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Publikováno v:
Molecular Medicine Reports
Girdin is an actin-binding Akt substrate that is involved in the regulation of cell migration. Accumulating evidence has revealed that girdin has regulatory effects on invasion and metastasis in several types of cancer. However, the role of girdin in
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the clinicopathological features of cases of classic Kaposi's sarcoma (CKS) in Xinjiang Uygur Autonomous Region, China, and analyze its etiology and treatment. A total of 114 patients, who were clinicopathologic
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the clinical significance of histone methylation in sepsis. A total of 43 blood samples from trauma and esophageal cancer patients with or without sepsis were collected. Immunofluorescence staining of isolated p
Publikováno v:
Molecular Medicine Reports
The present study aimed specifically investigate the expression and correlation of kelch-like ECH-associated protein‑1 (KEAP1), nuclear factor (erythroid-derived 2)‑like 2 (NRF2), quinone oxidoreductase‑1 (NQO‑1) and heme oxygenase‑1 (HO‑
Publikováno v:
Oncology Reports
Intraductal proliferative lesions of the breast including usual ductal hyperplasia (UDH), atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS) are associated with increased risk, albeit of greatly different magnitudes, for the subseq
Autor:
Hajime Morohashi, Yunyan Wu, Hiroshi Kijima, Shuji Terai, Tadashi Yoshizawa, Rie Ota, Satoko Morohashi, Toshihiro Haga, Kenichi Hakamada, Masafumi Takatsuna, Hideaki Hirai
Publikováno v:
Oncology Reports
Myofibroblasts of colorectal cancer (CRC) have been associated with histopathological factors such as lymph node metastasis, liver metastasis and local recurrence. However, few studies have assessed the association between these malignant potentials
Autor:
Takashi Ohtsu, Takeshi Kishida, Haruhiko Cho, Makoto Katayama, Akimune Hayashi, Yohei Miyagi, Manabu Shiozawa, Tsuyoshi Chijiwa, Roppei Yamada, Tomoyuki Yokose, Akira Noguchi, Masato Nakamura, Soichiro Morinaga, Kenji Kawai, Kohzoh Imai, Yasuo Takano, Hidemitsu Sato, Nobuo Takenaka, Hiroshi Suemizu, Yoshiyasu Nakamura
Publikováno v:
International Journal of Oncology
Viable and stable human cancer cell lines and animal models combined with adequate clinical information are essential for future advances in cancer research and patient care. Conventional in vitro cancer cell lines are commonly available; however, th
Publikováno v:
Molecular Medicine Reports
A disintegrin and metallopeptidase with thrombospondin motif type 1 (ADAMTS1) is a metalloproteinase with antiangiogenic activity. It was previously observed that the mRNA and protein levels of ADAMTS1 are downregulated in primary gastric tumors. The
Autor:
Fumihiro Higashino, Yoichi Ohiro, Masanobu Shindoh, Aya Yanagawa-Matsuda, Umma Habiba, Kyoko Hida, Tetsuya Kitamura, Yasunori Totsuka
Publikováno v:
Oncology Reports
Oral verrucous carcinoma (OVC) is a low grade variant of oral squamous cell carcinoma, and oral verrucous hyperplasia (OVH) is a benign lesion without malignant features. However, pathologists are sometimes presented with borderline lesions and are i
Autor:
Ikumi Imajyo, Naoya Yoshihama, Naonari Akimoto, Ieyoshi Kobayashi, Kotaro Ishii, Yosuke Kobayashi, Miyuki Shimoda, Yoshihide Mori, Tsuyoshi Sugiura
Publikováno v:
International Journal of Oncology
The prognosis of patients with oral squamous cell carcinoma (SCC) is influenced by the presence of lymph node metastasis. Epithelial-mesenchymal transition (EMT), a process that involves events that convert adherent epithelial cells into individual m