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Autor:
Marike W. van Gisbergen, Erik Vegt, Joachim E. Wildberger, Felix M. Mottaghy, Catharina M.L. Zegers, Dirk De Ruysscher, Bart Reymen, Ala Yaromina, Philippe Lambin, Wouter van Elmpt, Ludwig Dubois, Aniek J.G. Even, Marco Das
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 21, Iss, Pp 49-55 (2020)
Clinical and Translational Radiation Oncology, 21, 49-55. Elsevier Ireland Ltd
Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology, 21, 49-55. Elsevier Ireland Ltd
Clinical and Translational Radiation Oncology
Highlights • Nitroglycerin didn’t improve overall survival of NSCLC patients. • The toxicity of combining nitroglycerin with standard treatment was mild. • Increased uptake of HX4 showed negative prognostic significance in NSCLC patients. •
Autor:
Cihan Kabukçu, Ozer Oztekin, Yasar Enli, Semin Fenkci, Ümit Çabuş, Veysel Fenkci, Vildan Caner
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 59, Iss 2, Pp 207-210 (2020)
Objective: Caspase-1 is implicated in several important inflammatory diseases and controls adipocyte differentiation and insulin sensitivity. Interleukin-10 (IL-10) is an anti-inflammatory cytokine and plays an important role in chronic inflammatory
Autor:
Ethan James Harris, Tom Thomas, Allen C. Lam, Nicole G. Chau, Roy B. Tishler, Grace M. Lee, Daniel Wonsoon Kim, Miranda B. Lam
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 2, Pp 301-310 (2020)
Advances in Radiation Oncology
Advances in Radiation Oncology
Background Microcystic adnexal carcinoma (MAC) is a rare, locally invasive skin neoplasm most commonly in the head and neck. MAC is routinely treated surgically and scant data is available regarding the role of definitive chemoradiotherapy (chemoRT)
Autor:
Hongwen Zhu, Fei Mao, Lei Wu, Yemi Gao, Qi Gong, Qinyuan Zhao, Linghao Hu, Jian Li, Xiaokang Li, Feng Hongxuan, Hai-Yan Zhang, Hu Zhou, Tao Lingxue
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 434-446 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Ischemic stroke is a severe disorder resulting from acute cerebral thrombosis. Here we demonstrated that post-ischemic treatment with ciclopirox olamine (CPX), a potent antifungal clinical drug, alleviated brain infarction, neurological deficits and
Autor:
Alma Serrano, María Victoria Magallanes, Pedro Arango Sancho, María I. Luis Yanes, Víctor Manuel García Nieto, Germán Pérez Suárez
Publikováno v:
Nefrología (English Edition), Vol 40, Iss 2, Pp 190-196 (2020)
Introduction: There is much debate about whether idiopathic hypercalciuria (IH) affects kidney water management. For the first time in the literature, we carried out a longitudinal study of kidney water management (KWM) in patients diagnosed with IH
Autor:
Thekla Cordes, Pedro Cabrales, Anne N. Murphy, Ajit S. Divakaruni, Alfredo Lucas, Christian M. Metallo
Publikováno v:
Molecular Metabolism, Vol 32, Iss, Pp 122-135 (2020)
Molecular Metabolism
Molecular Metabolism
Objectives Cerebral ischemia/reperfusion (IR) drives oxidative stress and injurious metabolic processes that lead to redox imbalance, inflammation, and tissue damage. However, the key mediators of reperfusion injury remain unclear, and therefore, the
Autor:
Suzanne E. Barbour, Tayleur D. White, Ying Gai Tusing, Christopher L. Cardona, Xiaoyong Lei, Sasanka Ramanadham, Abdulaziz Almutairi, Daniel J. Stephenson, Charles E. Chalfant, Margaret A. Park, Alexander J. Nelson
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 2, Pp 143-158 (2020)
Phospholipases A2 (PLA2s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can be metabolized to pro- or anti-inflammatory eicosanoids. Macrophages modulate inflammatory
Autor:
Qing-Hua Liu, Gangjian Qin, Yuan-Yuan Chen, Weiwei Chen, Jiapei Dai, Lu Xue, Yong-Bo Peng, Li-Qun Ma, Meng-Fei Yu, Xiao-Xue Zhao, Jinhua Shen, Ping Zhao
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 2, Pp 60-68 (2020)
The purpose of this study was to screen a bronchodilator from old drugs and elucidate the underlying mechanism. Paracetamol (acetaminophen) is a widely used analgesic and antipyretic drug. It has been reported that it inhibits the generation of prost
Autor:
Adriana Parra, Ana María Bertolotto, Isabel Coca, Claudia Devia, Adriana Montealegre, Nathalie Charpak
Publikováno v:
Anales de Pediatría (English Edition), Vol 92, Iss 2, Pp 79-87 (2020)
Introduction: Neonatal jaundice is common, especially in premature infants. Compliance treatment protocols with standard serum bilirubin curves force the clinician to separate the child from the mother after birth for phototherapy. The objective of t
Autor:
Raj Vuppalanchi, Mary F. Paine, Robin J. Marles, Steven J. Casper, Leonard B. Seeff, Bill J. Gurley, Hellen A. Oketch-Rabah, Tieraona Low Dog, Amy L. Roe, Jawad Ahmad, Scott A. Jordan, Gabriel I. Giancaspro, Andrew Stolz, Cynthia V. Rider, Christopher Koh, Richard Ko, Averell H. Sherker, Kan He, Jose Serrano, Robert J. Fontana, Herbert L. Bonkovsky, Víctor M. Navarro, Joseph M. Betz, Theertham P. Rao, Simona Rossi, Mahendra P. Kapoor
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 386-402 (2020)
Toxicology Reports
Toxicology Reports
As part of the United States Pharmacopeia’s ongoing review of dietary supplement safety data, a new comprehensive systematic review on green tea extracts (GTE) has been completed. GTEs may contain hepatotoxic solvent residues, pesticide residues, p