Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael Meyer-Hermann"'
A variety of B cell clones seed the germinal centers, where a selection stringency expands the fitter clones to generate higher affinity antibodies. However, recent experiments suggest that germinal centers often retain a diverse set of B cell clones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327b68331f978d656ba028c13db766b1
https://doi.org/10.1101/2022.10.26.513835
https://doi.org/10.1101/2022.10.26.513835
Autor:
Martin Kuhn, Margrit Klitz, Wadim Koslow, Daniel Abele, Michael Meyer-Hermann, Achim Basermann, Sebastian Binder
We analyze the relaxation of non-pharmaceutical interventions (NPIs) under an increasing number of vaccinations in Germany. For the spread of SARS-CoV-2 we employ a SIR-type model that accounts for age-dependence and includes realistic contact patter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3ae9ebe8c5de85ebfbee6b347fa48b
https://doi.org/10.1101/2021.07.09.21260257
https://doi.org/10.1101/2021.07.09.21260257
Follicular Dendritic Cells (FDCs) retain immune complexes (ICs) for prolonged time periods and are important for germinal center (GC) reactions. ICs undergo periodic cycling in FDCs, a mechanism supporting an extended half-life of antigen. Based on e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c64e11daee7baddd54a605d8a842ff2
https://doi.org/10.1101/2020.11.27.401315
https://doi.org/10.1101/2020.11.27.401315
Autor:
Jose Ordovas-Montanes, Ari Melnick, Jonatan Ersching, Michael Meyer-Hermann, Alex K. Shalek, Marta Schips, Tiago B. R. Castro, Alejo Efeyan, Luka Mesin, Gabriel D. Victora, Juhee Pae, Samuel J. Allon, Coraline Mlynarczyk
During affinity maturation, germinal center (GC) B cells alternate between proliferation and so-matic hypermutation in the dark zone (DZ) and affinity-dependent selection in the light zone (LZ). This anatomical segregation imposes that the vigorous p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2277048a9d1026d198daaa992c263513
https://doi.org/10.1101/2020.11.17.385716
https://doi.org/10.1101/2020.11.17.385716
Autor:
Sebastian Binder, Michael Meyer-Hermann, Tanmay Mitra, Marta Schips, Sahamoddin Khailaie, Arnab Bandyopadhyay
The novel Coronavirus SARS-CoV-2 (CoV) has induced a worldwide pandemic, notably in Italy, one of the worst-hit countries in Europe, which witnessed a death toll unseen in the recent past. There are potentially many factors, such as infections from u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c94d13a252d224c4f1f7b5e7cd1b84ab
https://doi.org/10.1101/2020.10.12.20211169
https://doi.org/10.1101/2020.10.12.20211169
Autor:
Marta Schips, Lydia Riepler, Barbara Falkensammer, Mrinalini Ranjan, Michael Meyer-Hermann, Ludwig Knabl, Hanno Ulmer, Janine Kimpel, Sebastian Binder, Arnab Bandyopadhyay, Tanmay Mitra, André Volland, Annika Rössler, Andreas Walser, Katie Bates, Lisa Pipperger, Dorothee von Laer, Wegene Borena
BackgroundEarly March 2020, a SARS-CoV-2 outbreak in the ski resort Ischgl in Austria initiated the spread of SARS-CoV-2 throughout Austria and Northern Europe.MethodsBetween April 21 and 27, a cross-sectional epidemiologic study targeting the full p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b1f13ae976b3c2f6184370bb5a55c5
Autor:
Sahamoddin Khailaie, Sebastian Binder, Timo Wollmershaeuser, Berit Lange, Florian Dorn, Stefan Lautenbacher, Andreas Peichl, Marc Stoeckli, Michael Meyer-Hermann, Clemens Fuest, Patrizio Vanella
Several countries use shutdown strategies to contain the spread of the COVID-19 epidemic, at the expense of massive economic costs. While this suggests a conflict between health protection and economic objectives, we examine whether the economically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb78ab83f122e6185164e6c1309efd9
https://doi.org/10.1101/2020.08.14.20175224
https://doi.org/10.1101/2020.08.14.20175224
Autor:
Masoud Hoore, Tanmay Mitra, Jeffrey Kelling, Marta Schips, Michael Meyer-Hermann, Mahsa Sayadmanesh
The Amyloid cascade hypothesis (ACH) for Alzheimer’s disease (AD) is modeled over the whole brain tissue with a set of partial differential equations. Our results show that the amyloid plaque formation is critically dependent on the secretion rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784aa8e4ab931433b14abc413b7bc4cd
https://doi.org/10.1101/2020.07.24.220228
https://doi.org/10.1101/2020.07.24.220228
Autor:
Pietro Mascheroni, Symeon Savvopoulos, Juan Carlos López Alfonso, Michael Meyer-Hermann, Haralampos Hatzikirou
In clinical practice, a plethora of medical examinations are conducted to assess the state of a patient’s pathology producing a variety of clinical data. However, exploiting these data faces the following challenges: (C1) we lack the knowledge of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9042074bd8ed775ecd51f6007a92c264
Autor:
Edward J. Carr, James Dooley, Michael Meyer-Hermann, Michelle A. Linterman, Danika L. Hill, Alice E Denton, Philippe Robert, Adrian Liston, Alyssa Silva-Cayetano
Publikováno v:
bioRxiv
Summary The failure to generate enduring humoral immunity after vaccination is a hallmark of advancing age. This can be attributed in part to a reduction in the germinal center response, which generates long-lived antibody-secreting cells that provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26af1f4914c92e6627bbbfb5521d5fd9
https://doi.org/10.1101/2020.05.07.082255
https://doi.org/10.1101/2020.05.07.082255