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Publikováno v:
Molecular Medicine Reports
The prognosis of advanced non‑small cell lung cancer (NSCLC) is poor; therefore, identifying novel treatment strategies for patients with NSCLC is important. The present study aimed to investigate the efficacy of apatinib plus docetaxel vs. docetax
Publikováno v:
Oncology Letters
Cordycepin is an extract from the Cordyceps genus of ascomycete fungi. In the present study, the anticancer potential of cordycepin against nasopharyngeal carcinoma (NPC), and the potential underlying mechanisms, were investigated. Using Cell Countin
Publikováno v:
Molecular Medicine Reports
Blunt chest trauma with hemorrhagic shock frequently induces pulmonary inflammation that leads to acute lung injury (ALI). The present study aimed to explore the protective effects of dexmedetomidine (Dex) in blunt chest trauma and hemorrhagic shock
Publikováno v:
Molecular Medicine Reports
It has been reported that mannose exerts antitumour effects against certain types of cancer. The present study was designed to evaluate whether mannose exerted potential anticancer effects on A549 and H1299 non‑small cell lung cancer (NSCLC) cells
Autor:
Takuya Iwama, Mikihiro Fujiya, Takuma Goto, Akemi Kita, Naoki Ogawa, Shuhei Takauji, Masami Ijiri, Toshikatsu Okumura, Katsuyoshi Ando, Hiroki Tanaka, Aki Sakatani, Shin Kashima, Yuki Murakami, Hiroaki Konishi, Nobuhiro Ueno
Publikováno v:
International Journal of Oncology
Pancreatic cancer is associated with a poor prognosis due to challenges in early detection, severe progression of the primary tumor, metastatic lesions, and resistance to antitumor agents. However, previous studies have indicated a relationship betwe
Autor:
Chi-Tung Cheng, Ta Sen Yeh, Chun‑Yi Tsai, Shang-Yu Wang, Chun Nan Yeh, Jen-Shi Chen, Chia‑Hsiang Hu
Publikováno v:
Oncology Letters
The present study aimed to conduct a prognosis analysis of Taiwanese patients with metastatic gastrointestinal stromal tumors (GISTs), who are resistant to or were unable to tolerate imatinib or sunitinib, and were subsequently treated with regorafen
Autor:
Danielle S. Bitterman, Miranda B. Lam, Nayan Lamba, Sana Raoof, Daniel Kim, Amandeep R. Mahal, Grace M. Lee, Nina N. Sanford, Harvey J. Mamon
Publikováno v:
Molecular and Clinical Oncology
There are few treatment guidelines for locally recurrent esophageal cancer after trimodality treatment (pre-operative chemoradiation followed by surgery) in patients with a poor performance status. The purpose of this single institutional, retrospect
Publikováno v:
Molecular Medicine Reports
Bisphenol A (BPA), a xenoestrogen commonly used in plastics, may act as an endocrine disruptor, which indicates that BPA might be a public health risk. The present study aimed to investigate the effect of BPA on 17β‑estradiol (E2)‑mediated prote
Publikováno v:
Oncology Letters
Dasatinib, a multikinase inhibitor, is used in the treatment of chronic myeloid leukemia and was developed to overcome imatinib resistance. Its mechanism of action involves the induction of apoptosis, autophagy and necroptosis. However, it remains un
Publikováno v:
Oncology Reports
Chemo‑photothermal therapy for cancer treatment has received increasing attention due to its selective therapeutic effects. In the present study, the anticancer effects of drug‑loaded Fe3O4 magnetic nanoparticles (MNPs) by chemo‑photothermal th