Zobrazeno 241 - 250
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pro vyhledávání: ''
Autor:
Kyle S. McCommis, Erica R. Gansemer, Abdul Qaadir King-McAlpin, Eric B. Taylor, Michael R. Martino, Brian N. Finck, Matthew J. Potthoff, D. Thomas Rutkowski
Publikováno v:
iScience, Vol 23, Iss 5, Pp-(2020)
iScience
iScience
Summary Many metabolic diseases disrupt endoplasmic reticulum (ER) homeostasis, but little is known about how metabolic activity is communicated to the ER. Here, we show in hepatocytes and other metabolically active cells that decreasing the availabi
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
New insights about nanomaterials' biodistribution revealed their ability to achieve tumor accumulation by taking advantage from the dynamic vents occurring in tumor's vasculature. This paradigm-shift emphasizes the importance of extending nanomateria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c59a4e54a1818ac1afd656fcc8c7d3d
Autor:
Qonita Kurnia Anjani, Ryan F. Donnelly, Eneko Larrañeta, Álvaro Cárcamo-Martínez, Andi Dian Permana, Ana Sara Cordeiro
Publikováno v:
International Journal of Pharmaceutics: X
International Journal of Pharmaceutics: X, Vol 2, Iss, Pp 100048-(2020)
Cárcamo-Martínez, Á, Anjani, Q K, Permana, A D, Cordeiro, A S, Larrañeta, E & Donnelly, R F 2020, ' Coated polymeric needles for rapid and deep intradermal delivery ', International Journal of Pharmaceutics: X, vol. 2, 100048 . https://doi.org/10.1016/j.ijpx.2020.100048
International Journal of Pharmaceutics: X, Vol 2, Iss, Pp 100048-(2020)
Cárcamo-Martínez, Á, Anjani, Q K, Permana, A D, Cordeiro, A S, Larrañeta, E & Donnelly, R F 2020, ' Coated polymeric needles for rapid and deep intradermal delivery ', International Journal of Pharmaceutics: X, vol. 2, 100048 . https://doi.org/10.1016/j.ijpx.2020.100048
Two groups of single polymeric needles (crosslinked Gantrez®S-97 and poly(ethylene glycol)) of different lengths (2 mm and 4.5 mm) with defined base widths were fabricated and tested in terms of their mechanical strength and insertion abilities usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61201951797644d04f24b76bc94f5be
https://doi.org/10.1016/j.ijpx.2020.100048
https://doi.org/10.1016/j.ijpx.2020.100048
Publikováno v:
iScience, Vol 23, Iss 4, Pp-(2020)
iScience
iScience
Summary The neural retina and retinal pigment epithelium (RPE) maintain a symbiotic metabolic relationship, disruption of which leads to debilitating vision loss. The current study was undertaken to identify the differences in the steady-state metabo
Non Destructive Testing (NDT) by active InfraRed Thermography (IRT) of bonded Carbon Fibers Reinforced Plastic (CFRP) laminates is a very challenging issue. Adding Boron Nitride (BN) particles within the joint material provides an interesting solutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd15ea34aaa0318e49a5406255dbabe7
https://oatao.univ-toulouse.fr/26994/
https://oatao.univ-toulouse.fr/26994/
Autor:
Hiroyuki Sasanuma, Remi Akagawa, Shunichi Takeda, Masato T. Kanemaki, Masataka Tsuda, Shintaro Yamada, Hai Thanh Trinh, Liton Kumar Saha, Kouji Hirota, Atsushi Shibata, Shinichiro Nakada
Publikováno v:
iScience, Vol 23, Iss 4, Pp-(2020)
iScience
iScience
Summary Chemical modifications and adducts at DNA double-strand break (DSB) ends must be cleaned before re-joining by non-homologous end-joining (NHEJ). MRE11 nuclease is essential for efficient removal of Topoisomerase II (TOP2)-DNA adducts from TOP
Iron-Catalyzed Asymmetric Hydrosilylation of Vinylcyclopropanes via Stereospecific C-C Bond Cleavage
Autor:
Yang Shi, Hongliang Wang, Yufeng Sun, Jiayan Cui, Shijia Yu, Xin Hong, Chenhui Chen, Jianbo Xie, Zhan Lu
Publikováno v:
iScience, Vol 23, Iss 4, Pp-(2020)
iScience
iScience
Summary An iron-catalyzed highly anti-Markovnikov selective, enantioselective hydrosilylation of vinylcyclopropanes with PhSiH3 was reported for the preparation of valuable chiral allylic silanes via stereospecific C-C bond cleavage. Simultaneously,
Publikováno v:
iScience, Vol 23, Iss 4, Pp-(2020)
iScience
iScience
Summary Protons are highly related to cell viability during physiological and pathological processes. Developing new probes to monitor the pH variation could be extremely helpful to understand the viability of cells and the cell death study. Carboniz
Autor:
G. Kate Park, Kai Bao, Thomas E. Clancy, Jeong Heon Lee, Myunghwan Choi, Seok Hyun Yun, Eduardo Soriano, Do-Yeon Kim, Maged Henary, John V. Frangioni, Wataru Katagiri, Jihye Paik, Satoshi Kashiwagi, Hak Soo Choi
Publikováno v:
iScience, Vol 23, Iss 4, Pp-(2020)
iScience
iScience
Summary Design of tissue-specific contrast agents to delineate tumors from background tissues is a major unmet clinical need for ultimate surgical interventions. Bioconjugation of fluorophore(s) to a ligand has been mainly used to target overexpresse
Publikováno v:
iScience
iScience, Vol 23, Iss 4, Pp-(2020)
iScience, Vol 23, Iss 4, Pp-(2020)
Summary Carbon-carbon bond formation through polarity reversal ketyl radical anion coupling of carbonyls has inspired new reaction modes to this cornerstone carbonyl group and played significant roles in organic chemistry. The introduction of this re