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Publikováno v:
International Journal of Oncology
Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non‑Hodgkin lymphoma that is unique and different from systemic diffuse large B‑cell lymphomas. The median age at diagnosis of PCNSL is 65 years and its incidence is
Autor:
Kukiko Sakihama, Shinjiro Nagao, Akiko Fujimura, Kazunori Nakayama, Shu Ichimiya, Hideya Onishi, Yasuhiro Oyama, Satoko Koga, Akira Imaizumi, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Oncology Reports
We previously reported that Hedgehog (Hh) signal was enhanced in gallbladder cancer (GBC) and was involved in the induction of malignant phenotype of GBC. In recent years, therapeutics that target Hh signaling have focused on molecules downstream of
Publikováno v:
Oncology Reports
Emerging evidence has indicated that histone modification and its related regulators are involved in the progression of multiple myeloma (MM) cells. In the present study, the expression of Jumonji C domain‑containing 2 (JMJD2) was examined in both
Publikováno v:
Oncology Reports
Hsa_circ_0016760 expression has been reported to be increased in non‑small cell lung cancer (NSCLC). The present study was designed to explore the role and mechanism of hsa_circ_0016760 in regulating NSCLC progression. In total, 60NSCLC patients we
Publikováno v:
International Journal of Molecular Medicine
Deoxyribonucleic acid (DNA) epigenetic modification has been linked to specific sequences of CpG islands and plays roles in the progression of lung cancer. In this study, it was found that peroxiredoxin‑5 (PRDX5) was highly expressed in non‑small
Publikováno v:
International Journal of Molecular Medicine
Increasing evidence has demonstrated the important roles of long non‑coding (lnc) RNA in non‑small cell lung cancer (NSCLC). lncRNA gastric cancer‑associated transcript 1 (GACAT1) has been reported to play an oncogenic role in different types o
Publikováno v:
Oncology Reports
The aim of the present study was to investigate the effects of microRNA (miR)‑29b‑3p gene promoter methylation on angiogenesis, invasion, and migration in human pancreatic cancer. Prediction of promoter methylation of miR‑29b‑3p was performed
Publikováno v:
Oncology Reports
Currently, the prognosis of acute myeloid leukemia (AML) is poor. In the AML microenvironment, bone marrow (BM) mesenchymal stem cells (BMMSCs) serve an important role in protecting AML cells from chemotherapy‑induced apoptosis. The present study a
Publikováno v:
International Journal of Molecular Medicine
The inhibition of the proliferation and apoptosis of bone marrow-derived mesenchymal stem cells (BMSCs) triggered by the excessive use of glucocorticoids, is considered a potential mechanism for the pathogenesis of steroid-induced osteonecrosis of th
Autor:
Tiefu Xiong, Hongrui Zhan, Yawen Li, Zeng Zhang, Qiong Deng, Fangfang Chen, Liping Chen, Jing Ye
Publikováno v:
Oncology Reports
The long noncoding RNA cancer susceptibility candidate 9 (CASC9) has been revealed to be an oncogenic gene in several types of cancer, and high CASC9 expression is related to tumorigenesis and cancer progression. However, the role of CASC9 in bladder