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Autor:
Kukiko Sakihama, Shinjiro Nagao, Akiko Fujimura, Kazunori Nakayama, Shu Ichimiya, Hideya Onishi, Yasuhiro Oyama, Satoko Koga, Akira Imaizumi, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Oncology Reports
We previously reported that Hedgehog (Hh) signal was enhanced in gallbladder cancer (GBC) and was involved in the induction of malignant phenotype of GBC. In recent years, therapeutics that target Hh signaling have focused on molecules downstream of
Publikováno v:
Oncology Reports
The aim of the present study was to investigate the effects of microRNA (miR)‑29b‑3p gene promoter methylation on angiogenesis, invasion, and migration in human pancreatic cancer. Prediction of promoter methylation of miR‑29b‑3p was performed
Publikováno v:
Oncology Reports
Currently, the prognosis of acute myeloid leukemia (AML) is poor. In the AML microenvironment, bone marrow (BM) mesenchymal stem cells (BMMSCs) serve an important role in protecting AML cells from chemotherapy‑induced apoptosis. The present study a
Autor:
Tiefu Xiong, Hongrui Zhan, Yawen Li, Zeng Zhang, Qiong Deng, Fangfang Chen, Liping Chen, Jing Ye
Publikováno v:
Oncology Reports
The long noncoding RNA cancer susceptibility candidate 9 (CASC9) has been revealed to be an oncogenic gene in several types of cancer, and high CASC9 expression is related to tumorigenesis and cancer progression. However, the role of CASC9 in bladder
Autor:
Shangzhi Xie, Xiao-Rui Luan, J. Zhang, Xiaoxiao Zheng, Hai-Ping Ke, Ke Chen, Rong-Rong Liu, Wei Chen, Xian-Ning Zhang, Yuexiao Tang
Publikováno v:
International Journal of Oncology
Hepatocellular carcinoma (HCC) is an invasive malignant neoplasm with a poor prognosis. The development of chemoresistance severely obstructs the chemotherapeutic efficiency of HCC treatment. Therefore, understanding the mechanisms of chemoresistance
Autor:
Min Zhang, Zhen Xiang, Feng Wang, Rong Shan, Ling Li, Juan Chen, Bao‑An Liu, Juan Huang, Lun‑Quan Sun, Wei‑Bing Zhou
Publikováno v:
Oncology Reports
Breast cancer (BRCA) is one of the most common malignancies encountered in women worldwide. Lipid metabolism has been found to be involved in cancer progression. Steroidogenic acute regulatory protein‑related lipid transfer 4 (STARD4) is an importa
Autor:
Minglei Li, Heng Song, Lingxiao Xing, Xianghong Zhang, Xiaosong Ding, Haitao Shen, Yuehong Li, Hui Li
Publikováno v:
International Journal of Oncology
Long non‑coding RNAs (lncRNAs) have emerged as key players in the development and progression of cancer. FEZ family zinc finger 1 antisense RNA 1 (FEZF1‑AS1) is a novel lncRNA that is involved in the development of cancer and acts as a potential
Publikováno v:
International Journal of Molecular Medicine
The long non-coding RNA KCNQ1OT1 is generally recognized as an oncogenic molecule in several human malignant tumors. However, to the best of our knowledge, the role of KCNQ1OT1 in glioma has not been fully investigated. The current study aimed to pro
Publikováno v:
International Journal of Oncology
Accumulating evidence suggests that inflammation is present in solid tumors. However, it is poorly understood whether inflammation exists in glioma and how it affects the metabolic signature of glioma. By analyzing immunohistochemical data and gene e
Publikováno v:
Oncology Reports
Long non‑coding RNA growth arrest specific 5 (GAS5) exerts inhibitory effects through the modulation of several target microRNAs (miRs) in cancer. However, its potential roles and underlying relationship during colorectal cancer (CRC) progression a