Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kenneth J. Livak"'
Autor:
Xuan Huang, Seungkyu Lee, Riki Kawaguchi, Ole Wiskow, Sulagna Ghosh, Devlin Frost, Laura Perrault, Roshan Pandey, Kuchuan Chen, Joseph R. Klim, Bruno Boivin, Crystal Hermawan, Kenneth J. Livak, Dan Geschwind, Brian J. Wainger, Kevin Eggan, Bruce P. Bean, Clifford J Woolf
The Kv8.1 potassium ion channel encoded by the KCNV1 gene is a “silent” subunit whose biological function is unknown. In ALS patient-derived motor neurons carrying SOD1(A4V) and C9orf72 mutations, its expression is highly reduced, yielding increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff65e2977922e80a2523734bae62801e
https://doi.org/10.1101/2023.05.07.539778
https://doi.org/10.1101/2023.05.07.539778
Autor:
Catherine J. Wu, Shuqiang Li, Dana Pe'er, Jerome Ritz, Pavan Bachireddy, Christina Ennis, Robert J. Soiffer, Zi-Ning Choo, Vinhkhang N Nguyen, Cassandra Burdziak, Elham Azizi, Kenneth J. Livak, Donna Neuberg, Edwin P. Alyea
Immune therapies have transformed the cancer therapeutic landscape but fail to benefit most patients. To elucidate the underlying mechanisms by which T cells mediate elimination of leukemia, we generated a high-resolution map of longitudinal T cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80a0ae51165fd3310473c96a8fa7e900
https://doi.org/10.1101/2020.07.08.194332
https://doi.org/10.1101/2020.07.08.194332
Autor:
Wei R Zhang, Amy Brock, Donna Neuberg, Kenneth J. Livak, Catherine Gutierrez, Sainan Li, Aziz Al'Khafaji, Catherine J. Wu, Kaitlyn E. Johnson, Russell E. Durrett, Eric Brenner
The remarkable evolutionary capacity of cancer is a major challenge to current therapeutic efforts. Fueling this evolution is its vast clonal heterogeneity and ability to adapt to diverse selective pressures. Although the genetic and transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071191e5e40adeac716b1e9b570d8900
https://doi.org/10.1101/761981
https://doi.org/10.1101/761981
Autor:
Kenneth J. Livak, Michael J. Ziller, Davide Cacchiarelli, Eliah G. Overbey, Sanjay Srivatsan, Cole Trapnell, Xiaojie Qiu, Prapti Pokharel, Alexander Meissner, Jonna Grimsby, Shuqiang Li, Tarjei S. Mikkelsen, John L. Rinn
Cellular reprogramming through manipulation of defined factors holds great promise for large-scale production of cell types needed for use in therapy, as well as for expanding our understanding of the general principles of gene regulation. MYOD-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfe3fb050bae6c761bf2e37e75dec1f
https://doi.org/10.1101/122531
https://doi.org/10.1101/122531
Publikováno v:
Genome Research. 11:436-440
When the temperature and viscosity of the solvent is held constant, the degree of fluorescence polarization (FP) detected when a fluorescent dye is excited by plane polarized light depends mostly on the molecular weight of the dye molecule. By monito
Publikováno v:
Genome Research. 8:549-556
Single-nucleotide variations are the most widely distributed genetic markers in the human genome. A subset of these variations, the substitution mutations, are responsible for most genetic disorders. As single nucleotide polymorphism (SNP) markers ar
Publikováno v:
Genome Research. 6:986-994
We have developed a novel "real time" quantitative PCR method. The method measures PCR product accumulation through a dual-labeled fluorogenic probe (i.e., TaqMan Probe). This method provides very accurate and reproducible quantitation of gene copies