Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michael Snyder"'
Autor:
Shannon Rego, Michael Snyder
Publikováno v:
Cold Spring Harb Perspect Med
High-throughput sequencing has dramatically improved our ability to determine and diagnose the underlying causes of human disease. The use of whole-genome and whole-exome sequencing has facilitated faster and more cost-effective identification of new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd3e3f0d78e7fd316657f4dd5e754d4
https://europepmc.org/articles/PMC6314070/
https://europepmc.org/articles/PMC6314070/
Autor:
M. Reza Sailani, Safoura Mazrouei, Anil Narasimha, Jonathan A. Bernstein, Amin Zia, Janet Linnea Lynch, Omid Aryani, Michael Snyder, Inlora Jingga, James Chappell
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Progressive pseudorheumatoid dysplasia (PPD) is a skeletal dysplasia characterized by predominant involvement of articular cartilage with progressive joint stiffness. Here we report genetic characterization of a consanguineous family segregating an u
Autor:
Youngsook L. Jung, Marc D. Perry, Michael M. Hoffman, Joel Rozowsky, Florencia Pauli, Tao Liu, Matthew Slattery, Yiwen Chen, Qiang Li, Michael Snyder, Debasish Raha, Noam Shoresh, Anshul Kundaje, Katherine I. Fisher-Aylor, Gilberto DeSalvo, John A. Stamatoyannopoulos, Charles B. Epstein, Arend Sidow, Jason Gertz, Stephen G. Landt, Pouya Kheradpour, X. Shirley Liu, Manolis Kellis, Peggy J. Farnham, Ghia Euskirchen, Peter V. Kharchenko, Michael Y. Tolstorukov, Lijia Ma, Jason D. Lieb, Subhradip Karmakar, Aleksandar Milosavljevic, James B. Brown, Mark Gerstein, Philip Cayting, Timothy E. Reddy, Richard M. Myers, Peter J. Bickel, Alexander J. Hartemink, Michael J. Pazin, Peter J. Park, Barbara J. Wold, Kevin P. White, Georgi K. Marinov, Bradley E. Bernstein, Vishwanath R. Iyer, Simon Xi, Serafim Batzoglou
Publikováno v:
Genome Research
Chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-seq) has become a valuable and widely used approach for mapping the genomic location of transcription-factor binding and histone modifications in living cells. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5616e0d5640a45f356b2f95f7da55246
https://resolver.caltech.edu/CaltechAUTHORS:20120927-133114530
https://resolver.caltech.edu/CaltechAUTHORS:20120927-133114530
Autor:
Stephen Hartman, Milind Mahajan, Zheng Lian, Sherman M. Weissman, Jin Lian, Mark Gerstein, Alexander Karpikov, Michael Snyder
Genomic analyses have been applied extensively to analyze the process of transcription initiation in mammalian cells, but less to transcript 3′ end formation and transcription termination. We used a novel approach to prepare 3′ end fragments from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5485ea410be33ebce60cc8a8b32e03
https://europepmc.org/articles/PMC2493437/
https://europepmc.org/articles/PMC2493437/
Autor:
X. Shirley Liu, Philipp Kapranov, David Hawkins, D. Benjamin Gordon, Jayati Ghosh, Christoph M. Koch, Paul Flicek, Zhiping Weng, Alexander Karpikov, Jason D. Lieb, Nan Jiang, Richard M. Myers, Loan Nguyen, Xinmin Zhang, Xiaoqin Xu, David S. Johnson, Elizabeth Anton, David A. Nix, Peter C. Scacheri, Jason S. Carroll, Scott McCuine, Heather A. Hirsch, Zarmik Moqtaderi, Mark Gerstein, Zhen Ye, Yutao Fu, Wei Li, Keith A. Ching, Joel Rozowsky, Nathan D. Trinklein, Roland Green, Bo Curry, Hennady P. Shulha, Michael Snyder, Leonardo Brizuela, Kevin Struhl, Annie Yang, Sherman M. Weissman, Mark Bieda, Bing Ren, Arindam Bhattacharjee, H. Holster, Ghia Euskirchen, Jun S. Song, Peggy J. Farnham, Thomas R. Gingeras, Ian Dunham, Myles Brown
The most widely used method for detecting genome-wide protein–DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c495be6883baedda9b3bbb59dd6bfe41
https://europepmc.org/articles/PMC2259103/
https://europepmc.org/articles/PMC2259103/
Autor:
Michael Snyder, Zhengdong D. Zhang, Joseph T. Chang, Sherman M. Weissman, Alberto Paccanaro, Zhiping Weng, Mark Gerstein, Yutao Fu
The comprehensive inventory of functional elements in 44 human genomic regions carried out by the ENCODE Project Consortium enables for the first time a global analysis of the genomic distribution of transcriptional regulatory elements. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d2063e18d8d204f1e013d70f3f6eee
https://europepmc.org/articles/PMC1891338/
https://europepmc.org/articles/PMC1891338/
Autor:
Perry L. Miller, Roderic Guigó, Mark Gerstein, Jan O. Korbel, Jia Qian Wu, Michael Snyder, Joel Rozowsky, Sherman M. Weissman, Thomas R. Gingeras, Daniel E. Newburger, Jin Yang, Fred Sayward, Deyou Zheng, Ugrappa Nagalakshmi, Greg Jordan
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
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For the approximately 1% of the human genome in the ENCODE regions, only about half of the transcriptionally active regions (TARs) identified with tiling microarrays correspond to annotated exons. Here we categorize this large amount of "unannotated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05ca06d029cb48a3c77478df69fe48c
https://europepmc.org/articles/PMC1891334/
https://europepmc.org/articles/PMC1891334/
Autor:
Zhengdong D. Zhang, Michael Snyder, Wah Heng Lee, Sherman M. Weissman, Chia-Lin Wei, Olof Emanuelsson, Joel Rozowsky, Ghia Euskirchen, Stephen Hartman, Yijun Ruan, Viktor Stolc, Mark Gerstein
Recent progress in mapping transcription factor (TF) binding regions can largely be credited to chromatin immunoprecipitation (ChIP) technologies. We compared strategies for mapping TF binding regions in mammalian cells using two different ChIP schem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679384457daf954039c26aaaadf3b7c2
https://europepmc.org/articles/PMC1891348/
https://europepmc.org/articles/PMC1891348/
Autor:
Wei Chun Au, Li Ni, Ronald W. Davis, Munira A. Basrai, David C. Wheeler, Carole D. Carter, Hui Yang, Michael Snyder, Jef D. Boeke, Lauren E. Kitchen, Angela Chu, James P. Kastenmayer
Genes with small open reading frames (sORFs; Saccharomyces cerevisiae. Based on independent experimental approaches and computational analyses, evidence exists for 299 sORFs in the S. cerevisiae genome, representing ∼5% of the annotated ORFs. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659ddc3c9867fa74ac49423a97aca3f7
https://europepmc.org/articles/PMC1415214/
https://europepmc.org/articles/PMC1415214/
Autor:
Haiyuan Yu, Paul Bertone, Mark Gerstein, Michael Snyder, Anthony R. Borneman, Justine A. Leigh-Bell
To understand the organization of the transcriptional networks that govern cell differentiation, we have investigated the transcriptional circuitry controlling pseudohyphal development in Saccharomyces cerevisiae. The binding targets of Ste12, Tec1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb1f883d3b7a34aedd656ce738476c9
https://europepmc.org/articles/PMC1369046/
https://europepmc.org/articles/PMC1369046/