa, Nanako Ito, Yuya Matsumoto, Masaya Saito, Takashi Tamura, Hitoshi Kusakabe, Kenji Inagaki, Katsumi Imada
Publikováno v:
Journal of Structural Biology: X, Vol 5, Iss , Pp 100044- (2021)
Harmuful proteins are usually synthesized as inactive precursors and are activated by proteolytic processing. l-Amino acid oxidase (LAAO) is a flavoenzyme that catalyzes the oxidative deamination of l-amino acid to produce a 2-oxo acid with ammonia a
Externí odkaz:
https://doaj.org/article/5f0a8e4c2a224ee8be3aba411458a521