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Autor:
Guolin Shi, Jin Wu, Jinyuan Yan, Qingchun Lei, Yingxia Guan, Tingting Wu, Xiaogang Hu, Ying Wang
Publikováno v:
Molecular Medicine Reports
Parkinson's disease (PD) is the second most common neurodegenerative disease amongst the middle‑aged and elderly populations. Several studies have confirmed that the microbiota‑gut‑brain axis (MGBA) serves a key role in the pathogenesis of PD.
Publikováno v:
Oncology Reports
Metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1) is a long non‑coding RNA that is overexpressed in various human cancers, including breast cancer. Evidence has associated the function of the α‑2,8‑sialyltransferase (ST8SIA) fa
Autor:
Jing Zhang, Furong Dai, Yanting Wu, Yao Xiao, Zhigang Sun, Qinggang Tian, Yun Liu, Jingling Yang, Tuankui Guo, Zhiqing Song, Wenfeng Gao, Yuguo Zhang
Publikováno v:
International Journal of Molecular Medicine
MicroRNAs (miRNAs or miRs) have been found to participate in the development and malignant progression of human cancers by negatively mediating the expression of their target genes. Recently, miR‑33b has been reported to be involved in multiple typ
Publikováno v:
Oncology Reports
MicroRNAs play an important role in tumor cell proliferation, invasion, and Rab23 is a member of the Ras‑related small GTPase family and plays a critical role in the progression of may types of tumors. The present study was designed to investigate
Autor:
Ya-Ling Hsu, Yung-Yun Chang, Chao-Yuan Chang, Kuan-Li Wu, Wei-An Chang, Yung-Chi Huang, Pei-Hsun Tsai, Ying-Ming Tsai, Shu-Fang Jian, Inn-Wen Chong, Jen-Yu Hung
Publikováno v:
Oncology Reports
Lung cancer remains notorious for its poor prognosis. Despite the advent of tyrosine kinase inhibitors and immune checkpoint inhibitors, the probability of curing the disease in lung cancer patients remains low. Novel mechanisms and treatment strateg
Publikováno v:
Molecular Medicine Reports
Girdin is an actin-binding Akt substrate that is involved in the regulation of cell migration. Accumulating evidence has revealed that girdin has regulatory effects on invasion and metastasis in several types of cancer. However, the role of girdin in
Publikováno v:
Oncology Reports
Gastric cancer (GC) is the third leading cause of cancer‑related mortality and the fifth most common type of cancer worldwide. GC stem cells (GCSCs) have been reported to be responsible for the malignant behavior of GC. However, the key molecular m
Publikováno v:
Molecular Medicine Reports
Long non‑coding RNAs (lncRNAs) are involved in the development and progression of a variety of diseases. However, the role of the lncRNA HLA complex group 11 (HCG11) in non‑small cell lung cancer (NSCLC) remains unclear. The present study showed
Autor:
Giovanna Grunewald Vietta, Alessandra Swarowsky Martin, Michele Patrícia Rode, Rudney da Silva, Tânia Beatriz Creczynski-Pasa, Rodrigo da Rosa Iop, Franciele Cascaes da Silva
Publikováno v:
Molecular Medicine Reports
There is a consensus regarding the efficacy of physical exercise in maintaining or improving human health; however, there are few studies examining the effect of physical exercise on the expression levels of microRNAs (miRNA/miRs) in Parkinson's dise
Autor:
You-Sheng Huang, Sisi Liu, Zhi-Fei Luo, Qiuping Meng, Feng-Gui Xue, Ying Li, Na Xie, Yixin Zhang
Publikováno v:
Molecular Medicine Reports
Aberrant expression of microRNAs (miRNAs/miRs) is associated with the initiation and progression of colorectal cancer (CRC), but how they regulate colorectal tumorigenesis is still unknown. The present study was designed to investigate the expression