Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tamura A"'
Autor:
Ryo Miyamoto, Takashi Kumasaka, Shigeyuki Matsumoto, Tohru Kataoka, Takashi Kawamura, Mitsugu Araki, Fumi Shima, Haruka Taniguchi-Tamura, Chiemi Tsuda, Yasushi Okuno
Publikováno v:
Biochemical and Biophysical Research Communications. 565:85-90
GTP-bound forms of Ras proteins (Ras•GTP) assume two interconverting conformations, "inactive" state 1 and "active" state 2. Our previous study on the crystal structure of the state 1 conformation of H-Ras in complex with guanosine 5'-(β, γ-imido
Publikováno v:
Biochemical and biophysical research communications. 527(2):539-544
Glycine, a non-essential amino acid, is involved in both angiogenesis and anti-angiogenesis. We hypothesized that glycine would exert dose-dependent different effects on angiogenesis. In this study, we investigated the effects of a broad range of con
Autor:
Susumu Mitsutake, Seigo Usuki, Yasuyuki Igarashi, Junken Aoki, Asuka Inoue, Kunikazu Tanji, Katsuyuki Mukai, Shigeki Higashiyama, Noriko Tamura, Tomohiro Tamura
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 17, Iss, Pp 132-138 (2019)
Biochemistry and Biophysics Reports, Vol 17, Iss, Pp 132-138 (2019)
Previously, we proposed the following mechanism for konjac ceramide (kCer)-mediated neurite outgrowth inhibition: kCer binds to Nrp as a Sema3A agonist, resulting in Nrp1/PlexA complex formation and activation of the Sema3A signaling pathway to induc
Autor:
Akihiro Tamura, Kenji Kishimoto, Nobuyuki Yamamoto, Yoshiyuki Kosaka, Toshiaki Ishida, Takeshi Mori, Khin Kyae Mon Thwin, Noriyuki Nishimura, Atsuro Saito, Suguru Uemura, Aiko Kozaki, Daiichiro Hasegawa, Kazumoto Iijima, Nanako Nino, Satoru Takafuji, Kyaw San Lin
Publikováno v:
Journal of Molecular Diagnostics. 22(2):236-246
Monitoring of several sets of neuroblastoma-associated mRNAs (NB-mRNAs) by real-time quantitative PCR (qPCR) can be used to evaluate minimal residual disease in NB patients. Droplet digital PCR (ddPCR) is an adaption of qPCR that potentially provides
Autor:
China Nagano, Toshiaki Ishida, Daiichiro Hasegawa, Atsuro Saito, Yoshiyuki Kosaka, Khin Kyae Mon Thwin, Nobuyuki Yamamoto, Kyaw San Lin, Kazumoto Iijima, Naoko Nakatani, Nanako Nino, Takeshi Mori, Satoru Takafuji, Suguru Uemura, Noriyuki Nishimura, Akihiro Tamura
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101019-(2021)
Translational Oncology
Translational Oncology
Highlights • Bone marrow is the most frequent site of metastasis and relapse for neuroblastoma. • Minimal residual disease has been identified in bone marrow and peripheral blood (BM-MRD and PB-MRD) by quantifying several sets of neuroblastoma-as
Autor:
Yukari Ando, Kazuya Kusama, Kazuhiro Tamura, Akito Kuroda, Takeshi Matsutani, Akihisa Matsuda
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100967-(2021)
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100967-(2021)
Obesity-induced endoplasmic reticulum (ER) stress contributes to low-grade chronic inflammation in adipose tissue and may cause metabolic disorders such as diabetes mellitus and dyslipidemia. Identification of high serpina A1 (alpha-1 antitrypsin, A1
Autor:
Kanako Kobayashi, Satomu Morita, Keita Sakurai, Ken-ichi Yoshida, Mayumi Kataoka, Yoshiteru Tamura, Hideyuki Maeda, Hidenori Yoshizawa, Keiko Matsuno
Publikováno v:
Human Pathology: Case Reports, Vol 23, Iss, Pp 200483-(2021)
On a mid-summer day, a middle-aged man with severe pectus excavatum died unexpectedly in his bed one to two weeks after the onset of dyspnea, which had been followed by bedrest and restricted drinking and eating. Computed tomography (CT) and autopsy
Autor:
Masayoshi Takahashi, Hiroyuki Kawaguchi, Yasumasa Yoshiyama, Akira Homma, Tatsuo Kagimura, Masato Kobayashi, Kazuma Nishimura, Takayuki Sato, Hiroshi Matsuzawa, Kaoru Tamura, Takayuki Saito, Yosuke Tachibana, Yu Nakamura, Mitsunori Watanabe, Naoki Kubota
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Introduction Symptomatic anti-Alzheimer's disease (AD) drugs have been commonly used for the treatment of AD. Knowing the natural courses of patients with AD on placebo is highly relevant for clinicians to understand their efficacy and for investigat
Autor:
Kei Miyakawa, Takaji Wakita, Sundararaj Stanleyraj Jeremiah, Daisuke Kurotaki, Hironori Nishitsuji, Satoko Matsunaga, Sayaka Shizukuishi, Koichi Watashi, Hirokazu Kimura, Kunitada Shimotohno, Tomohiko Tamura, Akihide Ryo, Naoki Yamamoto
Publikováno v:
iScience, Vol 23, Iss 3, Pp-(2020)
iScience
iScience
Summary SynNotch receptor technology is a versatile tool that uses the regulatory notch core portion with an extracellular scFv and an intracellular transcription factor that enables to program customized input and output functions in mammalian cells
Publikováno v:
Heliyon, Vol 6, Iss 3, Pp e03598-(2020)
Heliyon
Heliyon
The pathophysiology of type 2 diabetes mellitus (T2DM) is characterized by not only insulin resistance, but also the abnormal regulation of glucagon secretion, suggesting that antagonizing the glucagon-induced signaling pathway has therapeutic potent