Zobrazeno 1 - 1
of 1
pro vyhledávání: '"David L. Huso"'
A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome
Autor:
Hamid Ehsan, Mark J. Caulfield, Oliver Squires, Nick Huso, Djahida Bedja, Nicole K Wilson, Jefferson J. Doyle, Jennifer P Habashi, Florian Schoenhoff, Mark E. Lindsay, David L. Huso, Benjamin Rusholme, Craig J. Thomas, Suha Bachir, Daniel P. Judge, Alexander J Doyle, Loretha Myers, Ryan Whitworth, Harry C. Dietz, Jennifer E. Van Eyk
Publikováno v:
eLife
eLife, Vol 4 (2015)
Elife, 4
Doyle, Jefferson J; Doyle, Alexander J; Wilson, Nicole K; Habashi, Jennifer P; Bedja, Djahida; Whitworth, Ryan E; Lindsay, Mark E; Schönhoff, Florian; Myers, Loretha; Huso, Nick; Bachir, Suha; Squires, Oliver; Rusholme, Benjamin; Ehsan, Hamid; Huso, David; Thomas, Craig J; Caulfield, Mark J; Van Eyk, Jennifer E; Judge, Daniel P and Dietz, Harry C (2015). A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome. eLife, 4 eLife Sciences Publications 10.7554/eLife.08648
eLife, Vol 4 (2015)
Elife, 4
Doyle, Jefferson J; Doyle, Alexander J; Wilson, Nicole K; Habashi, Jennifer P; Bedja, Djahida; Whitworth, Ryan E; Lindsay, Mark E; Schönhoff, Florian; Myers, Loretha; Huso, Nick; Bachir, Suha; Squires, Oliver; Rusholme, Benjamin; Ehsan, Hamid; Huso, David; Thomas, Craig J; Caulfield, Mark J; Van Eyk, Jennifer E; Judge, Daniel P and Dietz, Harry C (2015). A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome. eLife, 4 eLife Sciences Publications 10.7554/eLife.08648
Calcium channel blockers (CCBs) are prescribed to patients with Marfan syndrome for prophylaxis against aortic aneurysm progression, despite limited evidence for their efficacy and safety in the disorder. Unexpectedly, Marfan mice treated with CCBs s