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Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 334-346 (2022)
Ferroptosis, a new form of non-apoptotic, regulated cell death characterized by iron dependency and lipid peroxidation, is involved in many pathological conditions such as neurodegenerative diseases, heart ischemia/reperfusion injury, acute renal fai
Autor:
Bingjian Wang, Xian Ji, Hui Wang, Qingguo Li, Zhe Lin, Haiping Fu, Ruigong Zhu, Jiajing Chen, Hongshan Chen, Xin Tang, Hong Jiang, Xuan Wu, Shixiu Sun, Xuesong Li
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 494-509 (2022)
Cellular senescence is closely associated with age-related diseases. Ovarian aging, a special type of organ senescence, is the pathophysiological foundation of the diseases of the reproductive system. It is characterized by the loss of integrity of t
Autor:
Tadaaki Sasaki, Yoshiki Ishigaki, Yohei Nakayama, Kanichi Seto, Saman Warnakulasuriya, Makoto Shiota, Keisuke Ohno, Shuji Hashimoto, Toru Nagao, Mitsuo Goto, Jinichi Fukuta, Kazuhito Satomura, Takashi Hanioka
Publikováno v:
International Dental Journal, Vol 72, Iss 1, Pp 123-132 (2022)
Objective The objective of this study was to assess the efficacy of a tobacco cessation intervention conducted by different dental specialists directed at a group of patients with tobacco-related oral diseases or undergoing implant treatment. Methods
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 394-405 (2022)
Biomimetic nanoengineering presents great potential in biomedical research by integrating cell membrane (CM) with functional nanoparticles. However, preparation of CM biomimetic nanomaterials for custom applications that can avoid the aggregation of
Autor:
Gui-qiong Huang, Zhang-Bin Tan, Hong-Mei Chen, Hui-Jie Fan, Ling-Peng Xie, Bin Liu, Yu-Ting Wu, Guanghong Chen, Ying-Chun Zhou, Min Liu, Hong-Lin Xu
Publikováno v:
Journal of Ginseng Research, Vol 46, Iss 1, Pp 156-166 (2022)
Journal of Ginseng Research
Journal of Ginseng Research
Background Panax ginseng Meyer (P. ginseng), a herb distributed in Korea, China and Japan, exerts benefits on diverse inflammatory conditions. However, the underlying mechanism and active ingredients remains largely unclear. Herein, we aimed to explo
Autor:
B. Holguin-Loya, G. Martinez-Mata, Uriel Soto-Barreras, Martina Nevárez-Rascón, Rubén Abraham Domínguez-Pérez, L. Sanin, R. Martinez–Martinez
Publikováno v:
Journal of Dental Sciences, Vol 17, Iss 1, Pp 211-216 (2022)
Background/purpose: The use of fluoride is known to reduce the risk of dental caries. There is limited information on the relationship between Streptococcus mutans (S. mutans) and fluoride exposure. This study investigated the association between the
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 80-94 (2022)
Genes & Diseases
Genes & Diseases
Infections caused by virus are one of the foremost causes of morbidity and mortality in the world. Although a number of antiviral drugs are currently used for treatment of various kinds of viral infection diseases, there is still no available therape
Autor:
Yun Dai, Zhuo Yu, Dandan Sun, Hao Yang, Liu Song, Shulan Han, Caitriona M. O'Driscoll, Jianfeng Guo, Di Chu, Jie Ma, Yifang Zou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 378-393 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The immune checkpoint blockade therapy has profoundly revolutionized the field of cancer immunotherapy. However, despite great promise for a variety of cancers, the efficacy of immune checkpoint inhibitors is still low in colorectal cancer (CRC). Thi
Autor:
Xiufu Lan, Jinzhi Wang, Zhaobo Cheng, Liu Yi, Qin Xiang, Hongbin Zhang, Yan Wang, Yun Xiao, Tingxiu Xiang, Li Chao, Jixiang Song, Ping Ju, Shu Zhang, Benxu Tan, Zheng Fu, Jian Zhang, Ke Xu, Lijuan Zhao
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 151-164 (2022)
Genes & Diseases
Genes & Diseases
This study aimed to investigate the relationships between LPCAT1 expression and clinicopathologic parameters of hepatocellular carcinoma (HCC), further, to explore the effect of LPCAT1 on overall survival (OS) in patients with HCC, and its possible m
Autor:
Toshiya Kamiyama, Yuji Morimoto, Yasunori Yagi, Kazuyuki Mizunoya, Akinobu Taketomi, Hirofumi Kamachi
Publikováno v:
HPB. 23(12):1897-1905
Background The timing of diagnosis of post-hepatectomy acute kidney injury (AKI) has rarely been investigated. The aim of this retrospective study was to reveal the differences between AKI subtypes following hepatectomy, as classified by timing of di