Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Liron Bar-Peled"'
Autor:
Tommy Weiss-Sadan, Maolin Ge, Addriaan de Groot, Alexander Carlin, Magdy Gohar, Hannah Fischer, Lei Shi, Ting-Yu Wei, Charles H. Adelmann, Tristan Vornbäumen, Benedkit R. Dürr, Mariko Takahashi, Marianne Richter, Junbing Zhang, Tzu-Yi Yang, Vindhya Vijay, Makiko Hayashi, David E. Fischer, Aaron N. Hata, Thales Papaginanakopoulos, Raul Mostoslavsky, Nabeel Bardeesy, Liron Bar-Peled
Multiple cancers regulate oxidative stress by activating the transcription factor NRF2 through mutation of its negative regulator KEAP1. NRF2 has been studied extensively in KEAP1-mutant cancers, however the role of this pathway in cancers with wildt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bca0f03c908f5891a12becbd18f540
https://doi.org/10.1101/2022.08.31.506025
https://doi.org/10.1101/2022.08.31.506025
Autor:
Benjamin F. Cravatt, Elizabeth R Valentine, Liron Bar-Peled, Michael Petrascheck, Mark A. McCormick, Alice L Chen, Megan M. Blewett, Rozina Kardakaris, Gregory M. Solis, Brian K. Kennedy, James R. Williamson
SummaryAging impairs the activation of Stress Signaling Pathways (SSPs), preventing the induction of longevity mechanisms late in life. Here we show that the antibiotic minocycline increases lifespan and reduces protein aggregation even in old, SSP-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5307af6399385c3c28f7c1f4d5605b