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Publikováno v:
Molecular Medicine Reports
The C3a receptor (C3aR) has been reported to be involved in various physiological and pathological processes, including the regulation of cellular structure development. Expression of C3aR has been reported in podocytes; however, data concerning the
Publikováno v:
Oncology Reports
An aberrant elongated tract of glutamine residues (polyQ) in proteins induces multiple diseases treated in the clinic. In our previous study of progressive myoclonic epilepsy (PME), using whole‑exome sequencing, a mutant Cav2.1 protein with an aber
Publikováno v:
International Journal of Oncology
Cbl‑associated protein (CAP) is encoded by the sorbin and SH3 domain‑containing 1 (SORBS1) gene. CAP has been reported to be associated with the actin cytoskeleton, receptor tyrosine kinase signaling and cell adhesion through interactions with va
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate whether the cytoskeleton, the Piezo1 ion channel and the transient receptor potential cation channel subfamily V member 4 (TRPV4) ion channel are equally functional in the mechanotransduction of periodontal liga
Autor:
Raúl Solís‑Martínez, Luis Felipe Jave Suarez, Ana Laura Pereira‑Suárez, Annie Riera Leal, Adrián Ramírez De Arellano, Yveth Marlene Ortiz‑García, Carlos Alfredo Barrón‑Gallardo, Sonia Luquin De Anda, Pablo César Ortiz Lazareno, José Francisco Muñoz Valle, Adriana Aguilar Lemarroy
Publikováno v:
International Journal of Oncology
Mitochondria from different types of cancer show bioenergetics and dysfunction that favor cell proliferation. The mechanistic understanding of estrogen in cervical cancer is poorly understood. Therefore, the objective of this study was to determine h
Publikováno v:
Molecular Medicine Reports
Epithelial‑mesenchymal transition (EMT) provides a valuable source of fibroblasts that produce extracellular matrix in airway walls. The Sonic hedgehog (SHH) signaling pathway plays an essential role in regulating tissue turnover and homeostasis. S
Publikováno v:
Molecular Medicine Reports
Numerous studies have previously demonstrated that long non‑coding RNAs (lncRNAs) serve an important regulatory role in osteoarthritis (OA). In particular, the lncRNA family with sequence similarity 201 member A (FAM201A) was previously found to be
Publikováno v:
Molecular Medicine Reports
Astaxanthin (ASX), a red-colored xanthophyll carotenoid, functions as an antioxidant or pro-oxidant. ASX displays anticancer effects by reducing or increasing oxidative stress. Reactive oxygen species (ROS) promote cancer cell death by necroptosis me
Publikováno v:
Oncology Reports
Disturbed mitochondrial dynamics are closely associated with the progression of different types of cancer including hepatocellular carcinoma (HCC). However, the manner in which mitochondrial dynamics are regulated in HCC remains largely unclear. In t
Publikováno v:
Molecular Medicine Reports
Autophagy is a conserved catabolic process by which cytoplasmic components are delivered into lysosomes for degradation. Pigment epithelium‑derived factor (PEDF) has been reported to be associated with autophagy and can induce p53 expression; howev