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Autor:
Maria Santos, Patrícia Burth, Caroline Azevedo Martins, Hugo C. Castro-Faria-Neto, Mauricio Younes-Ibrahim, Cassiano Felippe Gonçalves-de-Albuquerque, Mauro Velho Castro-Faria
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06420-(2021)
Heliyon
Heliyon
Human leptospirosis is an acute infectious zoonosis presenting specific lipid disorders. Previous in vitro studies showed both leptospira glycolipoprotein endotoxin, and high oleic acid levels were associated with Na/K-ATPase inhibition that is ampli
Publikováno v:
Heliyon
Heliyon, Vol 7, Iss 3, Pp e06444-(2021)
Heliyon, Vol 7, Iss 3, Pp e06444-(2021)
Sepsis-induces myocardial contractile dysfunction. We previously showed that whole body periodic acceleration (pGz), the sinusoidal motion of the supine body head-foot ward direction significantly improves survival and decreases microvascular permeab
Autor:
Faisal Abanumay, Abdullah bin Jurays, Khaled Alkethiri, Shahid Bashir, Syed Shahid Habib, Mohammed A AlDammas, Muhammad Iqbal, Tariq Almtroudi, Meshaal AlKhodheer
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06358-(2021)
Heliyon
Heliyon
Background Type 2 diabetes mellitus (T2DM) has been associated with impairment of cognitive functions. Since the majority of patients with diabetes in the Saudi population are between the ages of 40 and 69 years, it is crucial to ascertain whether th
Publikováno v:
Heliyon
Heliyon, Vol 7, Iss 3, Pp e06474-(2021)
Heliyon, Vol 7, Iss 3, Pp e06474-(2021)
Cardiomyopathy and pancreatic injury are health issues associated with type 2 diabetes mellitus (T2DM) and are characterized by elevated oxidative stress, inflammation and apoptosis. Melatonin (MLT) is a hormone with multifunctional antioxidant activ
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06287-(2021)
Heliyon
Heliyon
D-ribose-L-cysteine (DRLC) acts as a rate limiting substrate for the synthesis of glutathione (GSH). GSH deficiency has been linked to oxidative stress, hypertension and cardiovascular diseases. There are limited findings on the effects of DRLC in th
Autor:
Péter Klivényi, Edina Katalin Cseh, Zsuzsanna Bohár, Helga Polyák, Dénes Zádori, László Vécsei, József Toldi, Cecilia Rajda
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06124-(2021)
Heliyon
Heliyon
Background The kynurenine (KYN) pathway (KP) of the tryptophan (TRP) metabolism seems to play a role in the pathomechanism of multiple sclerosis (MS). Cuprizone (CPZ) treated animals develop both demyelination (DEM) and remyelination (REM) in lack of
Autor:
Kimio Watanabe, Eikan Mishima, Mayu Watanabe, Nobuyuki Takahashi, Takaaki Abe, Emiko Sato, Masaaki Nakayama
Publikováno v:
Heliyon
Heliyon, Vol 7, Iss 2, Pp e06221-(2021)
Heliyon, Vol 7, Iss 2, Pp e06221-(2021)
One third of the patients with chronic kidney disease (CKD) develop cognitive impairment, which is also an independent risk factor for mortality. However, the concise mechanism of cerebro-renal interaction has not been clarified. The present study ex
Autor:
Heloísa Aparecida Barbosa da Silva Pereira, Fabrício Soares Pereira, Juliana Sanches Trevizol, Valdecir Faria Ximenes, Aline Dionizio, Flávia Godoy Iano, Marília Afonso Rabelo Buzalaf, Tamara Teodoro Araujo
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e06028-(2021)
Heliyon
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Heliyon
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Fluoride (F) can induce changes in the expression of several liver proteins, most of them localized in the mitochondria and its effect is dose- and time-dependent. This study analyzed the effect of distinct F concentrations and exposure periods on th
Publikováno v:
Heliyon, Vol 6, Iss 12, Pp e05794-(2020)
Heliyon
Heliyon
Background Renal ischemia-reperfusion (renal I/R) injury may lead to acute kidney injury (AKI). After renal I/R, proinflammatory mediators cause immune cell infiltration and further injury. Milk fat globule-epidermal growth factor-factor 8 (MFG-E8) i
Publikováno v:
Heliyon, Vol 6, Iss 12, Pp e05655-(2020)
Heliyon
Heliyon
Introduction Diabetes mellitus is one of the rapidly growing global health concerns of the twenty-first century ravaging millions of individuals from all across the world. The aim of this study is to evaluate glycemic control status and its associate