Zobrazeno 1 - 10
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pro vyhledávání: ''
Autor:
Amit Meller, Maisa Nasser
Publikováno v:
iScience
iScience, Vol 25, Iss 1, Pp 103554-(2022)
iScience, Vol 25, Iss 1, Pp 103554-(2022)
Summary Single biomolecule sensing often requires the quantification of multiple fluorescent species. Here, we theoretically and experimentally use time-resolved fluorescence via Time Correlated Single Photon Counting (TCSPC) to accurately quantify f
Publikováno v:
International Journal of Biological Macromolecules
Vora, L K, Courtenay, A J, Tekko, I A, Larrañeta, E & Donnelly, R F 2020, ' Pullulan-based dissolving microneedle arrays for enhanced transdermal delivery of small and large biomolecules ', International Journal of Biological Macromolecules, vol. 146, pp. 290-298 . https://doi.org/10.1016/j.ijbiomac.2019.12.184
Vora, L K, Courtenay, A J, Tekko, I A, Larrañeta, E & Donnelly, R F 2020, ' Pullulan-based dissolving microneedle arrays for enhanced transdermal delivery of small and large biomolecules ', International Journal of Biological Macromolecules, vol. 146, pp. 290-298 . https://doi.org/10.1016/j.ijbiomac.2019.12.184
One specific technological advance in transdermal drug delivery is the development of dissolving microneedles (DMNs), which efficiently deliver therapeutics through a rapid dissolution of polymers after penetration into the skin. However, there is a
Autor:
Andreas Ebneth, Luke A. Miles, S.J. Hermans, Marie-Laure Rives, Daniel Oehlrich, Berthold Wroblowski, Jasmina Markulić, Michael W. Parker, Ines Royaux, Nancy C. Hancock, Gabriela A. N. Crespi, Andrés A. Trabanco, Jonathan H. Gooi, Larissa Doughty, Tracy L. Nero
Publikováno v:
iScience, Vol 19, Iss, Pp 110-118 (2019)
iScience
iScience
Summary Polymorphism in the microglial receptor CD33 gene has been linked to late-onset Alzheimer disease (AD), and reduced expression of the CD33 sialic acid-binding domain confers protection. Thus, CD33 inhibition might be an effective therapy agai
Autor:
Teresita Bellido, Alexander G. Robling, April M. Hoggatt, Andrew J. Elmendorf, Daniel J. Horan, Amy Y. Sato, Fredrick M. Pavalko, Gabriela G. Loots, Whitney A. Bullock
Publikováno v:
iScience
iScience, Vol 20, Iss, Pp 205-215 (2019)
iScience, Vol 20, Iss, Pp 205-215 (2019)
Summary Wnt signaling plays a key role in regulating bone remodeling. In vitro studies suggest that sclerostin's inhibitory action on Lrp5 is facilitated by the membrane-associated receptor Lrp4. We generated an Lrp4 R1170W knockin mouse model (Lrp4K
Autor:
Young Moo Choo, Nannan Liu, Fangfang Zeng, Anthony J. Cornel, Kaiming Tan, Tsung-Yu Chen, Walter S. Leal, Pingxi Xu, Zhou Chen
Publikováno v:
iScience, Vol 19, Iss, Pp 25-38 (2019)
iScience
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
iScience
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Summary How chemical signals are integrated at the peripheral sensory system of insects is still an enigma. Here we show that when coexpressed with Orco in Xenopus oocytes, an odorant receptor from the southern house mosquito, CquiOR32, generated inw
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103237-(2021)
iScience, 24(11)
iScience, Vol 24, Iss 11, Pp 103237-(2021)
iScience, 24(11)
Summary We have developed a fabrication methodology for label-free optical trapping of individual nanobeads and proteins in inverted-bowtie-shaped plasmonic gold nanopores. Arrays of these nanoapertures can be reliably produced using focused ion beam
Autor:
José A. Teixeira, João Carlos Sousa, Marisa P. Sárria, Andreia C. Gomes, Ivo Lopes, Luana Magalhães, Raul Machado, Cláudia Botelho, Mário Marques Fernandes
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Exosomes are cell-derived vesicles that act as carriers for proteins and nucleic acids, with therapeutic potential and high biocompatibility. We propose a new concept of exosome-like liposomes for controlled delivery. The goal of this work was to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456b30909c84330656214cfa93b408c7
Xyloglucan and Concanavalin A based dressings in the topical treatment of mice wound healing process
Autor:
Maria G. Carneiro-da-Cunha, Túlio Diego da Silva, Márcia Vanusa da Silva, Marthyna P. Souza, António A. Vicente, Maria Tereza dos Santos Correia, Priscilla Barbosa Sales de Albuquerque, Paulo A.G. Soares, Paloma Lys de Medeiros, Isabel R.S. Arruda
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Carbohydrate Polymer Technologies and Applications, Vol 2, Iss, Pp 100136-(2021)
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Carbohydrate Polymer Technologies and Applications, Vol 2, Iss, Pp 100136-(2021)
For medical biomaterials, xyloglucan dispersions can form films or gels to be applied as a wound dressing. For this purpose, the structural characterization of xyloglucan dressing (XG) and xyloglucan dressing containing 0.5 mg/mL of concanavalin A (X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46af923596e67984f36cbe1c927a0f6
Autor:
André Moreni Lopes, Angela Faustino Jozala, Luís Abrunhosa, Isabelle S. Kurnik, Louise Lacalendola Tundisi, Thais Francine Ribeiro Alves, Mariana A. Noronha, Joana Martins, Laura de Oliveira Nascimento, António A. Vicente, Natália A. D'Angelo, Mayra C.C. Câmara, Priscila Gava Mazzola, Juliana Souza Ribeiro Costa, Jorge M. Vieira, Janaína Artem Ataide, Marco Vinícius Chaud
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal pre-proofs
Curcumin (CUR) is a phenolic compound present in some herbs, including Curcuma longa Linn. (turmeric rhizome), with a high bioactive capacity and characteristic yellow color. It is mainly used as a spice, although it has been
Curcumin (CUR) is a phenolic compound present in some herbs, including Curcuma longa Linn. (turmeric rhizome), with a high bioactive capacity and characteristic yellow color. It is mainly used as a spice, although it has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c797eab0e5542b8c24b77c74870b2228
Autor:
Marco De Zuani, Francesca Cavalieri, Shyam Sushama Jose, Jan Fric, Giancarlo Forte, Lukáš Kubala, Kamila Bendíčková, Frank Caruso, Federico Tidu
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102683-(2021)
iScience
iScience
Summary Mesenchymal stromal cells (MSCs) combined with calcineurin-nuclear factor of activated T cell (CN-NFAT) inhibitors are being tested as a treatment for graft-versus-host disease (GvHD). The immunosuppressive properties of MSCs seem beneficial;