Zobrazeno 51 - 60
of 609
pro vyhledávání: ''
Autor:
Andrew S. Herbert, Jawed Fareed, John M. Dye, Samantha E. Zak, Dawid Maciorowski, Yash Gupta, Prakasha Kempaiah, Chandrashekhar Vishwanath Kulkarni, Ravi Durvasula
Publikováno v:
International Journal of Biological Macromolecules
The world is currently facing a novel coronavirus (SARS-CoV-2) pandemic. The greatest threat that is disrupting the normal functioning of society is the exceptionally high species independent transmission. Drug repurposing is understood to be the bes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea065f947773bf8e5c62267b4dd2916
Autor:
André Moreni Lopes, Angela Faustino Jozala, Luís Abrunhosa, Isabelle S. Kurnik, Louise Lacalendola Tundisi, Thais Francine Ribeiro Alves, Mariana A. Noronha, Joana Martins, Laura de Oliveira Nascimento, António A. Vicente, Natália A. D'Angelo, Mayra C.C. Câmara, Priscila Gava Mazzola, Juliana Souza Ribeiro Costa, Jorge M. Vieira, Janaína Artem Ataide, Marco Vinícius Chaud
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal pre-proofs
Curcumin (CUR) is a phenolic compound present in some herbs, including Curcuma longa Linn. (turmeric rhizome), with a high bioactive capacity and characteristic yellow color. It is mainly used as a spice, although it has been
Curcumin (CUR) is a phenolic compound present in some herbs, including Curcuma longa Linn. (turmeric rhizome), with a high bioactive capacity and characteristic yellow color. It is mainly used as a spice, although it has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c797eab0e5542b8c24b77c74870b2228
Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation
Autor:
Joel Fauser, Christian Hedberg, Aymelt Itzen, Dorothea Höpfner, Marietta S. Kaspers, Christian Pett
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102731-(2021)
iScience
iScience, Vol 23, Iss 12, Pp 101800-(2020)
iScience
iScience, Vol 23, Iss 12, Pp 101800-(2020)
Summary AMPylation is a post-translational modification that modifies amino acid side chains with adenosine monophosphate (AMP). Recently, a role of AMPylation as a universal regulatory mechanism in infection and cellular homeostasis has emerged, dri
Autor:
Berry Pinshow, Susan W. Nicolson, Jorge E. Schondube, Jonathan A. Rader, Carlos Martínez del Rio, Patricia A. Fleming, Todd J. McWhorter, Yocelyn T. Gutiérrez-Guerrero
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102717-(2021)
iScience
iScience
Summary The major lineages of nectar-feeding birds (hummingbirds, sunbirds, honeyeaters, flowerpiercers, and lorikeets) are considered examples of convergent evolution. We compared sucrose digestion capacity and sucrase enzymatic activity per unit in
Autor:
Nuno M. Neves, Catarina Oliveira, Rui L. Reis, Tiago H. Silva, Simone S. Silva, L. L. Reys, Albino Martins
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Implantation of biomaterials and hybrid constructs in tissue engineering approaches presents major limitations such as inflammatory reaction and the lack of vasculature integration. Therefore, new strategies are needed to enhance implant function, im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333734e780e190b6ec7717b22db5e690
Autor:
Henk-Jan Guchelaar, H.C.M. Bijleveld-Olierook, N. Ouwerkerk, W.M. Zaal, D.M. Kweekel, J.J.D. van Uitert, P.P.H. Le Brun, A.D. van Unen, J.M. Tichem, I. Lafeber, Kirsten J. M. Schimmel
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, 603. ELSEVIER
International Journal of Pharmaceutics, 603. ELSEVIER
Three-dimensional (3D) printing of pharmaceuticals has the potential to revolutionise personalised medicine but is as yet largely unexplored. A proof-of-concept study of a novel heated, piston-driven semi-solid extrusion 3D printer was performed by p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8484cd1ff12e16ebd44d74595d7e027
https://hdl.handle.net/1887/3196262
https://hdl.handle.net/1887/3196262
Autor:
Luke H. Rhym, Balkrishen Bhat, Umberto Capasso Palmiero, Asha K. Patel, Daniel G. Anderson, James C. Kaczmarek, Frank Derosa, Michael W. Heartlein
Non-viral vectors offer the potential to deliver nucleic acids including mRNA and DNA into cells in vivo. However, designing materials that effectively deliver to target organs and then to desired compartments within the cell remains a challenge. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aa9b58bdd4a90ca6af0d388ca1368f
http://hdl.handle.net/10044/1/90329
http://hdl.handle.net/10044/1/90329
For decades, naturally produced plants have been studied and used in herbalism (herbal medicines). Despite being natural, these products were not of any interest of any of the major pharmaceutical companies. There are various reasons behind this igno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d496bfe3ba4657995d63e300e2cf64e4
http://sure.sunderland.ac.uk/id/eprint/13248/1/13248.pdf
http://sure.sunderland.ac.uk/id/eprint/13248/1/13248.pdf
Autor:
Himjyot Jaiswal, Philip J. Starkey Lewis, Carl S. Tucker, James W. Dear, Joanna Simpson, Jeremy Hughes, Oliver Flint, Sofia Ferreira-Gonzalez, Baltasar Lucendo-Villarin, Natalie Z.M. Homer, Esther Mellado-Gomez, Stuart J. Forbes, Enrique M. Toledo, Allan E. Karlsen, Nicola L. Beer, Jose Meseguer-Ripolles, David C. Hay, Yu Wang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102552-(2021)
iScience
Meseguer Ripolles, J, Lucendo Villarin, B, Tucker, C, Ferreira-Gonzalez, S, Homer, N Z M, Wang, Y, Starkey Lewis, P, Toledo Maldonado, E, Mellado-Gomez, E, Simpson, J, Flint, O, Jaiswal, H, Beer, N L, Karlsen, A E, Forbes, S J, Dear, J W, Hughes, J & Hay, D C 2021, ' Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure ', iScience . https://doi.org/10.1016/j.isci.2021.102552
iScience
Meseguer Ripolles, J, Lucendo Villarin, B, Tucker, C, Ferreira-Gonzalez, S, Homer, N Z M, Wang, Y, Starkey Lewis, P, Toledo Maldonado, E, Mellado-Gomez, E, Simpson, J, Flint, O, Jaiswal, H, Beer, N L, Karlsen, A E, Forbes, S J, Dear, J W, Hughes, J & Hay, D C 2021, ' Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure ', iScience . https://doi.org/10.1016/j.isci.2021.102552
Summary Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response and are used clinically to treat disease. In t
Autor:
Chong Shen, Zehai Xu, Guoliang Zhang, Yufan Zhang, Qin Meng, Yinghua Lu, Xu Zhang, Yujie Zhu, Congjie Gao
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102576-(2021)
iScience
iScience
Summary Graphene oxide (GO) nanosheets with unique structure have received much attention in providing opportunity for high-performance membranes in separation. However, the rational design of ultrathin graphene membranes with controlled structures r