Zobrazeno 1 - 10
of 202
pro vyhledávání: ''
Autor:
Yun Dai, Zhuo Yu, Dandan Sun, Hao Yang, Liu Song, Shulan Han, Caitriona M. O'Driscoll, Jianfeng Guo, Di Chu, Jie Ma, Yifang Zou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 378-393 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The immune checkpoint blockade therapy has profoundly revolutionized the field of cancer immunotherapy. However, despite great promise for a variety of cancers, the efficacy of immune checkpoint inhibitors is still low in colorectal cancer (CRC). Thi
Autor:
Toshiaki Kume, Yasuhiko Izumi, Yuki Takada-Takatori, Masahito Sawahata, Mami Matsumoto, Moeri Miyamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 147, Iss 1, Pp 138-142 (2021)
We previously generated an ischemic stroke in a zebrafish model using N2 gas perfusion; however, this model was an unsuitable drug screening system due to low throughput. In this study, we examined a zebrafish ischemic stroke model using an oxygen ab
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 938-961 (2021)
Toxicology Reports, Vol 8, Iss, Pp 938-961 (2021)
Graphical abstract
Highlights • Flavor enhancing high lipid diet acts as silent killer. • Monosodium glutamate mixed with high lipid diet alters redox-status. • Monosodium glutamate mixed with high lipid diet induces systemic anomalies.
Highlights • Flavor enhancing high lipid diet acts as silent killer. • Monosodium glutamate mixed with high lipid diet alters redox-status. • Monosodium glutamate mixed with high lipid diet induces systemic anomalies.
Autor:
Tahereh Poordast, Zohreh Mostafavi-Pour, Fatemeh Zal, Maryam Kasraeian, Navid Jamali, Negar Nejabat
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 60, Iss 2, Pp 216-220 (2021)
Objective Considering the role of oxidative stress in the development and progression of endometriosis, the ameliorative effect of caffeic acid treatment on ectopic, eutopic endometrial cells enzyme activities was investigated. We also determined the
Publikováno v:
Poultry Science, Vol 100, Iss 1, Pp 73-83 (2021)
Poultry Science
Poultry Science
The aim of this study was to investigate the effects of osteocalcin (OCN) on fatty liver hemorrhagic syndrome (FLHS) in aged laying hens. Thirty 68-week-old White Plymouth laying hens were randomly assigned into conventional single-bird cages, and th
Publikováno v:
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 1001-1009 (2021)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Bromelain is a proteolytic mixture obtained from pineapple (Ananas comosus (L. Merr)). It has diversified clinical properties and is used in alleviation of cancer, inflammation and oxidative stress. The current study focuses on extraction of bromelai
Autor:
Reham I. Alagal, Lujain Abdulaziz Almousa, Dalal H. Aljabryn, Jozaa Zaidan ALTamimi, Ghedeir M. Alshammari, Mohammed A. Yahya, Nora Abdullah AlFaris, Nora M. AlKehayez
Publikováno v:
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 170-182 (2021)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
This study examined the impact of different cooking methods on fatty acid (FAs) composition of shrimp meat and the ability of these foods to protect against high cholesterol (HC) diet-induced non-alcoholic fatty liver disease (NAFLD) in rats. Shrimp
Autor:
William R. Jacobs, Maria A. Pasillas, Ailidh Burgess, Tom L. Blundell, Sangeeta Tiwari, Anthony G. Coyne, James Cory-Wright, Vitor Mendes, Clio Meghir, Víctor Sebastián-Pérez, Sherine E. Thomas, Shaymaa A. Zaidan, Emma Cattermole, Pooja Gupta, Chris Abell
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3491-3506 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Computational and Structural Biotechnology Journal
'Computational and Structural Biotechnology Journal ', vol: 19, pages: 3491-3506 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Computational and Structural Biotechnology Journal
'Computational and Structural Biotechnology Journal ', vol: 19, pages: 3491-3506 (2021)
16 p.-8 fig.-4 tab.
The L-arginine biosynthesis pathway consists of eight enzymes that catalyse the conversion of L-glutamate to L-arginine. Arginine auxotrophs (argB/argF deletion mutants) of Mycobacterium tuberculosis are rapidly sterilised in
The L-arginine biosynthesis pathway consists of eight enzymes that catalyse the conversion of L-glutamate to L-arginine. Arginine auxotrophs (argB/argF deletion mutants) of Mycobacterium tuberculosis are rapidly sterilised in
Evaluation of metabolic, antioxidant and anti-inflammatory effects of Garcinia kola on diabetic rats
Autor:
Paul F. Seke Etet, Ahmed El Tahir Idris, Shuaa Z. AlShammari, Mohammed Farahna, Muaawia A. Hamza, Abdalla A. Saeed, Gwiria M. H. Satti
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 12, Pp 3641-3646 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Garcinia kola (G. kola), is a plant characterized by its hypoglycemic properties. We recently reported our findings on the extracts of G. kola, in which we found that it prevented the loss of inflammation-sensible neuronal populations in streptozotoc
Publikováno v:
Annals of Medicine and Surgery
Metabolism is a tightly regulated sequence of events, supported by key reactions between enzymes and enzyme-specific substrates. These reactions have the potential to produce metabolic side products that can have deleterious effects to further key me