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Publikováno v:
Molecular Medicine Reports
Growth arrest‑specific 5 (GAS5) is a known tumor suppressor which negatively regulates cell survival and malignancy in several cancer cell types. The present study aimed to establish the correlation between GAS5 and unc‑51 like autophagy activati
Autor:
Zhuo-Jun Yu, Yuan-Yan Tang, Zhi-Ping Huang, Yan Liang, Huimin Liu, Tao Xiong, Min Liu, Jiangzhao Zhang
Publikováno v:
Molecular Medicine Reports
Diffuse large B‑cell lymphoma (DLBCL) is the most common type of non‑Hodgkin lymphoma worldwide. Several studies have indicated that Homo sapiens (hsa)‑microRNA (miR)‑429 exerts a tumor‑suppressive effect on a variety of malignant tumors. T
Publikováno v:
Oncology Reports
Accumulating studies have suggested that microRNAs (miRs) play a significant role in lung cancer development and progression, especially in non‑small cell lung cancer (NSCLC). The present study aimed to investigate the associations between miR‑45
Publikováno v:
International Journal of Oncology
Long intergenic noncoding RNA 00961 (Linc00961) has been identified as a tumor suppressor in various types of cancer. However, the critical roles of Linc00961 in the carcinogenesis and progression of skin melanoma (SM) are yet to be fully elucidated.
Publikováno v:
Molecular Medicine Reports
Gastric cancer (GC) is a leading cause of cancer‑associated mortality worldwide. Previous studies demonstrated that long noncoding RNAs (lncRNAs) may be dysregulated in GC and may serve important roles in cancer progression. The present study aimed
Publikováno v:
Oncology Reports
As a core kinase in the Hippo pathway, large tumor suppressor kinase 2 (LATS2) regulates cell proliferation, migration and invasion through numerous signaling pathways. However, its functions on cell proliferation, migration and invasion in glioma ha
Autor:
Bingkun Zhao, Hui Xu, Hongming Song, Tianqi Wu, Changle Ji, Lin Fang, Kaiyao Hua, Jiashu Hu, Dan Xie, Dengfeng Li, Chenyang Wu, Yijun Deng
Publikováno v:
Oncology Reports
The aim of the present study was to define the function of microRNA-424-5p (miR-424) in breast cancer cells. The present study investigated the level and the potential function of miR-424 in breast cancer by reverse transcription-quantitative polymer
Autor:
Yun‑Min Lu, Yuan‑Fei Liu, Yuan Liu, Xiao‑Hong Liao, Wu‑Ming Kong, Guo‑Qiang Qu, Wei-Xiong Chen
Publikováno v:
Molecular Medicine Reports
Gastric cancer (GC) is the second most common cause of cancer-associated mortality worldwide. Previous studies suggest that mitogen-activated protein kinase kinase kinase kinase isoform 4 (MAP4K4) is involved in cancer cell growth, apoptosis and migr
Publikováno v:
International Journal of Molecular Medicine
Protocadherin-10 (PCDH10) which is located at 4q28.3, is a member of the cadherin superfamily of cell adhesion molecules. PCDH10 is broadly expressed in normal adult, but nearly undetectable in multiple myeloma (ΜΜ) tissues and cell lines. Its prom