Zobrazeno 1 - 10
of 232
pro vyhledávání: ''
Autor:
Arnaud Droit, Elvira Mass, Corey A. Scipione, Raphaëlle Bourgeois, Benoit J. Arsenault, Philippe Pibarot, Patrick Mathieu, Sylvie Bourassa, Audrey-Anne Després, Arnaud Girard, Marlys L. Koschinsky, Paolo Poggio, Jakie Guertin, Patricia L. Mitchell, Michael B. Boffa, Christian Couture, Patrick Couture, Romain Capoulade, Sébastien Thériault, Clarisse Gotti, Nicolas Perrot
Publikováno v:
CJC Open, Vol 3, Iss 4, Pp 450-459 (2021)
CJC Open
CJC Open
Background: Lipoprotein(a) (Lp[a]), which consists of a low-density lipoprotein (LDL) bound to apolipoprotein(a), is one of the strongest genetic risk factors for atherosclerotic cardiovascular diseases. Few studies have performed hypothesis-free dir
Autor:
Zhi-Hui He, Shu-Wen Qian, Qi Qun Tang, Ying Zou, Liang Guo, Yi-Na Wang, Meng Ding, Hong Ma, Yan Tang, Yang Liu
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1589-1604 (2020)
Journal of Lipid Research
Journal of Lipid Research
Beiging of white adipose tissue (WAT) has beneficial effects on metabolism. Although it is known that beige adipocytes are active in lipid catabolism and thermogenesis, how they are regulated deserves more explorations. In this study, we demonstrate
Autor:
Anne Laure Rerole, Alain Carrié, Samir Saheb, David Masson, Wilfried Le Goff, Isabelle Fournel, Randa Bittar, Hélène Choubley, Thomas Gautier, Jean-Pierre Quenot, Jean-Paul Pais de Barros, Auguste Dargent, Laurent Lagrost
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1776-1783 (2020)
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
International audience; Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient to improve outcome during septic shock. An extracorporeal removal
Autor:
Graeme I. Lancaster, Denis Sviridov, Nigora Mukhamedova, Takahiro Kameda, Gerard Pernes, Peter J. Meikle, Ryunosuke Ohkawa, Boris L. Vaisman, Andrew J. Murphy, Ayuko Hara, Ying Fu, Michael Ditiatkovski, Shao-Jui Lai, Paul J. Nestel, Alan T. Remaley, Hann Low, Dmitri Sviridov, Minoru Tozuka, Yuna Horiuchi, Mai Sasaoka, Azusa Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
J Lipid Res
J Lipid Res
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort
Autor:
Tiziano Lucchi, Tiziana Sampietro, Giuliano Boscutti, Fabrizio Veglia, Alice Ossoli, Loreto Gesualdo, Marcello Arca, Laura Calabresi, Laura D'Erasmo, Chiara Pavanello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1784-1788 (2020)
J Lipid Res
J Lipid Res
Familial LCAT deficiency (FLD) is a rare genetic disorder of HDL metabolism, caused by loss-of-function mutations in the LCAT gene and characterized by a variety of symptoms including corneal opacities and kidney failure. Renal disease represents the
Autor:
Mouna Taroua, Christiane Auray-Blais, Siamak Jabbarzadeh-Tabrizi, Raphael Schiffmann, Jin-Song Shen, Taniqua S. Day, Michel Boutin
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1410-1423 (2020)
J Lipid Res
J Lipid Res
Fabry disease is caused by deficient activity of α-galactosidase A, an enzyme that hydrolyzes the terminal α-galactosyl moieties from glycolipids and glycoproteins, and subsequent accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb
Autor:
Benjamin M. Abraham, Felix Zhou, Edward A. Fisher, Johannes von Lintig, Ivan Pinos, Jaume Amengual, Tessa J. Barrett, Xiaoyun Wu
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1491-1503 (2020)
J Lipid Res
J Lipid Res
Atherosclerosis is characterized by the pathological accumulation of cholesterol-laden macrophages in the arterial wall. Atherosclerosis is also the main underlying cause of CVDs, and its development is largely driven by elevated plasma cholesterol.
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1504-1511 (2020)
J Lipid Res
J Lipid Res
Accompanied with nutrition transition, non-HDL-C levels of individuals in Asian countries has increased rapidly, which has caused the global epicenter of nonoptimal cholesterol to shift from Western countries to Asian countries. Thus, it is critical
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1437-1449 (2020)
Among the virulence factors in Neisseria infections, a major inducer of inflammatory cytokines is the lipooligosaccharide (LOS). The activation of NF-κB via extracellular binding of LOS or lipopolysaccharide (LPS) to the toll-like receptor 4 and its
Autor:
Patrick Roddy, L. Ashley Cowart, David J. Montefusco, Johana M. Lambert, William L. Holland, Andrea K. Anderson, Bao Ngan Tran
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 10, Pp 1328-1340 (2020)
J Lipid Res
J Lipid Res
Sphingolipids have become established participants in the pathogenesis of obesity and its associated maladies. Sphingosine kinase 1 (SPHK1), which generates S1P, has been shown to increase in liver and adipose of obese humans and mice and to regulate