Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Catherine L. Drennan"'
Autor:
Jana Narasimhan, Suzanne Letinski, Stephen P Jung, Aleksey Gerasyuto, Jiashi Wang, Michael Arnold, Guangming Chen, Jean Hedrick, Melissa Dumble, Kanchana Ravichandran, Talya Levitz, Chang Cui, Catherine L Drennan, JoAnne Stubbe, Gary Karp, Arthur Branstrom
Publikováno v:
eLife. 11
Antibiotic-resistant Neisseria gonorrhoeae (Ng) are an emerging public health threat due to increasing numbers of multidrug resistant (MDR) organisms. We identified two novel orally active inhibitors, PTC-847 and PTC-672, that exhibit a narrow spectr
Autor:
Jana Narasimhan, Suzanne Letinski, Stephen P Jung, Aleksey Gerasyuto, Jiashi Wang, Michael Arnold, Guangming Chen, Jean Hedrick, Melissa Dumble, Kanchana Ravichandran, Talya Levitz, Chang Cui, Catherine L Drennan, JoAnne Stubbe, Gary Karp, Arthur Branstrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242c3ecb2516113bcfac9a95f12d9626
https://doi.org/10.7554/elife.67447.sa2
https://doi.org/10.7554/elife.67447.sa2
Autor:
Emily P. Balskus, Ronald T. Raines, Mary C. Andorfer, Catherine L. Drennan, Lindsey R. F. Backman, Yolanda Y. Huang, Brian Gold
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The glycyl radical enzyme (GRE) superfamily utilizes a glycyl radical cofactor to catalyze difficult chemical reactions in a variety of anaerobic microbial metabolic pathways. Recently, a GRE, trans-4-hydroxy-L-proline (Hyp) dehydratase (HypD), was d
Autor:
Christophe Léger, Mériem Merrouch, Chie Ueda, Catherine L. Drennan, Vincent Fourmond, Sébastien Dementin, Laura Fradale, Elizabeth C. Wittenborn, Maria-Eirini Pandelia
Publikováno v:
eLife
eLife, 2018, 7, ⟨10.7554/eLife.39451⟩
eLife, Vol 7 (2018)
eLife, eLife Sciences Publication, 2018, 7, ⟨10.7554/eLife.39451⟩
eLife, 2018, 7, ⟨10.7554/eLife.39451⟩
eLife, Vol 7 (2018)
eLife, eLife Sciences Publication, 2018, 7, ⟨10.7554/eLife.39451⟩
The C-cluster of the enzyme carbon monoxide dehydrogenase (CODH) is a structurally distinctive Ni-Fe-S cluster employed to catalyze the reduction of CO2 to CO as part of the Wood-Ljungdahl carbon fixation pathway. Using X-ray crystallography, we have
Autor:
Mériem Merrouch, Christophe Léger, Elizabeth C. Wittenborn, Vincent Fourmond, Catherine L. Drennan, Chie Ueda, Maria-Eirini Pandelia, Laura Fradale, Sébastien Dementin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa89b63c478feda21747bb8d9e7461a
https://doi.org/10.7554/elife.39451.031
https://doi.org/10.7554/elife.39451.031
Autor:
Edward J Brignole, Kuang-Lei Tsai, Johnathan Chittuluru, Haoran Li, Yimon Aye, Pawel A Penczek, JoAnne Stubbe, Catherine L Drennan, Francisco Asturias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f663efe24bc4e09b19fd94ea2b3f1fc
https://doi.org/10.7554/elife.31502.023
https://doi.org/10.7554/elife.31502.023
Publikováno v:
eLife, Vol 5 (2016)
eLife Sciences Publications, Ltd.
eLife Sciences Publications, Ltd.
The metallocofactor involved in fixing nitrogen is not a rigid scaffold, as was previously thought.
Autor:
Michael A. Funk, Christina M Zimanyi, Catherine L. Drennan, Percival Yang-Ting Chen, Gyunghoon Kang
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife Sciences Publications, Ltd.
eLife, Vol 5 (2016)
eLife Sciences Publications, Ltd.
Ribonucleotide reductase (RNR) converts ribonucleotides to deoxyribonucleotides, a reaction that is essential for DNA biosynthesis and repair. This enzyme is responsible for reducing all four ribonucleotide substrates, with specificity regulated by t